SNTI Senti Biosciences Holdings, Inc. Common Stock

XNAS
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SNTI — —
Key stats
About
Industry (SIC)
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836) · industry map
Exchange
XNAS
Market Cap
$0.0B
Employees
39
List Date
2022-06-09
CIK
0001854270
Next Earnings
2026-11-12
EPS Forecast
($0.38) (1 est.)
Headquarters
South San Francisco, CA
Homepage
https://www.sentibio.com

Senti Biosciences Holdings Inc, formerly known as Senti Biosciences Inc, is a clinical-stage biotechnology company developing cell and gene therapies using its gene circuit platform for patients with incurable diseases. Its gene circuits, created from proprietary DNA sequences, are designed to reprogram cells to sense, compute, and respond to cellular environments. Its product candidates are to kill cancer cells, spare healthy cells, increase specificity, and control drug expression. Its candidate, SENTI-202, is a logic-gated off-the-shelf CAR-NK cell therapy for blood cancers, currently in a …

Summary
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composite
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No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
Month'22'23'24'25'26Avg
Jan--23.83%-31.91%14.44%-9.09%-0.68%
Feb---17.13%-6.05%-31.44%-6.54%-15.29%
Mar---17.48%-12.51%17.48%-12.77%-6.32%
Apr---14.04%-3.51%2.34%10.25%-1.24%
May---9.90%-21.05%-3.38%-6.71%-10.26%
Jun-68.91%-28.61%-7.88%-31.72%12.21%-24.98%
Jul63.87%33.60%-44.67%-22.37%-68.47%-7.61%
Aug-30.99%-30.46%22.69%-12.50%2.22%-9.81%
Sep7.96%-38.70%-14.07%-1.40%-8.18%-10.88%
Oct-7.20%-34.92%-3.98%40.97%-46.02%*-10.23%
Nov-6.50%48.82%-0.92%11.50%--13.22%
Dec-38.70%50.00%-64.90%-49.51%---25.78%
Total-79.81%-61.26%-92.35%-66.92%-86.34%-77.34%
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $0.27
SMA 50: $0.32
SMA 200: $0.74
Current: $0.18
EMA 12: $0.23
EMA 26: $0.27
MACD: -0.0399 | Signal: -0.0087
BEARISH
ADX (14): 32.05
TREND
+DI: 8.41
−DI: 30.18

Momentum Oscillators

RSI (14): 23.50
OVERSOLD
Stoch %K: 5.21
Stoch %D: 6.00
Williams %R: -97.22

Volume & Volatility

BB Upper: $0.38
BB Lower: $0.16
NEUTRAL
OBV: 13,869,909
Vol SMA 20: 3,185,255
Vol ROC: 25672.73%
ATR: $0.03
True Range: $0.02
HV 20: 117.4%
HV 30: 103.8%
HV 60: 94.9%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-10-28T00:00:00 – 2026-10-26T00:00:00
AI Analysis

Click Frenzy-Pro™ for an AI analysis of this ticker.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

SNTI Options Activity & IV Rank

Loading options activity...
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
ATM — / Wing —
30 DTE / 10d —
— pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis

Risk Metrics

Beta: 2.1823
Alpha: -219.71%
Correlation: 0.2750
R-Squared: 7.6%
Stock Volatility: 101.1%
Market Volatility: 12.7%

Analysis Details

Benchmark: SPY
Data Points: 251
Period: 252 trading days
Interpretation:
High volatility - stock moves more than market
Beta & Alpha Over Time
Notable investors who own SNTI
1 of 37 tracked investors
InvestorValueShare of their portfolioRankQ/Q sharesSource
Citadel Hedge fund
Ken Griffin
$118K
0.00%
#5718 of 6285new13F

Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions

SNTI Institutional Ownership (13F)

Latest filings — 2026-09-30

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

21 filers5,571,003 shares$6.09M value
# Filer Shares Value % of Total % of Float Period
1 NEA Management Company, LLC 3,775,615 $4.15M 68.23% — 2026-06-30
2 Vanguard Group Inc Custodian 628,697 $653.85K 10.74% — 2025-12-31
3 Vanguard Capital Management LLC 537,504 $591.25K 9.71% — 2026-06-30
4 Geode Capital Management, LLC Custodian 187,065 $205.78K 3.38% — 2026-06-30
5 Citadel Advisors LLC Custodian 107,100 $117.81K 1.94% — 2026-06-30
6 Vanguard Fiduciary Trust Co 91,193 $100.31K 1.65% — 2026-06-30
7 Jane Street Group, LLC Custodian 52,530 $57.78K 0.95% — 2026-06-30
8 Menlo Ventures Management, L.P. 35,737 $39.31K 0.65% — 2026-06-30
9 MSOP GP, L.L.C. 35,737 $37.17K 0.61% — 2025-12-31
10 Northern Trust Corp Custodian 32,154 $35.37K 0.58% — 2026-06-30
11 XTX Topco Ltd 23,610 $25.97K 0.43% — 2026-06-30
12 Virtu Financial LLC 22,795 $25.00K 0.41% — 2026-06-30
13 UBS Group AG Custodian 14,432 $15.88K 0.26% — 2026-06-30
14 State Street Corp 10,010 $11.01K 0.18% — 2026-06-30
15 Tower Research Capital LLC (TRC) Custodian 7,344 $8.08K 0.13% — 2026-06-30
16 BlackRock, Inc. Custodian 4,004 $4.40K 0.07% — 2026-06-30
17 Royal Bank of Canada Custodian 4,015 $4.00K 0.07% — 2026-06-30
18 Barclays PLC Custodian 768 $845 0.01% — 2026-06-30
19 Morgan Stanley Custodian 169 $186 <0.01% — 2026-06-30
20 SBI Securities Co., Ltd. 523 $163 <0.01% — 2026-09-30
21 Caitong International Asset Management Co., Ltd 1 $1 0.00% — 2026-06-30
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period

