James C Hamilton

CIK 1830755 · Chief Medical Officer · last filed 2026-04-24

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

Loading insider history…
Disclosed Exposure

$19.48M

Companies

1

Total Filings

38

Lifetime Open-Market Net

-$14.39M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
ARWR Chief Medical Officer 226,958 $85.83 $19.48M -$14.39M 20 2026-04-24

Recent Filings · Page 2 of 4

38 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2025-10-01 ARWR Notice (144) −20,000 -$700.0K EDGAR
2025-09-16 ARWR Sell (S) −15,000 -$450.0K EDGAR
2025-09-12 ARWR Notice (144) −15,000 -$450.0K EDGAR
2025-09-04 ARWR Sell (S) −15,000 -$375.0K EDGAR
2025-09-02 ARWR Notice (144) −15,000 -$375.0K EDGAR
2025-08-15 ARWR Notice (144) −9,389 -$187.8K EDGAR
2025-08-15 ARWR Sell (S) −10,000 -$200.0K EDGAR
2025-08-13 ARWR Notice (144) −611 -$12.2K EDGAR
2025-01-07 ARWR Mixed +67,271 -$648.8K EDGAR
2025-01-06 ARWR Notice (144) −32,729 -$648.7K EDGAR
Showing 1120 of 38
Page 2 of 4
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.