ZYME · Insider Trading

Zymeworks Inc.

Every open-market purchase and sale reported by ZYME officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
15
code P
Sales
0
code S
Reporting Insiders
10
current holders
ZYME — Recent Form 4 Transactions (latest 2026-10-09)
FiledInsiderRole TypeSharesValue
2026-10-09 Adam Schayowitz EVP, Head of R&D MIXED +23,205 −$357.56K
2026-07-06 Mark Hollywood EVP & Chief Operating Officer A +939 +$20.86K
2026-05-15 Paul R Schneider EVP, General Counsel A +297,000 deriv. —
2026-04-10 Adam Schayowitz See Remarks A +193,000 deriv. —
2026-04-10 Scott Platshon EVP, Chief Business Officer A +193,000 deriv. —
2026-04-07 Kristin Stafford EVP, Chief Financial Officer A +347,000 deriv. —
2026-01-13 Brian N Cherry Director A +38,400 deriv. —
2026-01-13 Mark Hollywood EVP & Chief Operating Officer MIXED +11,546 −$138.76K
2026-01-12 Carlos Campoy Director A +19,200 deriv. —
2026-01-12 Alessandra Cesano Director A +19,200 deriv. —
2026-01-12 Paul Andrew Moore Chief Scientific Officer MIXED +8,106 −$216.76K
2026-01-12 Robert E Landry Director A +19,200 deriv. —
2026-01-12 Susan Mahony Director A +19,200 deriv. —
2026-01-12 Kelvin Neu Director A +19,200 deriv. —
2026-01-12 Kenneth Galbraith Chair & CEO MIXED +33,576 −$689.82K
2026-01-12 Gregory Austin Ciongoli Director A +19,200 deriv. —
2026-01-12 Jeffrey T L Smith EVP & Chief Medical Officer MIXED +8,356 −$211.09K
2026-01-07 Leone D Patterson EVP, Chief Bus & Fin Officer A +459 +$4.84K
2026-01-05 Kenneth Galbraith Chair & CEO MIXED +59,991 −$1.36M
2026-01-05 Jeffrey T L Smith EVP & Chief Medical Officer MIXED +9,462 −$264.47K
2026-01-05 Paul Andrew Moore Chief Scientific Officer MIXED +17,058 −$504.70K
2025-12-22 Kenneth Galbraith Chair & CEO MIXED +52,472 −$1.28M
2025-08-12 Robert E Landry Director A +62,000 deriv. —
2025-08-12 Gregory Austin Ciongoli Director A +415,000 +$4.99M
2025-06-27 Oleg Nodelman Director MIXED +10,172,878 −$25
2025-05-19 Oleg Nodelman Director Buy +110,842 +$1.27M
2025-04-18 Oleg Nodelman Director Buy +257,426 +$2.91M
2025-04-07 Oleg Nodelman Director Buy +634,416 +$7.25M
2025-04-02 Oleg Nodelman Director Buy +254,830 +$2.99M
2025-03-27 Oleg Nodelman Director Buy +194,698 +$2.45M
2025-03-24 Oleg Nodelman Director Buy +254,396 +$3.29M
2025-03-19 Oleg Nodelman Director Buy +456,926 +$5.73M
2025-03-13 Oleg Nodelman Director Buy +2,163,960 +$26.24M
2025-01-21 EcoR1 Capital, LLC Director Buy +141,429 +$1.96M
2025-01-15 EcoR1 Capital, LLC Director Buy +167,654 +$2.28M
2025-01-10 Jeffrey T L Smith EVP & Chief Medical Officer A +132,000 deriv. —
2025-01-10 Leone D Patterson EVP, Chief Bus & Fin Officer A +132,000 deriv. —
2025-01-10 EcoR1 Capital, LLC Director Buy +225,119 +$2.97M
2025-01-10 Paul Andrew Moore Chief Scientific Officer A +132,000 deriv. —
2025-01-10 Kenneth Galbraith Chair & CEO A +480,000 deriv. —
2025-01-06 Paul Andrew Moore Chief Scientific Officer MIXED +15,966 −$316.39K
2025-01-06 Jeffrey T L Smith EVP & Chief Medical Officer MIXED +8,890 −$165.81K
2025-01-06 Kenneth Galbraith Chair & CEO MIXED +57,041 −$855.02K
2025-01-02 EcoR1 Capital, LLC Director Buy +363,369 +$5.32M
2024-12-27 EcoR1 Capital, LLC Director Buy +130,309 +$1.88M
2024-12-26 EcoR1 Capital, LLC Director Buy +1,254,808 +$17.54M
2024-12-23 EcoR1 Capital, LLC 10%+ Owner Buy +5,086,521 deriv. —
2024-12-12 Derek John Michael Miller Director A +31,000 deriv. —
2024-12-12 Neil Gallagher Director A +31,000 deriv. —
2024-12-12 Nancy Davidson Director A +31,000 deriv. —
ZYME — Current Insider Holders
InsiderRole Shares HeldValue
Oleg Nodelman Director 22,970,388 $657.07M
EcoR1 Capital, LLC Director 15,720,161 $449.68M
Gregory Austin Ciongoli Director 493,500 $14.12M
Kenneth Galbraith Chair & CEO 257,266 $7.36M
Mark Hollywood EVP & Chief Operating Officer 133,852 $3.83M
Paul Andrew Moore Chief Scientific Officer 48,497 $1.39M
Adam Schayowitz EVP, Head of R&D 37,037 $1.06M
Jeffrey T L Smith EVP & Chief Medical Officer 36,018 $1.03M
Troy Cox Director 7,500 $214.54K
Leone D Patterson EVP, Chief Bus & Fin Officer 459 $13.13K
ZYME Insider Trading FAQ
Who are the insiders at ZYME?
10 officers, directors and 10%+ beneficial owners currently report holdings in ZYME via SEC Form 4.
Are ZYME insiders buying or selling?
Across the 50 most recent Form 4 filings for ZYME, 15 were open-market purchases (code P) and 0 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is ZYME insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent ZYME filing is dated 2026-10-09.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the ZYME quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.