ANVS · Insider Trading

Annovis Bio, Inc.

Every open-market purchase and sale reported by ANVS officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
9
code P
Sales
0
code S
Reporting Insiders
5
current holders
ANVS — Recent Form 4 Transactions (latest 2026-05-21)
FiledInsiderRole TypeSharesValue
2026-05-21 Michael B Hoffman Director Buy +76,344 +$142.78K
2026-04-03 Michael B Hoffman Director Buy +713,800 +$1.50M
2025-12-08 Michael B Hoffman Director Buy +45,000 +$193.79K
2025-11-25 Michael B Hoffman Director Buy +39,200 +$159.89K
2025-11-25 Michael B Hoffman Director Buy +39,200 +$159.89K
2025-11-21 Michael B Hoffman Director Buy +20,000 +$69.90K
2025-11-18 Michael B Hoffman Director Buy +15,000 +$31.65K
2025-11-12 Michael B Hoffman Director Buy +975,610 +$2.00M
2025-11-12 Maria-Luisa Maccecchini President & CEO Buy +97,561 +$200.00K
2025-11-12 Claudine Bruck Director M +7,142 +$1000
2025-09-03 Michael B Hoffman Director A +15,000 +$34.35K
2025-08-20 Michael B Hoffman Director A +18,645 +$48.28K
2025-06-18 Andrew Walsh Vice President, Finance A +500 +$1.45K
2025-06-16 Michael B Hoffman Director A +25,001 +$70.00K
2025-06-11 Reid McCarthy Director A +2,000 +$5.90K
2025-06-05 Maria-Luisa Maccecchini President & CEO A +46,000 +$155.02K
2025-06-02 Michael B Hoffman Director A +5,000 +$12.15K
2024-07-03 Michael B Hoffman Director A +29,600 deriv. —
2024-07-03 Reid McCarthy Director A +29,600 deriv. —
2024-07-03 Mark K. White Director A +48,346 deriv. —
2024-07-03 Maria-Luisa Maccecchini President and CEO G −30,000 —
2024-07-03 Claudine Bruck Director A +26,200 deriv. —
2023-11-22 Maria-Luisa Maccecchini President and CEO A +40,970 +$249.92K
2023-11-22 Mark K. White Director A +1,990 +$12.14K
2023-11-22 Henry Hagopian III Chief Financial Officer A +820 +$5.00K
2023-11-22 Reid McCarthy Director J — —
2023-11-22 Michael B Hoffman Director A +163,880 +$999.67K
2023-11-22 Claudine Bruck Director J — —
2023-11-21 Mark K. White Director A +2,000 +$12.14K
2023-11-21 Michael B Hoffman Director A +164,745 +$1.00M
2023-11-21 Maria-Luisa Maccecchini President and CEO A +41,186 +$250.00K
2023-11-21 Reid McCarthy Director A +824 +$5.00K
2023-11-21 Claudine Bruck Director A +1,000 +$6.07K
2023-11-21 Henry Hagopian III Chief Financial Officer A +824 +$5.00K
2023-04-26 Maria-Luisa Maccecchini President and CEO G −3,000 —
2023-04-11 Mark K. White Director A +3,000 +$37.83K
2023-04-11 Maria-Luisa Maccecchini President and CEO A +20,000 +$252.20K
2023-04-11 Henry Hagopian III Chief Financial Officer A +1,000 +$12.61K
2023-04-11 Michael B Hoffman Director A +59,477 +$750.00K
2023-04-11 Reid McCarthy Director A +476 +$6.00K
2023-04-11 Claudine Bruck Director A +500 +$6.30K
2023-02-08 Maria-Luisa Maccecchini President and CEO M +52,755 +$7.39K
2023-01-20 Claudine Bruck Director A +5,967 deriv. —
2023-01-20 Mark K. White Director A +5,967 deriv. —
2023-01-20 Michael B Hoffman Director A +6,820 deriv. —
2023-01-20 Maria-Luisa Maccecchini President and CEO A +21,312 deriv. —
2023-01-20 Henry Hagopian III Chief Financial Officer A +7,672 deriv. —
2023-01-20 Reid McCarthy Director A +5,967 deriv. —
2022-08-31 Henry Hagopian III Chief Financial Officer A +120,000 deriv. —
2022-01-18 Maria-Luisa Maccecchini President and CEO M +32,959 +$4.61K
ANVS — Current Insider Holders
InsiderRole Shares HeldValue
Michael B Hoffman Director 3,514,458 $3.36M
Maria-Luisa Maccecchini President & CEO 1,212,020 $1.16M
Claudine Bruck Director 13,709 $13.12K
Reid McCarthy Director 9,305 $8.90K
Andrew Walsh Vice President, Finance 500 $478
ANVS Insider Trading FAQ
Who are the insiders at ANVS?
5 officers, directors and 10%+ beneficial owners currently report holdings in ANVS via SEC Form 4.
Are ANVS insiders buying or selling?
Across the 50 most recent Form 4 filings for ANVS, 9 were open-market purchases (code P) and 0 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is ANVS insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent ANVS filing is dated 2026-05-21.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the ANVS quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.