TSHA · Insider Trading

Taysha Gene Therapies, Inc. Common Stock

Every open-market purchase and sale reported by TSHA officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
6
code P
Sales
9
code S
Reporting Insiders
8
current holders
TSHA — Recent Form 4 Transactions (latest 2026-07-10)
FiledInsiderRole TypeSharesValue
2026-07-10 Sukumar Nagendran President and Head of R&D Sell −200,000 −$1.25M
2026-06-02 Laura Sepp-Lorenzino Director A +21,335 —
2026-06-02 Alison S Long Director A +21,335 —
2026-06-02 John A Stalfort III Director A +21,335 —
2026-06-02 Phillip B. Donenberg Director A +21,335 —
2026-04-13 Sukumar Nagendran President and Head of R&D MIXED −180,979 −$859.47K
2026-02-06 Kamran Alam CHIEF FINANCIAL OFFICER Sell −1,655 −$7.48K
2026-01-27 Sukumar Nagendran President and Head of R&D Sell −116,050 −$547.47K
2026-01-27 Kamran Alam CHIEF FINANCIAL OFFICER Sell −102,817 −$485.04K
2026-01-27 Sean P. Nolan Chief Executive Officer Sell −178,101 −$840.20K
2026-01-14 Kamran Alam CHIEF FINANCIAL OFFICER A +359,000 —
2026-01-14 Sean P. Nolan Chief Executive Officer A +1,008,000 —
2026-01-14 Sukumar Nagendran President and Head of R&D MIXED +427,000 −$712.56K
2025-12-01 Sukumar Nagendran President and Head of R&D MIXED — −$1.13M
2025-09-12 Sukumar Nagendran President and Head of R&D MIXED −158,850 −$617.24K
2025-08-22 Sukumar Nagendran President and Head of R&D Sell −57,054 −$162.60K
2025-08-22 Kamran Alam CHIEF FINANCIAL OFFICER Sell −54,491 −$155.30K
2025-06-04 John A Stalfort III Director A +56,623 —
2025-06-04 Alison S Long Director A +56,623 —
2025-06-04 Phillip B. Donenberg Director A +56,623 —
2025-06-04 Laura Sepp-Lorenzino Director A +56,623 —
2025-06-03 Paul B Manning 10%+ Owner Buy +750,000 +$2.06M
2025-04-10 Kamran Alam CHIEF FINANCIAL OFFICER A +12,462 deriv. —
2025-03-13 Kamran Alam CHIEF FINANCIAL OFFICER F −29,843 −$50.43K
2025-01-03 Kamran Alam CHIEF FINANCIAL OFFICER A +431,000 —
2025-01-03 Sean P. Nolan Chief Executive Officer A +892,500 —
2025-01-03 Sukumar Nagendran President and Head of R&D A +324,500 —
2024-07-01 Paul B Manning 10%+ Owner Buy +1,333,333 +$3.00M
2024-05-31 Alison S Long Director A +49,220 —
2024-05-31 Laura Sepp-Lorenzino Director A +49,220 —
2024-05-31 Phillip B. Donenberg Director A +49,220 —
2024-05-31 John A Stalfort III Director A +49,220 —
2024-02-06 Kamran Alam CHIEF FINANCIAL OFFICER F −1,288 −$1.94K
2024-01-04 Kamran Alam Chief Financial Officer A +590,413 —
2024-01-04 Sean P. Nolan Chief Executive Officer A +1,184,688 —
2024-01-04 Sukumar Nagendran President and Head of R&D A +863,617 —
2023-12-18 Sean P. Nolan Chief Executive Officer A +466,550 deriv. —
2023-12-18 Kamran Alam Chief Financial Officer A +187,582 deriv. —
2023-12-18 Sukumar Nagendran President and Head of R&D A +334,005 deriv. —
2023-11-20 Paul B Manning 10%+ Owner Buy +100,000 +$163.00K
2023-11-03 Alison S Long Director A +43,800 deriv. —
2023-08-25 Kamran Alam Chief Financial Officer Sell −33,000 −$76.89K
2023-08-16 Phillip B. Donenberg Director Buy +111,111 +$100.00K
2023-08-16 Paul B Manning 10%+ Owner Buy +16,466,667 +$14.82M
2023-08-16 John A Stalfort III Director MIXED +827,778 +$700.00K
2023-08-16 Sean P. Nolan Chief Executive Officer Buy +444,444 +$400.00K
2023-07-14 R.A. Session II 10%+ Owner Sell −85,872 −$60.77K
2023-06-26 John A Stalfort III Director A +43,800 deriv. —
2023-06-26 Phillip B. Donenberg Director A +36,200 deriv. —
2023-06-26 Laura Sepp-Lorenzino Director A +36,200 deriv. —
TSHA — Current Insider Holders
InsiderRole Shares HeldValue
Sean P. Nolan Chief Executive Officer 4,443,802 $17.82M
John A Stalfort III Director 2,060,849 $8.26M
Kamran Alam CHIEF FINANCIAL OFFICER 1,442,131 $5.78M
Paul B Manning Director 1,355,333 $5.43M
Sukumar Nagendran President and Head of R&D 936,410 $3.76M
Phillip B. Donenberg Director 241,289 $967.57K
Laura Sepp-Lorenzino Director 127,178 $509.98K
Alison S Long Director 127,178 $509.98K
TSHA Insider Trading FAQ
Who are the insiders at TSHA?
8 officers, directors and 10%+ beneficial owners currently report holdings in TSHA via SEC Form 4.
Are TSHA insiders buying or selling?
Across the 50 most recent Form 4 filings for TSHA, 6 were open-market purchases (code P) and 9 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is TSHA insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent TSHA filing is dated 2026-07-10.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the TSHA quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.