MGX Metagenomi Therapeutics, Inc. Common Stock
XNAS
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
- Industry (SIC)
- BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836) · industry map
- Exchange
- XNAS
- Market Cap
- $0.0B
- Employees
- 113
- List Date
- 2024-02-09
- CIK
- 0001785279
- Next Earnings
- 2026-11-10
- EPS Forecast
- ($0.74) (2 est.)
- Headquarters
- Emeryville, CA
- Homepage
- https://metagenomi.co
Metagenomi Therapeutics Inc is an vivo genome editing company capitalizing on its proprietary technologies to create curative genetic medicines for patients. The company leverages machine learning and artificial intelligence to enhance its signature gene editing systems. MGX-001 is its, wholly-owned development program in hemophilia A, where the company have demonstrated targeted genome editing and durable gene expression from a one-time treatment in non-human primates (NHPs) and an overall profile potentially competitive with best-in-class treatment options. MGX-001 is designed to provide cur…
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
| Month | '24 | '25 | '26 | Avg |
|---|---|---|---|---|
| Jan | -- | -29.02% | -7.78% | -18.40% |
| Feb | 15.03% | -18.33% | -1.30% | -1.53% |
| Mar | -12.08% | -26.88% | -12.42% | -17.13% |
| Apr | -35.12% | 31.06% | 2.99% | -0.36% |
| May | -9.38% | 14.09% | -2.16% | 0.85% |
| Jun | -39.01% | -15.91% | -9.16% | -21.36% |
| Jul | -12.22% | 51.82% | -2.06% | 12.51% |
| Aug | -15.14% | -22.67% | -2.48% | -13.43% |
| Sep | -24.91% | 30.22% | -9.40% | -1.36% |
| Oct | -4.83% | 6.28% | -30.55%* | -9.70% |
| Nov | -1.90% | -27.69% | -- | -14.79% |
| Dec | 73.56% | 1.25% | -- | 37.41% |
| Total | -67.13% | -36.60% | -56.15% | -53.29% |
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
Momentum Oscillators
Volume & Volatility
Data Summary
LLM Stock Analysis Report: MGX
Executive Summary:
Overall Assessment: NEUTRAL (confidence level: 6/10)
Key Drivers and Primary Risks:
- Recent news headlines highlighting positive developments in Metagenomi Therapeutics' pipeline and technology advancements.
- Technical indicators suggesting a potential range-bound trading environment, with some bearish momentum signals.
Investment Thesis: MGX may continue to experience volatility as it navigates the development of its compact CRISPR nuclease technology and clinical trial progress. While news sentiment is generally positive, technical signals suggest a neutral-to-bearish bias.
Recent News Sentiment Impact: The recent news headlines have contributed to a generally positive sentiment, with all six articles highlighting positive developments in Metagenomi Therapeutics' pipeline and technology advancements.
Technical Analysis:
Trend Direction: Short-term (1-4 weeks): NEUTRAL Medium-term (1-3 months): RANGE-BOUND Long-term (3-12 months): UPTRENDING
Support/Resistance Levels: Key price levels:
- Lower Bollinger Band: $1.15
- Middle Line: $1.20
- Upper Bollinger Band: $1.25
- SMA 50: $1.22
- SMA 200: $1.43
Momentum Signals:
- RSI (14): 38.05 (neutral)
- MACD: -0.02 / Signal: -0.00 / Histogram: -0.01 (bearish)
Volume Analysis: Volume trends:
- Volume SMA 20: 152158.25
- On-Balance Volume (OBV): 85793719.28
- Volume Rate of Change: 39.06%
News & Sentiment Analysis:
Recent Headlines Summary: Positive news headlines highlight Metagenomi Therapeutics' pipeline and technology advancements.
Sentiment Assessment: Aggregate sentiment is POSITIVE, with all six recent articles contributing to this assessment.
Catalyst Identification: Upcoming scientific meetings and presentation of data highlighting advancements in next-generation genome editing technologies.
Market Narrative: News sentiment aligns with the technical signals, suggesting a neutral-to-bearish bias in the short term.
Risk & Volatility Assessment:
Risk Metrics: Beta: 1.57 (vs SPY) Alpha: -0.55 Correlation: 0.32
Stock Volatility: 0.63 Interpretation: High volatility - stock moves more than market
Options Market Signals: No options data available.
Downside Protection: Support levels:
- Lower Bollinger Band: $1.15
- Middle Line: $1.20
- SMA 50: $1.22
Market Context & Positioning:
Sector Performance: Metagenomi Therapeutics is part of the Biotechnology sector, which has experienced moderate growth.
Institutional Activity: Volume patterns suggest institutional interest in MGX's stock.
Correlation Analysis: MGX moves relatively independently of the market (R-squared interpretation).
Relative Valuation: MGX is trading within its historical range, with no clear valuation signal.
Key Levels & Action Items:
Critical Price Levels: Support/resistance levels:
- Lower Bollinger Band: $1.15
- Middle Line: $1.20
- Upper Bollinger Band: $1.25
- SMA 50: $1.22
- SMA 200: $1.43
Breakout/Breakdown Levels: No clear breakout or breakdown levels.
