Baker Brothers Life Sciences LP

CIK 1363364 · last filed 2026-06-18

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$3.48B

Companies

23

Total Filings

92

Lifetime Open-Market Net

$5.81B

Filer Profile

Reported Address
860 WASHINGTON STREET
3RD FLOOR
NEW YORK, NY 10014
Phone
(212) 339-5600
State of Incorporation
DE
Related Filers
BAKER BROS. ADVISORS LP — 525 joint filings, latest 2026-08-11
JULIAN BAKER — 525 joint filings, latest 2026-08-11
667, L.P. — 521 joint filings, latest 2026-08-11
FELIX BAKER — 520 joint filings, latest 2026-08-11
Baker Bros. Advisors (GP) LLC — 495 joint filings, latest 2026-08-11
14159, L.P. — 216 joint filings, latest 2019-10-03
Baker Bros. Investments, L.P. — 82 joint filings, latest 2019-10-03
Baker/Tisch Investments, LP — 82 joint filings, latest 2019-10-03
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
MDGL Director 1,948,876 $534.49 $1.04B $221.65M 2 2026-06-18
INCY Director 3,098,808 $121.47 $376.41M $390.15M 15 2026-01-05
KYMR Director 7,955,916 $114.96 $914.61M $1.03B 1 2025-12-11
PRLD Director $4.59 $0 2 2025-06-13
REPL Director $12.92 $0 1 2025-03-07
IGM Biosciences, Inc. (IGMS) Delisted Director 3,759,462 $1.27 $4.77M $0 5 2024-10-02
VTVT Director $31.97 $0 1 2024-06-27
ACAD Director 39,452,627 $27.83 $1.10B $900.00M 4 2024-05-31
BCYC Director $3.86 $0 1 2024-05-29
TCRX Director 104,698 $0.32 $33.5K $128.25M 3 2024-04-23
BeOne Medicines Ltd. (BGNE) Delisted Director 93,418 $184.71 $17.26M -$1.19B 3 2023-11-14
Neurogene Inc. (NLTX) Delisted Director 116,457 $13.96 $1.63M $160.87M 2 2023-08-17
KOD Director 1,143,396 $32.89 $37.61M $1.08B 4 2022-07-05
DBVT Director 1,341,390 $11.85 $15.90M $0 1 2022-06-13
Spyre Therapeutics, Inc. (AGLE) Delisted Director $12.01 $0 1 2021-06-10
Talis Biomedical Corp (TLIS) Delisted Director 466,878 $2.84 $1.33M $600.00M 1 2021-02-19
KNSA Director $76.27 $0 1 2020-05-18
GENOMIC HEALTH INC (GHDX) Delisted Director 166,122 -$403.77M 11 2019-04-10
Neurogene Inc. (AQXP) Delisted Director $0 1 2018-05-09
Seagen Inc. (SGEN) Delisted Director 44,865,178 $228.74 $10.26B $2.16B 6 2018-05-02
Aceragen, Inc. (IDRA) Delisted Director 242,126 $7.22 $1.75M $0 8 2018-04-04
XOMA Royalty Corp (XOMA) Delisted Director 23,372 $40.17 $938.9K -$62.10M 5 2015-07-23
SYNAGEVA BIOPHARMA CORP (GEVA) Delisted Director 144,482 $778.06M 3 2015-01-09

Recent Filings · Page 10 of 10

92 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2013-01-08 SYNAGEVA BIOPHARMA CORP (GEVA) Delisted Buy (P) +3,438,880 $163.45M EDGAR
2012-11-23 GENOMIC HEALTH INC (GHDX) Delisted Buy (P) +1,375,800 $36.91M EDGAR
Showing 9192 of 92
Page 10 of 10
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.