Laura Brege

CIK 1365619 · EVP, Corporate Affairs · last filed 2026-06-01

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$2.73M

Companies

11

Total Filings

109

Lifetime Open-Market Net

-$16.43M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
ACAD Director 23,202 $21.09 $489.3K -$5.19M 31 2026-06-01
MIRM Director 15,703 $99.34 $1.56M -$1.15M 9 2025-09-12
EWTX Director $34.83 $0 4 2025-06-18
PCRX Director 23,715 $22.99 $545.2K -$1.24M 20 2025-06-13
PORTOLA PHARMACEUTICALS INC (PTLA) Delisted Director 0 $0 7 2020-07-02
DYNAVAX TECHNOLOGIES CORP (DVAX) Delisted Director $15.50 $0 7 2019-05-31
ARATANA THERAPEUTICS, INC. (PETX) Delisted Director 13,500 $0 5 2018-07-30
DCTH Director 11,678 $11.72 $136.9K $0 3 2014-07-09
ONYX PHARMACEUTICALS INC (ONXX) Delisted EVP, Corporate Affairs 45,574 -$8.85M 20 2011-10-17
ANGIOTECH PHARMACEUTICALS INC (ANPI) Delisted Director $0 2 2009-12-14
ANGIOTECH PHARMACEUTICALS INC (JRT) Delisted Director $0 1 2008-12-10

Recent Filings · Page 3 of 11

109 filings
Form 4 transactions across all companies, newest first.
Filed Symbol Action Net Shares Net $ Link
2022-06-28 EWTX Grant (A) $0 EDGAR
2022-06-09 ACAD Grant (A) $0 EDGAR
2022-06-08 PCRX Grant (A) +1,160 $0 EDGAR
2022-06-06 MIRM Grant (A) $0 EDGAR
2021-06-24 ACAD Grant (A) $0 EDGAR
2021-06-11 PCRX Grant (A) +1,066 $0 EDGAR
2021-06-08 MIRM Grant (A) $0 EDGAR
2020-11-17 PCRX Mixed -$623.6K EDGAR
2020-07-02 PORTOLA PHARMACEUTICALS INC (PTLA) Delisted Disp (D) −20,475 -$368.6K EDGAR
2020-06-25 ACAD Grant (A) $0 EDGAR
Showing 2130 of 109
Page 3 of 11
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.