Duquesne Family Office LLC — 13F Holdings & Portfolio

CIK 1536411 · latest 13F-HR filed 2026-05-15

Duquesne Family Office LLC manages $3.4M in 13F-reported U.S. long-equity assets across 70 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are NTRA (18.14%), INSM (5.59%), TSM (4.96%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 30 new positions, exited 23, added to 12, and trimmed 22.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$3.4M

Long-equity book

Holdings

70

Distinct positions

Period

2026-03-31

Filed 2026-05-15

Q/Q Activity

+30 / −23 / ↑12 / ↓22

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • Ypf Sociedad Anonima$127.6K +581.4%
  • Stmicroelectronics N V$70.2K +349.9%
  • Natera Inc$37.4K +6.5%
  • Alcoa Corp$25.9K +35.5%
  • Bbb Foods Inc$20.6K +23.1%
Show all 12

Top Trims

  • Amazon Com Inc-$160.8K -94.4%
  • Teva Pharmaceutical Inds Ltd-$111.8K -60.9%
  • Coupang Inc-$109.4K -68.5%
  • Woodward Inc-$103.0K -57.7%
  • Mercadolibre Inc-$90.2K -95.0%
Show all 22

New Positions

  • Broadcom Inc$60.6K
  • Global X Fds$36.2K
  • Caris Life Sciences Inc$33.9K
  • Revolution Medicines Inc$30.7K
  • Sandisk Corp$24.2K
Show all 30

Exited Positions

  • Select Sector Spdr Tr$301.0K
  • Invesco Exchange Traded Fd T$224.9K
  • Alphabet Inc$120.5K
  • Cogent Biosciences Inc$78.7K
  • Entegris Inc$71.1K
Show all 23
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 Natera Inc NTRA 632307104 $612.7K 18.14% 3,063,606 SH
2 Insmed Inc INSM 457669307 $188.7K 5.59% 1,154,090 SH
3 Taiwan Semiconductor Manufac TSM 874039100 $167.4K 4.96% 495,280 SH
4 Ishares Inc Call EWZ 464286400 $162.3K 4.81% 4,228,000 SH
5 Invesco Exchange Traded Fd T Call RSP 46137V357 $157.6K 4.67% 821,000 SH
6 Ypf Sociedad Anonima YPF 984245100 $149.6K 4.43% 3,235,962 SH
7 Ishares Inc EWZ 464286400 $131.9K 3.91% 3,436,170 SH
8 Bbb Foods Inc TBBB G0896C103 $110.0K 3.26% 3,109,202 SH
9 Alcoa Corp AA 013872106 $99.1K 2.93% 1,493,390 SH
10 Newamsterdam Pharma Company NAMS N62509109 $98.3K 2.91% 3,070,146 SH
11 Sea Ltd SE 81141R100 $91.1K 2.70% 1,099,905 SH
12 Stmicroelectronics N V STM 861012102 $90.3K 2.67% 2,612,880 SH
13 Woodward Inc WWD 980745103 $75.6K 2.24% 211,355 SH
14 Teva Pharmaceutical Inds Ltd TEVA 881624209 $71.6K 2.12% 2,377,285 SH
15 Roku Inc ROKU 77543R102 $71.0K 2.10% 750,190 SH
16 Broadcom Inc AVGO 11135F101 $60.6K 1.80% 195,955 SH
17 State Str Spdr S&P 500 Etf T Call SPY 78462F103 $58.5K 1.73% 90,000 SH
18 Coupang Inc CPNG 22266T109 $50.4K 1.49% 2,667,485 SH
19 Option Care Health Inc OPCH 68404L201 $50.3K 1.49% 1,868,550 SH
20 Amazon Com Inc Call AMZN 023135106 $41.7K 1.23% 200,000 SH
21 Crh Plc CRH G25508105 $39.7K 1.18% 377,555 SH
22 Figure Technology Solutio FIGR 349381103 $39.1K 1.16% 1,150,415 SH
23 Global X Fds ARGT 37950E259 $36.2K 1.07% 387,400 SH
24 Caris Life Sciences Inc CAI 142152107 $33.9K 1.00% 1,894,450 SH
25 Restaurant Brands Intl Inc QSR 76131D103 $33.6K 0.99% 454,435 SH
26 Revolution Medicines Inc RVMD 76155X100 $30.7K 0.91% 315,860 SH
27 Lattice Semiconductor Corp LSCC 518415104 $30.0K 0.89% 323,135 SH
28 Sandisk Corp SNDK 80004C200 $24.2K 0.72% 38,155 SH
29 United Airls Hldgs Inc UAL 910047109 $24.2K 0.72% 262,495 SH
30 Humana Inc HUM 444859102 $23.8K 0.71% 137,505 SH
31 Wabtec WAB 929740108 $23.7K 0.70% 94,895 SH
32 Twilio Inc TWLO 90138F102 $22.9K 0.68% 181,760 SH
33 Jabil Inc JBL 466313103 $21.8K 0.65% 82,200 SH
34 Southern Copper Corp SCCO 84265V105 $21.0K 0.62% 121,843 SH
35 Ishares S&P Gsci Commodity- GSG 46428R107 $20.7K 0.61% 643,000 SH
36 Linde Plc LIN G54950103 $20.4K 0.60% 41,200 SH
37 Seagate Technology Hldngs Pl STX G7997R103 $19.9K 0.59% 50,700 SH
38 Ishares Tr Call IWM 464287655 $19.6K 0.58% 79,000 SH
39 Cleveland-Cliffs Inc New CLF 185899101 $19.5K 0.58% 2,313,455 SH
40 Nuvation Bio Inc NUVB 67080N101 $19.5K 0.58% 4,539,800 SH
41 Bloom Energy Corp BE 093712107 $18.5K 0.55% 136,320 SH
42 Intel Corp INTC 458140100 $18.2K 0.54% 411,400 SH
43 Belite Bio Inc Sponsored BLTE 07782B104 $16.9K 0.50% 106,100 SH
44 Protagonist Therapeutics Inc PTGX 74366E102 $16.8K 0.50% 159,700 SH
45 Unity Software Inc U 91332U101 $16.2K 0.48% 738,785 SH
46 Arm Holdings Plc ARM 042068205 $16.1K 0.48% 106,700 SH
47 Olema Pharmaceuticals Inc OLMA 68062P106 $14.7K 0.44% 986,827 SH
48 Qnity Electronics Inc Q 74743L100 $14.5K 0.43% 125,655 SH
49 Adma Biologics Inc ADMA 000899104 $13.9K 0.41% 1,545,610 SH
50 Xenon Pharmaceuticals Inc XENE 98420N105 $13.9K 0.41% 238,600 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-15 $3.4M 70 0001536411-26-000004
2025-12-31 2026-02-17 $4.5M 62 0001536411-26-000002
2025-09-30 2025-11-14 $4.1M 65 0001536411-25-000017