Baker Bros. Advisors (GP) LLC

CIK 1580575 · last filed 2026-06-05

Baker Bros. Advisors (GP) LLC is a corporate insider who has filed 65 SEC Form 4 insider transactions across 20 companies since 2014. The most recent filing, for DNLI, was dated Jun 5, 2026. Across all open-market trades the lifetime net is −$227.6M, making them a net seller over the disclosed history. Current disclosed insider exposure totals $5.33B across reported positions.

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$5.33B

Companies

20

Total Filings

65

Lifetime Open-Market Net

-$227.62M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
DNLI Director 3,422,366 $21.66 $74.13M $0 1 2026-06-05
TRDA 10%+ Owner 4,541,670 $6.46 $29.34M $6.54M 2 2025-11-12
CELC 10%+ Owner 7,211,484 $88.55 $638.58M $38.29M 1 2025-09-10
KOD Director 15,142,074 $34.06 $515.74M $402.01M 6 2025-07-02
INCY Director 28,468,279 $108.53 $3.09B $1.13B 12 2025-06-12
KNSA Director 138,912 $51.89 $7.21M $0 2 2024-06-07
KYMR Director $86.20 $0 1 2024-04-01
MDGL Director 1,668,553 $480.77 $802.19M $284.55M 4 2023-12-14
IGM Biosciences, Inc. (IGMS) Delisted Director 274,006 $1.27 $348.0K $0 2 2023-07-05
BeOne Medicines Ltd. (BGNE) Delisted Director 93,414 $184.71 $17.25M $0 1 2023-06-20
PRLD Director 876,061 $4.49 $3.93M $0 2 2023-05-24
TCRX Director 253,327 $0.91 $231.1K $15.35M 1 2022-05-12
Seagen Inc. (SGEN) Delisted Director 4,103,889 $228.74 $938.72M -$2.33B 10 2021-12-02
ACAD Director 3,566,625 $21.09 $75.22M $201.91M 1 2020-03-18
GENOMIC HEALTH INC (GHDX) Delisted Director 1,333,275 -$256.29M 8 2019-04-03
Invitae Corp (NVTA) Delisted 10%+ Owner 845,858 $0.09 $75.4K $20.00M 1 2018-03-29
RYTM 1,081,051 $88.38 $95.54M $60.18M 1 2017-10-06
Aceragen, Inc. (IDRA) Delisted Director 1,017,950 $7.22 $7.35M $0 3 2017-06-08
Mirati Therapeutics, Inc. (MRTX) Delisted 10%+ Owner 30,140 $58.70 $1.77M $40.39M 3 2016-06-09
Neurogene Inc. (AQXP) Delisted 10%+ Owner 6,376,467 $160.86M 2 2016-01-20

Recent Filings

65 filings
Form 4 transactions across all companies, newest first.
Filed Symbol Action Net Shares Net $ Link
2026-06-05 DNLI Grant (A) +76,896 $0 EDGAR
2025-11-12 TRDA Buy (P) +712,176 $5.41M EDGAR
2025-09-10 CELC Buy (P) +680,400 $38.29M EDGAR
2025-07-02 KOD Grant (A) $0 EDGAR
2025-06-12 INCY Grant (A) +30,216 $0 EDGAR
2024-06-07 KNSA Grant (A) +76,152 $0 EDGAR
2024-04-01 KYMR Grant (A) $0 EDGAR
2023-12-14 MDGL Buy (P) +207,468 $45.29M EDGAR
2023-11-24 Exer (X) +8,465,396 $847
2023-11-21 MDGL Buy (P) +402,474 $71.68M EDGAR
Showing 110 of 65
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Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.