Baker Bros. Advisors (GP) LLC
CIK 1580575 · last filed 2026-06-25
Baker Bros. Advisors (GP) LLC is a corporate insider who has filed 66 SEC Form 4 insider transactions across 20 companies since 2014. The most recent filing, for KYMR, was dated Jun 25, 2026. Across all open-market trades the lifetime net is −$227.6M, making them a net seller over the disclosed history. Current disclosed insider exposure totals $6.19B across reported positions.
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
$6.19B
20
66
-$227.62M
Holdings By Company
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| KYMR | Director | — | $106.89 | — | $0 | 2 | 2026-06-25 |
| DNLI | Director | 3,422,366 | $23.98 | $82.07M | $0 | 1 | 2026-06-05 |
| TRDA | 10%+ Owner | 4,541,670 | $5.84 | $26.52M | $6.54M | 2 | 2025-11-12 |
| CELC | 10%+ Owner | 7,211,484 | $82.54 | $595.24M | $38.29M | 1 | 2025-09-10 |
| KOD | Director | 15,142,074 | $39.94 | $604.77M | $402.01M | 6 | 2025-07-02 |
| INCY | Director | 28,468,279 | $131.75 | $3.75B | $1.13B | 12 | 2025-06-12 |
| KNSA | Director | 138,912 | $80.05 | $11.12M | $0 | 2 | 2024-06-07 |
| MDGL | Director | 1,668,553 | $540.18 | $901.32M | $284.55M | 4 | 2023-12-14 |
| IGM Biosciences, Inc. (IGMS) Delisted | Director | 274,006 | $1.27 | $348.0K | $0 | 2 | 2023-07-05 |
| BeOne Medicines Ltd. (BGNE) Delisted | Director | 93,414 | $184.71 | $17.25M | $0 | 1 | 2023-06-20 |
| PRLD | Director | 876,061 | $4.68 | $4.10M | $0 | 2 | 2023-05-24 |
| TCRX | Director | 253,327 | $0.77 | $195.4K | $15.35M | 1 | 2022-05-12 |
| Seagen Inc. (SGEN) Delisted | Director | 4,103,889 | $228.74 | $938.72M | -$2.33B | 10 | 2021-12-02 |
| ACAD | Director | 3,566,625 | $26.04 | $92.86M | $201.91M | 1 | 2020-03-18 |
| GENOMIC HEALTH INC (GHDX) Delisted | Director | 1,333,275 | — | — | -$256.29M | 8 | 2019-04-03 |
| Invitae Corp (NVTA) Delisted | 10%+ Owner | 845,858 | $0.09 | $75.4K | $20.00M | 1 | 2018-03-29 |
| RYTM | 1,081,051 | $107.83 | $116.56M | $60.18M | 1 | 2017-10-06 | |
| Aceragen, Inc. (IDRA) Delisted | Director | 59,879 | $7.22 | $432.6K | $0 | 3 | 2017-06-08 |
| Mirati Therapeutics, Inc. (MRTX) Delisted | 10%+ Owner | 30,140 | $58.70 | $1.77M | $40.39M | 3 | 2016-06-09 |
| Neurogene Inc. (AQXP) Delisted | 10%+ Owner | 6,376,467 | — | — | $160.86M | 2 | 2016-01-20 |
Recent Filings
66 filings| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2026-06-25 | KYMR | Grant (A) | — | $0 | EDGAR |
| 2026-06-05 | DNLI | Grant (A) | +76,896 | $0 | EDGAR |
| 2025-11-12 | TRDA | Buy (P) | +712,176 | $5.41M | EDGAR |
| 2025-09-10 | CELC | Buy (P) | +680,400 | $38.29M | EDGAR |
| 2025-07-02 | KOD | Grant (A) | — | $0 | EDGAR |
| 2025-06-12 | INCY | Grant (A) | +30,216 | $0 | EDGAR |
| 2024-06-07 | KNSA | Grant (A) | +76,152 | $0 | EDGAR |
| 2024-04-01 | KYMR | Grant (A) | — | $0 | EDGAR |
| 2023-12-14 | MDGL | Buy (P) | +207,468 | $45.29M | EDGAR |
| 2023-11-24 | — | Exer (X) | +8,465,396 | $847 |
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.