Alta Partners Management Company, L.P. — 13F Holdings & Portfolio

CIK 2054419 · latest 13F-HR filed 2026-04-21

Alta Partners Management Company, L.P. manages $151.0M in 13F-reported U.S. long-equity assets across 2 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are TYRA (96.97%), VIR (3.03%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 0 new positions, exited 0, added to 2, and trimmed 0.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$151.0M

Long-equity book

Holdings

2

Distinct positions

Period

2026-03-31

Filed 2026-04-21

Q/Q Activity

+0 / −0 / ↑2 / ↓0

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • TYRA BIOSCIENCES INC$45.9M +45.7%
  • VIR BIOTECHNOLOGY INC$1.5M +48.6%
Show all 2

Top Trims

  • No decreased positions.
Show all 0

New Positions

  • No new positions this quarter.
Show all 0

Exited Positions

  • No exits this quarter.
Show all 0
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 TYRA BIOSCIENCES INC TYRA 90240B106 $146.4M 96.97% 3,823,425 SH
2 VIR BIOTECHNOLOGY INC VIR 92764N102 $4.6M 3.03% 509,917 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-04-21 $151.0M 2 0002054419-26-000006
2025-12-31 2026-01-13 $103.6M 2 0002054419-26-000003