Edward T Mathers

CIK 1328625 · EVP, Corporate Dev. & Venture · last filed 2026-08-11

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$475.49M

Companies

19

Total Filings

84

Lifetime Open-Market Net

$47.23M

Filer Profile

Reported Address
104 5TH AVENUE
19TH FLOOR
NEW YORK, NY 10011
Related Filers
Inozyme Pharma, Inc. — 6 joint filings, latest 2024-06-20
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
OKUR Director 15,310 $3.10 $47.5K $0 8 2026-08-11
MBX Director 1,023,103 $59.02 $60.38M $8.00M 4 2026-06-05
TRVI Director 948,948 $15.90 $15.09M $0 9 2026-06-04
RYTM Director 21,168 $104.71 $2.22M $0 14 2026-03-16
KRRO 10%+ Owner 1,297,893 $13.81 $17.92M $3.30M 2 2026-03-12
SGP 10%+ Owner 6,035,038 $27.52 $166.08M $15.00M 1 2026-02-11
NeueHealth, Inc. (BHG) Delisted Director 488,982 $16.35 $7.99M -$24.5K 6 2025-10-06
SNTI Director $0.31 $0 5 2025-06-27
NeueHealth, Inc. (NEUE) Delisted 10%+ Owner $6.75 $0 2 2024-10-03
Inozyme Pharma, Inc. (INZY) Delisted Director $4.00 $0 5 2024-06-20
SVRA 10%+ Owner 24,471,264 $5.30 $129.70M $1000.0K 1 2023-07-19
SYNLOGIC, INC. (SYBX) Delisted Director $0.69 $0 8 2023-06-26
OnKure Therapeutics, Inc. (RPHM) Delisted Director $18.20 $0 3 2023-06-08
Akouos, Inc. (AKUS) Delisted Director $13.29 $0 3 2022-12-02
MIRM Director $98.22 $0 3 2022-06-06
GLUE 10%+ Owner 5,973,296 $14.07 $84.04M $19.95M 1 2021-06-30
Ra Pharmaceuticals, Inc. (RARX) Delisted Director $0 4 2020-04-03
SYNLOGIC, INC. (MIRN) Delisted Director $0 1 2016-09-06
MEDI EVP, Corporate Dev. & Venture $33.38 $0 2 2007-06-19

Recent Filings · Page 5 of 9

84 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2023-06-15 Inozyme Pharma, Inc. (INZY) Delisted Grant (A) $0 EDGAR
2023-06-08 OnKure Therapeutics, Inc. (RPHM) Delisted Grant (A) $0 EDGAR
2023-03-06 RYTM Other (J) +5,771 $0 EDGAR
2022-12-02 Akouos, Inc. (AKUS) Delisted Disp (D) $0 EDGAR
2022-10-19 NeueHealth, Inc. (BHG) Delisted Buy (P) $0 EDGAR
2022-07-15 SNTI Grant (A) $0 EDGAR
2022-06-27 Akouos, Inc. (AKUS) Delisted Grant (A) $0 EDGAR
2022-06-23 TRVI Grant (A) $0 EDGAR
2022-06-14 Inozyme Pharma, Inc. (INZY) Delisted Grant (A) $0 EDGAR
2022-06-13 SYNLOGIC, INC. (SYBX) Delisted Grant (A) $0 EDGAR
Showing 4150 of 84
Page 5 of 9
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.