ETON · Insider Trading

Eton Pharmaceutcials, Inc. Common Stock

Every open-market purchase and sale reported by ETON officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
3
code P
Sales
8
code S
Reporting Insiders
9
current holders
ETON — Recent Form 4 Transactions (latest 2026-10-06)
FiledInsiderRole TypeSharesValue
2026-10-06 David Krempa Chief Business Officer MIXED +6,356 −$229.41K
2026-08-31 Paul V Maier Director MIXED +12,500 −$2.67M
2026-08-28 Paul V Maier Director MIXED — −$2.76M
2026-08-24 David Krempa Chief Business Officer MIXED — −$1.44M
2026-08-20 Sean Brynjelsen President & CEO Sell −100,000 −$6.09M
2026-08-04 David Krempa Chief Business Officer A +128,985 deriv. —
2026-08-04 Ipek Erdogan-Trinkaus Chief Commercial Officer A +80,000 deriv. —
2026-08-04 Jennifer McKie Adams Director A +10,000 deriv. —
2026-08-04 Judith M. Matthews Chief Financial Officer A +32,246 deriv. —
2026-08-04 Sean Brynjelsen President & CEO A +128,985 deriv. —
2026-08-04 Charles J Casamento Director A +10,000 deriv. —
2026-08-04 Norbert G Riedel Director A +10,000 deriv. —
2026-08-04 Paul V Maier Director A +10,000 deriv. —
2026-07-17 Opaleye Management Inc. 10%+ Owner Sell −28,315 −$1.06M
2026-07-16 Opaleye Management Inc. 10%+ Owner Sell −28,315 −$1.06M
2026-07-14 Sean Brynjelsen President & CEO M +227,500 +$274.00K
2026-07-13 David Krempa Chief Business Officer M +10,000 —
2026-07-07 Opaleye Management Inc. 10%+ Owner Sell −126,685 −$4.77M
2026-06-17 Jennifer McKie Adams Director MIXED — −$1.43M
2026-05-29 Sean Brynjelsen President & CEO Sell −120,000 −$3.83M
2026-05-27 David Krempa Chief Business Officer MIXED −12,206 −$3.03M
2026-04-22 Norbert G Riedel Director M +32,155 +$260.60K
2026-02-05 Norbert G Riedel Director X +30,000 +$132.60K
2026-01-14 Paul V Maier Director A +19,953 deriv. —
2026-01-14 Ipek Erdogan-Trinkaus Chief Commercial Officer A +66,511 deriv. —
2026-01-14 Jennifer McKie Adams Director A +19,953 deriv. —
2026-01-14 Sean Brynjelsen President & CEO F −5,015 −$77.18K
2026-01-14 David Krempa Chief Business Officer F −1,942 −$30.33K
2026-01-14 Norbert G Riedel Director A +19,953 deriv. —
2026-01-14 James R. Gruber Chief Financial Officer F −2,293 −$35.47K
2026-01-14 Charles J Casamento Director A +19,953 deriv. —
2025-12-12 Ipek Erdogan-Trinkaus Chief Commercial Officer F −85 −$1.44K
2025-12-12 Sean Brynjelsen President & CEO F −6,732 −$113.30K
2025-12-12 David Krempa Chief Business Officer F −6,264 −$106.49K
2025-12-12 James R. Gruber Chief Financial Officer F −4,542 −$77.17K
2025-08-20 James R. Gruber Chief Financial Officer Sell −41,713 −$673.71K
2025-06-16 David Krempa Chief Business Officer Sell −34,000 −$504.32K
2025-06-12 Opaleye Management Inc. 10%+ Owner Buy +7,930 +$125.48K
2025-06-05 Sean Brynjelsen President & CEO Sell −210,000 −$3.59M
2025-01-06 Jennifer McKie Adams Director A +25,000 deriv. —
2025-01-06 James R. Gruber Chief Financial Officer A +64,497 deriv. —
2025-01-06 David Krempa Chief Business Officer A +64,497 deriv. —
2025-01-06 Sean Brynjelsen President & CEO A +179,473 deriv. —
2025-01-06 Norbert G Riedel Director A +25,000 deriv. —
2025-01-06 Norbert G Riedel Director M +102,400 +$373.84K
2025-01-06 Charles J Casamento Director A +25,000 deriv. —
2025-01-06 Paul V Maier Director A +25,000 deriv. —
2024-10-25 Opaleye Management Inc. 10%+ Owner Buy +10,000 +$79.81K
2024-10-08 Opaleye Management Inc. 10%+ Owner Buy +62,070 +$434.14K
2024-10-04 David Krempa Chief Business Officer A +42,088 deriv. —
ETON — Current Insider Holders
InsiderRole Shares HeldValue
Opaleye Management Inc. 10%+ Owner 2,665,000 $133.70M
Sean Brynjelsen President & CEO 1,077,156 $54.04M
Norbert G Riedel Director 224,300 $11.25M
James R. Gruber Chief Financial Officer 213,420 $10.71M
Charles J Casamento Director 71,920 $3.61M
Paul V Maier Director 59,745 $3.00M
Jennifer McKie Adams Director 50,000 $2.51M
David Krempa Chief Business Officer 47,547 $2.39M
Ipek Erdogan-Trinkaus Chief Commercial Officer 2,403 $120.56K
ETON Insider Trading FAQ
Who are the insiders at ETON?
9 officers, directors and 10%+ beneficial owners currently report holdings in ETON via SEC Form 4.
Are ETON insiders buying or selling?
Across the 50 most recent Form 4 filings for ETON, 3 were open-market purchases (code P) and 8 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is ETON insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent ETON filing is dated 2026-10-06.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the ETON quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.