Laura Brege

CIK 1365619 · EVP, Corporate Affairs · last filed 2026-06-12

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$2.88M

Companies

11

Total Filings

110

Lifetime Open-Market Net

-$16.43M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
PCRX Director 30,120 $22.99 $692.5K -$1.24M 21 2026-06-12
ACAD Director 23,202 $21.09 $489.3K -$5.19M 31 2026-06-01
MIRM Director 15,703 $99.34 $1.56M -$1.15M 9 2025-09-12
EWTX Director $34.83 $0 4 2025-06-18
PORTOLA PHARMACEUTICALS INC (PTLA) Delisted Director 0 $0 7 2020-07-02
DYNAVAX TECHNOLOGIES CORP (DVAX) Delisted Director $15.50 $0 7 2019-05-31
ARATANA THERAPEUTICS, INC. (PETX) Delisted Director 13,500 $0 5 2018-07-30
DCTH Director 11,678 $11.72 $136.9K $0 3 2014-07-09
ONYX PHARMACEUTICALS INC (ONXX) Delisted EVP, Corporate Affairs 45,574 -$8.85M 20 2011-10-17
ANGIOTECH PHARMACEUTICALS INC (ANPI) Delisted Director $0 2 2009-12-14
ANGIOTECH PHARMACEUTICALS INC (JRT) Delisted Director $0 1 2008-12-10

Recent Filings · Page 11 of 11

110 filings
Form 4 transactions across all companies, newest first.
Filed Symbol Action Net Shares Net $ Link
2008-12-10 ANGIOTECH PHARMACEUTICALS INC (JRT) Delisted Grant (A) $0 EDGAR
2008-11-10 ONYX PHARMACEUTICALS INC (ONXX) Delisted Mixed -$182.0K EDGAR
2008-07-17 ONYX PHARMACEUTICALS INC (ONXX) Delisted Mixed -$275.8K EDGAR
2008-06-17 ACAD Grant (A) $0 EDGAR
2008-05-05 ACAD Exer (M) $0 EDGAR
2008-04-16 ONYX PHARMACEUTICALS INC (ONXX) Delisted Mixed -$222.2K EDGAR
2008-04-02 ONYX PHARMACEUTICALS INC (ONXX) Delisted Mixed +2,666 -$100.7K EDGAR
2008-01-16 ONYX PHARMACEUTICALS INC (ONXX) Delisted Mixed -$443.1K EDGAR
2007-08-14 ONYX PHARMACEUTICALS INC (ONXX) Delisted Mixed -$797.0K EDGAR
2007-04-02 ONYX PHARMACEUTICALS INC (ONXX) Delisted Grant (A) +10,000 $0 EDGAR
Showing 101110 of 110
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Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.