Aprea Therapeutics, Inc. Common stock(APRE)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
Fair Value
+50.0% vs price
Confidence: 13% Alpha Score: 14.97

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.53%
Beta vs SPY1.00
Cost of Equity (CAPM)9.53%
WACC9.51%
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+3.0%
DCF Horizon10 years explicit + fade
Forward Tilt (NTM/TTM)×1.03 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$-0.0B
Return on Equity (TTM)-28.7%
Book / Price645.6% — banking bias active (P/B is primary)
Gross Margin (TTM)100.0%
FCF Margin (TTM)-9748.9%
Debt / Equity0.00
Quality Score2/6 — normal (10y DCF)
SMA 50$0.85 (Market Anchor value)
SMA 20 / Bollinger Mid$0.84
Bollinger Width / SMA204498.7% (drives anchor stability)
Net Debt$-0.0B
Market Cap$0B
Peers used for multiples: ABT, PFE, REGN, TEVA (SIC-code peers; ETF co-membership was sector-incoherent)
Blended Fair Value
$6.18
Current Price
$0.69
Deviation
+50.0%
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0% median 22.1× · 4 peers
Peer EV/EBITDA n/a 0% median 12.8× · 4 peers
Peer P/B $12.32 50% median 2.5× · 4 peers
Peer P/S $0.04 50% median 2.9× · 4 peers
Market Anchor (SMA50) $0.85 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-06-12 · updated 2026-06-12 20:59:55.687000
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.0B

Aprea Therapeutics Inc is a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers. It develops small molecule inhibitors designed to exploit genetic mutations in cancer to widen the therapeutic window and is intended to make treatments more effective at destroying cancer cells while sparing healthy tissue. The company's pipeline of clinical and preclinical programs includes APR-1051, a WEE1 inhibitor; ATRN-119 (Mosipasertib), an oral small molecule inhibitor of ataxia telangiectasia and Rad3…

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan +2.91% 7
Feb -3.26% 7
Mar -11.37% 7
Apr -10.67% 7
May -8.82% 7
Jun -0.85% 7
Jul -4.96% 6
Aug -0.77% 6
Sep -5.04% 6
Oct +9.20% 7
Nov -10.27% 7
Dec -5.76% 7
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $0.83
SMA 50: $0.85
SMA 200: $1.03
Current: $0.69
EMA 12: $0.77
EMA 26: $0.81
MACD: -0.0395 | Signal: -0.0153
BEARISH
ADX (14): 20.18
WEAK TREND
+DI: 13.73
−DI: 27.61
Momentum Oscillators
RSI (14): 35.26
NEUTRAL
Stoch %K: 19.42
Stoch %D: 18.38
Williams %R: -88.72
Volume & Volatility
BB Upper: $0.99
BB Lower: $0.66
NEUTRAL
OBV: 116,422,993
Vol SMA 20: 142,550
Vol ROC: 209.60%
ATR: $0.08
True Range: $0.11
HV 20: 84.6%
HV 30: 84.8%
HV 60: 96.7%

Data Summary
Data Points: 500
Last Updated: 2026-06-12T21:15:07.928000
Date Range: 2024-06-14T00:00:00 – 2026-06-12T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
0
IV Rank (7D)
0
Avg IV
0.0%
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
1.29
Correlation (SPY)
17.8%
0.03
Ann. Volatility
89.3%
SPY Volatility
12.3%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 8,420,109 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

