TRV GP IV, LLC — 13F Holdings & Portfolio

CIK 1688325 · latest 13F-HR filed 2026-08-10

TRV GP IV, LLC manages $253.7M in 13F-reported U.S. long-equity assets across 2 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are MAZE (52.63%), TNGX (47.37%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 0 new positions, exited 0, added to 0, and trimmed 1.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

Filer Information
Address
201 BROOKLINE AVE, SUITE 1401
BOSTON, MA 02215
Phone
(617) 585-2000
Filing Manager
TRV GP IV, LLC
Boston, MA
Signatory
Kevin Gillis
Chief Operating Officer
Loading holdings…
AUM

$253.7M

Long-equity book

Holdings

2

Distinct positions

Period

2026-06-30

Filed 2026-08-10

Q/Q Activity

+0 / −0 / ↑0 / ↓1

vs 2026-03-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • No increased positions.
Show all 0

Top Trims

  • TANGO THERAPEUTICS, INC.-$13.2M -9.9%
Show all 1

New Positions

  • No new positions this quarter.
Show all 0

Exited Positions

  • No exits this quarter.
Show all 0
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 MAZE THERAPEUTICS, INC. MAZE 578784100 $133.5M 52.63% 4,473,958 SH
2 TANGO THERAPEUTICS, INC. TNGX 87583X109 $120.2M 47.37% 6,374,574 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-10 $253.7M 2 0001193125-26-340720
2026-03-31 2026-05-07 $266.9M 2 0001193125-26-212011
2025-12-31 2026-02-13 $255.1M 2 0001193125-26-051795