SNTI Insider Trading (Form 4)

Latest: 2026-10-23
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-10-23 Timothy K Lu CEO Tax (F) −157,312 — EDGAR
2026-10-23 Kanya Rajangam Pres. & Chief Med. & Dev. Off. Tax (F) −19,953 — EDGAR
2026-03-11 Timothy K Lu CEO Tax (F) −80,666 — EDGAR
2026-03-11 Kanya Rajangam Pres. & Chief Med. & Dev. Off. Tax (F) −10,757 — EDGAR
2026-02-03 Timothy K Lu CEO Tax (F) −4,191 — EDGAR
2026-02-03 Kanya Rajangam Pres. & Chief Med. & Dev. Off. Tax (F) −1,384 — EDGAR
2025-07-21 Bryan Daniel Baum Director Grant (A) +43,900 opt — EDGAR
2025-06-27 Donald F Tang Director Grant (A) +21,950 opt — EDGAR
2025-06-27 James J. Collins Director Grant (A) +21,950 opt — EDGAR
2025-06-27 Brenda Cooperstone Director Grant (A) +21,950 opt — EDGAR
2025-06-27 Edward T Mathers Director Grant (A) +21,950 opt — EDGAR
2025-06-27 Fran Schulz Director Grant (A) +21,950 opt — EDGAR
2025-06-27 Feng Hsiung Director Grant (A) +21,950 opt — EDGAR
2025-03-14 Celadon Partners SPV 24 10%+ Owner Conv (C) +9,777,000 — EDGAR
2025-03-12 Bayer World Investments B.V. 10%+ Owner Conv (C) +8,888,000 — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.

SNTI Insider Holdings

6 insiders · @ $0.18
Officers, directors, and 10%+ owners who have filed a Form 4 in the past two years, ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Celadon Partners SPV 24 10%+ Owner 9,777,000 $1.71M $0 1 2025-03-14
2 Scott D Sandell 10%+ Owner 3,775,615 $661.1K $0 1 2025-03-12
3 Bayer World Investments B.V. 10%+ Owner 2,809,848 $492.0K $0 1 2025-03-12
4 Aktiengesellschaft Bayer 10%+ Owner 587,848 $102.9K $0 1 2024-12-11
5 Timothy K Lu CEO 535,110 $93.7K -$18.3K 7 2026-10-23
6 Kanya Rajangam Pres. & Chief Med. & Dev. Off. 87,890 $15.4K -$6.1K 10 2026-10-23
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.

SNTI Board & Officers

As of SEC filings through Oct 23, 2026

Directors 6

Officers 1

Changes in the last 10 years (48)
Oct 23, 2026Kanya Rajangam reported in an SEC filing no longer being Pres. & Chief Med. & Dev. Off.
Sep 23, 2026The company announced the departure of Brenda Cooperstone from the board in an SEC filing
Feb 3, 2026Timothy K Lu listed as CEO (previously CEO and President) in SEC filings
Jul 18, 2025Bryan Daniel Baum became a director
Mar 7, 2025Feng Hsiung became a director
Mar 6, 2025Celadon Partners SPV 24 became a 10% owner
Mar 3, 2025John Harry Cross III became Chief Financial Officer
Dec 10, 2024Kanya Rajangam listed as Pres. & Chief Med. & Dev. Off. (previously Chief Medical & Devt. Officer) in SEC filings
Dec 9, 2024Fran Schulz became a director
Dec 9, 2024Donald F Tang became a director
Dec 2, 2024The company announced the departure of Omid Farokhzad from the board in an SEC filing
May 4, 2024Yvonne Li became Interim CFO
Apr 23, 2024The company announced the departure of Deborah Knobelman as Chief Financial Officer in an SEC filing
Aug 7, 2023The company announced the departure of Philip J Lee as Chief Technology Officer in an SEC filing
Jul 26, 2022The company announced the departure of Curt A. Herberts III as Chief Operating Officer in an SEC filing
Jul 13, 2022The company announced the departure of Timothy K Lu from the board in an SEC filing
Jul 5, 2022Kanya Rajangam became Chief Medical & Devt. Officer
Jun 10, 2022Dynamics Sponsor LLC reported in an SEC filing no longer being a 10% owner
Jun 8, 2022Timothy K Lu became a director
Jun 8, 2022Timothy K Lu became CEO and President
Not reported recently (22)
Compiled from SEC filings by the company and its directors and officers. Dates are as stated in those filings. Where no filing says when someone left, we show the last filing that listed them.

SNTI Proposed Insider Sales (Form 144)

Latest: 2024-12-02
Last 30d: 0 filings  ·  Last 90d: 0 filings

What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.

How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.

10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.

"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.

Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.

Filed Filer Role Shares Notice Value Planned Sale Broker Plan Link
2024-12-02 Omid C Farokhzad Former Affiliate 83,277 $179.9K 2024-12-02 J.P. Morgan Securities LLC — EDGAR
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed. Market-wide feed: Planned sales (Form 144).
ETF Holders
2 ETFs hold SNTI
2 shown · $167.81K total exposure
# ETF Provider Weight $ Exposure ETF AUM As Of
1 VTI Vanguard Morningstar Total Stock Market ETF Vanguard 0.00% $115,164 — 2026-09-30
2 VXF Vanguard Extended Market ETF Vanguard 0.00% $52,645 — 2026-09-30
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.