21 filers2,299,010 shares$1.77M value27.30% of float
# Filer Shares Value % of Total % of Float Period
1 AIGH Capital Management LLC 1,015,541 $774.76K 43.87% 12.06% 2026-03-31
2 Vestal Point Capital, LP 350,000 $267.01K 15.12% 4.16% 2026-03-31
3 SPHERA FUNDS MANAGEMENT LTD. 270,000 $205.98K 11.66% 3.21% 2026-03-31
4 Nantahala Capital Management, LLC 205,760 $156.97K 8.89% 2.44% 2026-03-31
5 GEODE CAPITAL MANAGEMENT, LLC Custodian 119,131 $90.89K 5.15% 1.41% 2026-03-31
6 MORGAN STANLEY Custodian 77,030 $65.71K 3.72% 0.91% 2025-12-31
7 VANGUARD GROUP INC Custodian 58,086 $49.55K 2.81% 0.69% 2025-12-31
8 Scientech Research LLC 60,281 $45.99K 2.60% 0.72% 2026-03-31
9 BNP PARIBAS FINANCIAL MARKETS Custodian 39,817 $30.38K 1.72% 0.47% 2026-03-31
10 RENAISSANCE TECHNOLOGIES LLC 25,100 $19.15K 1.08% 0.30% 2026-03-31
11 LPL Financial LLC Custodian 21,052 $16.06K 0.91% 0.25% 2026-03-31
12 HighTower Advisors, LLC 13,864 $10.58K 0.60% 0.16% 2026-03-31
13 TWO SIGMA SECURITIES, LLC 13,500 $10.30K 0.58% 0.16% 2026-03-31
14 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian 13,018 $9.93K 0.56% 0.15% 2026-03-31
15 BlackRock, Inc. Custodian 8,504 $6.49K 0.37% 0.10% 2026-03-31
16 Tower Research Capital LLC (TRC) Custodian 5,127 $3.91K 0.22% 0.06% 2026-03-31
17 UBS Group AG Custodian 2,153 $1.64K 0.09% 0.03% 2026-03-31
18 GROUP ONE TRADING LLC Custodian 577 $440 0.02% <0.01% 2026-03-31
19 OSAIC HOLDINGS, INC. Custodian 295 $225 0.01% <0.01% 2026-03-31
20 WealthCollab, LLC 158 $121 <0.01% <0.01% 2026-03-31
21 SBI Securities Co., Ltd. 16 $12 <0.01% <0.01% 2026-03-31
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Insider Activity
Latest: 2026-04-01
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-04-01 Richard Peters Director Buy (P) +247,830 RSU EDGAR
2026-04-01 John P. Hamill SrVP/CFO/Prin Fin & Acct Ofcr Buy (P) +61,956 RSU EDGAR
2026-03-16 John P. Hamill SrVP/CFO/Prin Fin & Acct Ofcr Award (A) +10,095 EDGAR
2026-03-16 Oren Gilad President/CEO Award (A) +20,175 EDGAR
2026-02-02 John P. Hamill SrVP/CFO/Prin Fin & Acct Ofcr Buy (P) +5,700 $0.89 $5.1K EDGAR
2026-02-02 Oren Gilad President/CEO Buy (P) +28,100 $0.89 $25.0K EDGAR
2025-12-11 John P. Hamill SrVP/CFO/Prin Fin & Acct Ofcr Buy (P) +5,000 $1.17 $5.8K EDGAR
2025-12-11 Oren Gilad President/CEO Buy (P) EDGAR
2025-12-11 Marc Duey Director Buy (P) +21,459 $1.17 $25.0K EDGAR
2025-06-09 Michael Grissinger Director Award (A) +1,045 EDGAR
2025-06-09 Bernd R. Seizinger Director Award (A) +1,045 EDGAR
2025-06-09 Gabriela Gruia Director Award (A) +1,045 EDGAR
2025-06-09 JEAN-PIERRE BIZZARI Director Award (A) +1,045 EDGAR
2025-06-09 Marc Duey Director Award (A) +1,045 EDGAR
2025-06-09 JOHN B III HENNEMAN Director Award (A) +1,045 EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
33 insiders · @ $0.69
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Johan Christenson Director 2,366,104 $1.62M $4.00M 2 2020-07-01
2 Investments AB KDev 10%+ Owner 1,992,586 $1.37M -$44.79M 3 2020-07-07
3 5AM Opportunities I (GP), LLC 10%+ Owner 1,938,549 $1.33M -$56.36M 1 2020-06-15
4 KUSH PARMAR 10%+ Owner 1,926,073 $1.32M $40.00M 1 2019-10-09
5 Redmile Group, LLC 10%+ Owner 1,868,718 $1.28M $12.00M 1 2019-10-08
6 Jeremy Green 10%+ Owner 1,768,718 $1.21M -$5.58M 1 2021-02-16
7 HealthCap VII, L.P. 10%+ Owner 1,671,941 $1.15M $8.00M 1 2019-10-07
8 Oren Gilad President/CEO 395,095 $271.1K $55.4K 12 2026-03-16
9 5AM Ventures IV, L.P. 10%+ Owner 333,333 $228.7K -$71.71M 1 2020-05-21
10 CHRISTIAN S SCHADE Chairman & CEO 264,246 $181.3K $114.1K 8 2022-08-01
11 Marc Duey Director 256,757 $176.2K $127.6K 8 2025-12-11
12 Versant Vantage I, L.P. 10%+ Owner 216,669 $148.7K $0 1 2020-05-20
13 Scott M Coiante SVP, Chief Financial Officer 145,065 $99.5K $37.5K 8 2022-08-01
14 5AM Co-Investors IV, L.P. 10%+ Owner 75,965 $52.1K -$37.30M 1 2020-06-18
15 JOHN D DIEKMAN 75,965 $52.1K -$39.85M 1 2020-10-07
16 SCOTT M ROCKLAGE Director 75,965 $52.1K -$20.01M 5 2020-07-01
17 Eyal C. Attar SVP, Chief Medical Officer 57,392 $39.4K -$131.0K 8 2022-06-07
18 Bernd R. Seizinger Director 45,775 $31.4K $149.3K 11 2025-06-09
19 Gregory Alan Korbel SVP, Chief Operating Officer 45,762 $31.4K -$537.2K 14 2022-08-01
20 Lars B. Abrahmsen SVP, Chief Scientific Officer 43,700 $30.0K -$368.8K 6 2022-03-14
21 John P. Hamill SrVP/CFO/Prin Fin & Acct Ofcr 43,528 $29.9K $19.6K 11 2026-04-01
22 Rifat Pamukcu Director 19,554 $13.4K $0 4 2025-06-09
23 Gregory S. Wessels SVP, Chief Commercial Officer 16,000 $11.0K $0 2 2021-03-01
24 JOHN B III HENNEMAN Director 10,229 $7.0K $125.0K 8 2025-06-09
25 Nadeem Q. Mirza Chief Medical Officer 6,730 $4.6K $0 1 2024-05-02
26 Guido Magni Director 6,500 $4.5K $97.5K 1 2019-10-07
27 Michael Aaron Kelly Director 4,610 $3.2K $0 2 2021-07-01
28 Fouad Namouni Director 4,610 $3.2K $0 2 2021-07-01
29 Richard Peters Director 3,119 $2.1K $0 7 2026-04-01
30 Michael Grissinger Director 2,889 $2.0K $0 4 2025-06-09
31 Versant Affiliates Fund V, L.P. 10%+ Owner 1,178 $808 $0 1 2020-05-20
32 JEAN-PIERRE BIZZARI Director 1,045 $717 $0 2 2025-06-09
33 Gabriela Gruia Director 1,045 $717 $0 2 2025-06-09
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/B Ratio0.2
P/S Ratio77.3
EV/EBITDA2.9
TTM Revenue$0.0B
TTM Net Income$-0.0B
TTM EPS$-1.5
ROE-28.7%