KPTI · IV Rank History

Karyopharm Therapeutics Inc.

IV rank shows where KPTI's implied volatility sits within its own recent range: 0 is the lowest reading in the window, 100 the highest. This page gives the 52-week version, the 90-session version our screeners use, the IV percentile, and the daily history.

KPTI's 30-day at-the-money implied volatility was 522.4% as of Oct 23, 2026. Its 52-week IV rank is 86 and its IV percentile is 98%: IV was lower on 98% of the past year's sessions. Over those 52 weeks it ranged from 83.4% (Dec 12, 2025) to 596.0% (Oct 22, 2026). On the 90-session window our screeners use, the IV rank is 85.

KPTI IV rank history

504 sessions

Filled line: 90-session IV rank (0–100, left axis). Dashed line: 30-day at-the-money implied volatility (right axis).

KPTI IV rank and implied volatility as of 2026-10-23

52-Week IV Rank
86
0 = year low, 100 = year high
IV Percentile
98%
of past-year sessions had lower IV
90-Session IV Rank
85
used by our screeners
30-Day ATM IV
522.4%
1-year average 201.4%
52-Week IV High
596.0%
2026-10-22
52-Week IV Low
83.4%
2025-12-12
History Since
2023-05-04
538 sessions

How these are measured. Implied volatility here is KPTI's 30-day at-the-money IV: the implied volatility of the calls and puts struck nearest the share price, blended between the expirations on either side of 30 days so every reading covers the same horizon. It's the IV level options traders usually quote, and it doesn't jump when the nearest expiration rolls from a weekly to a monthly. The 7-day figure is the same measure a week out, so it reacts first to near-term events such as earnings.

52-week IV rank = (today's IV − 52-week low) ÷ (52-week high − 52-week low) × 100. IV percentile is the share of the past year's sessions that closed with lower IV than today. The 90-session IV rank applies the same rank formula to the last 90 sessions, so it reacts faster.

A high reading means KPTI options are expensive relative to their own recent history, which is common ahead of earnings or after a sharp move. It says nothing about which way the stock will go. The Vol Arb Screener ranks every tracked symbol by these measures.

KPTI implied volatility by month

MonthAvg ATM IVHighLowAvg IV Rank (90-session)
Oct 2026 (to date) 559.2% 596.0% 522.4% 92
Sep 2026 217.3% 244.9% 178.0% 51
Aug 2026 151.0% 203.0% 114.9% 18
Jul 2026 264.9% 330.2% 204.2% 38
Jun 2026 160.3% 202.7% 131.7% 14
May 2026 141.8% 166.6% 120.8% 11
Apr 2026 136.9% 216.6% 100.4% 12
Mar 2026 376.5% 535.0% 103.6% 72
Feb 2026 318.4% 411.5% 190.1% 81
Jan 2026 131.7% 215.8% 95.3% 19
Dec 2025 106.6% 132.9% 83.4% 8
Nov 2025 110.5% 133.4% 95.5% 8
Oct 2025 157.5% 339.2% 90.6% 28
Sep 2025 278.8% 314.0% 234.6% 80
Aug 2025 217.2% 272.3% 169.3% 50
Jul 2025 181.4% 315.1% 111.2% 20
Jun 2025 117.7% 142.9% 94.8% 5
May 2025 134.2% 243.2% 89.2% 7
Apr 2025 157.7% 348.8% 86.2% 10
Mar 2025 122.9% 140.7% 108.8% 6
Feb 2025 338.5% 772.8% 121.1% 37
Jan 2025 353.4% 536.3% 200.7% 65
Nov 2024 231.8% 274.1% 177.4% 37
Oct 2024 223.6% 355.3% 107.1% 35
Sep 2024 352.8% 486.2% 178.5% 68
Aug 2024 185.4% 459.3% 110.5% 29
Jul 2024 186.8% 411.6% 87.1% 32
Jun 2024 151.5% 218.0% 114.1% 19
May 2024 130.3% 210.9% 82.0% 13
Apr 2024 133.2% 159.0% 108.5% 13
Mar 2024 147.1% 193.8% 117.9% 17
Feb 2024 174.0% 448.1% 135.2% 24
Jun 2023 99.4% 111.8% 92.7% 27
May 2023 108.1% 135.4% 85.9% —

KPTI IV rank: last 30 sessions

DateIV Rank (90-session)30-Day ATM IV7-Day ATM IV
2026-10-23 85 522.4% —
2026-10-22 100 596.0% —
2026-09-30 60 244.2% —
2026-09-29 38 186.9% 145.5%
2026-09-28 57 231.1% 271.8%
2026-09-25 63 244.9% 274.5%
2026-09-24 45 202.7% —
2026-09-23 40 192.5% —
2026-09-22 61 239.7% —
2026-09-21 43 199.4% —
2026-09-18 53 222.4% —
2026-09-17 34 178.0% —
2026-09-15 52 219.1% 331.5%
2026-09-11 53 223.3% 194.9%
2026-09-10 57 231.5% 231.5%
2026-09-08 51 218.5% —
2026-09-04 59 235.8% 235.8%
2026-09-03 46 206.1% 206.1%
2026-08-31 33 177.3% 177.5%
2026-08-27 10 124.3% —
2026-08-24 6 114.9% —
2026-08-21 23 152.7% —
2026-08-13 16 138.0% —
2026-08-12 27 161.9% 204.7%
2026-08-11 26 203.0% 203.0%
2026-08-10 9 137.7% 168.9%
2026-08-05 12 148.9% 148.9%
2026-07-30 56 330.2% —
2026-07-29 52 326.4% —
2026-07-28 50 317.2% —

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.