Time-Sensitive Catalysts: Upcoming scientific meetings and presentation of data highlighting advancements in next-generation genome editing technologies.
Risk Management: Stop-loss levels:
- Lower Bollinger Band: $1.15
- Middle Line: $1.20
Position sizing considerations:
- Consider hedging strategies if the stock moves significantly away from support/resistance levels.
By analyzing MGX's technical indicators, news sentiment, and risk metrics, it appears that the stock may continue to experience volatility as it navigates the development of its compact CRISPR nuclease technology and clinical trial progress. While news sentiment is generally positive, technical signals suggest a neutral-to-bearish bias in the short term.
| Earnings Date | Timing | Expected Move | Actual Move | Ratio | Outcome |
|---|---|---|---|---|---|
| 2026-08-11 | unknown | — | 0.83% | — | Within |
Earnings calendar: this week’s reports with expected vs actual moves →
MGX Options Activity & IV Rank
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Enter a ticker to render the implied volatility surface.
Enter a ticker to render the implied volatility smile.
Risk Metrics
Analysis Details
Data Points: 251
Period: 252 trading days
High volatility - stock moves more than market
| Investor | Value | Share of their portfolio | Rank | Q/Q shares | Source |
|---|---|---|---|---|---|
| Renaissance Technologies Hedge fund Jim Simons | $883K | #2370 of 3138 | -5.8% | 13F | |
| Millennium Management Hedge fund Izzy Englander | $136K | #3567 of 3716 | -33.0% | 13F | |
| Citadel Hedge fund Ken Griffin | $21K | #6166 of 6285 | +5.0% | 13F |
Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions
MGX Institutional Ownership (13F)
Latest filings — 2026-09-30Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|
| # | Filer | Notional Value | % of Total | Period |
|---|
MGX Insider Trading (Form 4)
Latest: 2026-09-11| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2026-09-11 | Laurence Reid | Director | Buy (P) | +20,000 | $1.17 | $23.4K | EDGAR |
| 2026-09-10 | Pamela Wapnick | Chief Financial Officer | Sell (S) | −1,911 | $1.16 | -$2.2K | EDGAR |
| 2026-09-10 | Matthew Wein | See Remarks | Sell (S) | −358 | $1.16 | -$415 | EDGAR |
| 2026-09-10 | Jian Irish | See Remarks | Sell (S) | −2,140 | $1.16 | -$2.5K | EDGAR |
| 2026-06-11 | Eric Bjerkholt | Director | Grant (A) | +21,000 opt | — | EDGAR | |
| 2026-06-11 | Laurence Reid | Director | Grant (A) | +17,400 opt | — | EDGAR | |
| 2026-06-11 | Willard H Dere | Director | Grant (A) | +21,000 opt | — | EDGAR | |
| 2026-06-11 | Juergen Eckhardt | Director | Grant (A) | +21,000 opt | — | EDGAR | |
| 2026-06-10 | Matthew Wein | See Remarks | Sell (S) | −558 | $1.30 | -$725 | EDGAR |
| 2026-06-10 | Pamela Wapnick | Chief Financial Officer | Sell (S) | −2,884 | $1.30 | -$3.7K | EDGAR |
| 2026-06-10 | Jian Irish | See Remarks | Sell (S) | −3,737 | $1.30 | -$4.9K | EDGAR |
| 2026-04-03 | Jian Irish | See Remarks | Award (A) | +46,000 | — | EDGAR | |
| 2026-04-03 | Matthew Wein | See Remarks | Award (A) | +11,000 | — | EDGAR | |
| 2026-04-03 | Pamela Wapnick | Chief Financial Officer | Award (A) | +24,000 | — | EDGAR | |
| 2026-03-09 | Pamela Wapnick | Chief Financial Officer | Sell (S) | −1,581 | $1.60 | -$2.5K | EDGAR |
MGX Insider Holdings
6 insiders · @ $0.77| # | Insider | Role | Shares | Disclosed Exposure | Lifetime OM Net | Filings | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Brian C. Thomas | Chief Executive Officer | 2,510,960 | $1.93M | -$30.5K | 5 | 2025-12-08 |
| 2 | Jian Irish | See Remarks | 668,107 | $512.7K | -$26.8K | 9 | 2026-09-10 |
| 3 | Pamela Wapnick | Chief Financial Officer | 206,580 | $158.5K | -$41.2K | 12 | 2026-09-10 |
| 4 | Matthew Wein | See Remarks | 126,133 | $96.8K | -$4.7K | 10 | 2026-09-10 |
| 5 | Sarah B. Noonberg | Chief Medical Officer | 109,135 | $83.8K | -$9.2K | 3 | 2025-06-09 |
| 6 | Laurence Reid | Director | 20,000 | $15.3K | $23.4K | 3 | 2026-09-11 |
MGX Board & Officers
As of SEC filings through Sep 11, 2026Directors 5
- Jian Irish · since Feb 8, 2024
- Juergen Eckhardt · since Feb 8, 2024
- Willard H Dere · since Feb 8, 2024
- Eric Bjerkholt · since Jan 27, 2025
- Laurence Reid · since Aug 11, 2025
Officers 4
- Jian Irish · President and Chief Executive Officer · listed since Jun 2026
- Pamela Wapnick · Chief Financial Officer · since Feb 8, 2024
