International S.C.A. Artal

CIK 1218180 · last filed 2026-05-08

International S.C.A. Artal is a corporate insider who has filed 10 SEC Form 4 insider transactions across 4 companies since 2011. The most recent filing, for LXRX, was dated May 8, 2026. Across all open-market trades the lifetime net is −$563.8M, making them a net seller over the disclosed history. Current disclosed insider exposure totals $10.45B across reported positions. 75 SEC filings were submitted jointly with Artal Group S.A.

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure
$10.45B
Companies
4
Total Filings
10
Lifetime Open-Market Net
-$563.81M

Charts

Trading activity, where the exposure sits, and each trade against the stock price.

BUFF price and trades

Daily close with each Form 4 filing on this company marked: green = open-market buy, red = open-market sale, purple = grants, exercises, gifts and other non-market transactions. Marker size scales with the dollar value.

Shares held

Shares owned after each reported transaction on this company (direct holdings as reported).

Open-market buying and selling

by month

Dollar value of open-market purchases (code P, up) and sales (code S, down) across all companies, by filing month. Grants, exercises and gifts are excluded.

Exposure by company

latest
OfficerDirector10% owner* stale (no filing in 3 yrs)

Most recently reported shares × current price. Faded bars (*) have had no filing in 3 years, so the person may no longer hold them. Click a bar to chart that company.

Filer Profile

Reported Address
VALLEY PARK
44, RUE DE LA VALLEE
LUXEMBOURG, N4 L-2661
Phone
(352) 224-2591
Formerly Known As
ARTAL INTERNATIONAL SCA (2011–2012)
ARTAL INTERNATIONAL SA (2004–2004)
Related Filers
Artal Group S.A. — 75 joint filings, latest 2026-06-17
Westend S.A. — 75 joint filings, latest 2026-06-17
Administratiekantoor Westend Stichting — 73 joint filings, latest 2026-06-17
Artal International Management S.A. — 70 joint filings, latest 2026-06-17
Invus Public Equities Advisors, LLC — 40 joint filings, latest 2024-05-14
Invus Public Equities, L.P. — 40 joint filings, latest 2024-05-14
Pascal Minne — 38 joint filings, latest 2020-12-17
Amaury Wittouck — 31 joint filings, latest 2026-06-17
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
LXRX Director 175,156,062 $1.84 $322.29M $6.75M 2 2026-05-08
BUFF Director 99,972,999 $53.78 $5.38B -$319.58M 1 2016-07-07
Ceres, Inc. (CERE) Delisted 10%+ Owner — $44.96 — $0 1 2012-02-22
WTW 10%+ Owner 14,438,616 $329.14 $4.75B -$250.98M 1 2011-05-31

Recent Filings

10 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2026-05-08 LXRX Mixed +20,421,735 $0 EDGAR
2024-11-18 CAVA Notice (144) −8,000,000 -$1.13B EDGAR
2024-08-26 CAVA Notice (144) −6,000,000 -$732.00M EDGAR
2024-06-05 CAVA Notice (144) −3,000,000 -$265.02M EDGAR
2024-03-21 CAVA Notice (144) −2,000,000 -$136.64M EDGAR
2024-02-27 CAVA Notice (144) −3,500,000 -$176.75M EDGAR
2016-07-07 BUFF Sell (S) −15,014,548 -$319.58M EDGAR
2012-10-25 LXRX Buy (P) +3,000,000 $6.75M EDGAR
2012-02-22 Ceres, Inc. (CERE) Delisted Other (J) — $0 EDGAR
2011-05-31 WTW Sell (S) −3,000,000 -$250.98M EDGAR
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.