- Sarah B. Noonberg · Chief Medical Officer · since Feb 8, 2024
- Matthew Wein · Title: General Counsel, Compliance Officer and Corporate Secretary · listed since Dec 2025
Changes in the last 10 years (26)
| Jun 10, 2026 | Jian Irish listed as President and Chief Executive Officer (previously Chief Executive Officer) in SEC filings |
| Jun 9, 2026 | The company announced the departure of Brian C. Thomas from the board in an SEC filing |
| Dec 1, 2025 | Matthew Wein listed as Title: General Counsel, Compliance Officer and Corporate Secretary (previously Title: Vice President of Corporate Legal and Compliance, and Corporate Secretary) in SEC filings |
| Dec 1, 2025 | Jian Irish listed as Chief Executive Officer (previously Title: President and Chief Operating Officer) in SEC filings |
| Dec 1, 2025 | Brian C. Thomas no longer listed as Chief Executive Officer in SEC filings |
| Aug 11, 2025 | Laurence Reid became a director |
| Jan 27, 2025 | Eric Bjerkholt became a director |
| Feb 15, 2024 | Novo Holdings A/S reported in an SEC filing no longer being a 10% owner |
| Feb 8, 2024 | Willard H Dere became a director |
| Feb 8, 2024 | Simren Delaney became Title: Vice President of Intellectual Property and Legal Operations |
| Feb 8, 2024 | Simon Harnest became Title: Chief Investment Officer and Senior Vice President of Strategy |
| Feb 8, 2024 | Sebastian Bernales became a director |
| Feb 8, 2024 | Sarah B. Noonberg became Chief Medical Officer |
| Feb 8, 2024 | Pamela Wapnick became Chief Financial Officer |
| Feb 8, 2024 | Novo Holdings A/S became a 10% owner |
| Feb 8, 2024 | Matthew Wein became Title: Vice President of Corporate Legal and Compliance, and Corporate Secretary |
| Feb 8, 2024 | Luis Borges became Chief Scientific Officer |
| Feb 8, 2024 | Juergen Eckhardt became a director |
| Feb 8, 2024 | Jian Irish became a director |
| Feb 8, 2024 | Jian Irish became Title: President and Chief Operating Officer |
| Feb 8, 2024 | Brian C. Thomas became a director |
| Feb 8, 2024 | Brian C. Thomas became Chief Executive Officer |
| Feb 8, 2024 | Bayer World Investments B.V. became a 10% owner |
| Feb 8, 2024 | Bayer US Holding LP became a 10% owner |
| Feb 8, 2024 | Bayer Healthcare LLC became a 10% owner |
| Feb 8, 2024 | Aktiengesellschaft Bayer became a 10% owner |
- Prev
- 1
Not reported recently (8)
- Simon Harnest · Last reported as Title: Chief Investment Officer and Senior Vice President of Strategy in an SEC filing dated Apr 3, 2024
- Sebastian Bernales · Last reported as a director in an SEC filing dated Apr 3, 2024
- Luis Borges · Last reported as Chief Scientific Officer in an SEC filing dated Apr 3, 2024
- Simren Delaney · Last reported as Title: Vice President of Intellectual Property and Legal Operations in an SEC filing dated Apr 3, 2024
- Bayer World Investments B.V. · Last reported as a 10% owner in an SEC filing dated Feb 15, 2024
- Bayer Healthcare LLC · Last reported as a 10% owner in an SEC filing dated Feb 15, 2024
- Bayer US Holding LP · Last reported as a 10% owner in an SEC filing dated Feb 15, 2024
- Aktiengesellschaft Bayer · Last reported as a 10% owner in an SEC filing dated Feb 15, 2024
MGX Proposed Insider Sales (Form 144)
Latest: 2025-09-11What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.
How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.
10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.
"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.
Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.
| Filed | Filer | Role | Shares | Notice Value | Planned Sale | Broker | Plan | Link |
|---|---|---|---|---|---|---|---|---|
| 2025-09-11 | Noonberg Sarah B. | FORMER OFFICER | 35,832 | $68.1K | 2025-09-11 | MERRILL LYNCH | — | EDGAR |
| 2025-07-09 | Sebastian Bernales | Affiliate | 769,845 | $1.47M | 2025-07-09 | J.P. Morgan Securities LLC | — | EDGAR |
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|---|---|---|---|---|---|
| 1 | VTI Vanguard Morningstar Total Stock Market ETF | Vanguard | 0.00% | $785,891 | — | 2026-09-30 |
| 2 | ISCF iShares International Small-Cap Equity Factor ETF | iShares (BlackRock) | 0.06% | $402,644 | $699.5M | 2026-10-23 |
| 3 | VXF Vanguard Extended Market ETF | Vanguard | 0.00% | $334,388 | — | 2026-09-30 |
| 4 | IWC iShares Micro-Cap ETF | iShares (BlackRock) | 0.01% | $70,341 | $1.2B | 2026-10-23 |
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.