Baker Bros. Advisors (GP) LLC
CIK 1580575 · last filed 2026-06-25
Baker Bros. Advisors (GP) LLC is a corporate insider who has filed 66 SEC Form 4 insider transactions across 20 companies since 2014. The most recent filing, for KYMR, was dated Jun 25, 2026. Across all open-market trades the lifetime net is −$227.6M, making them a net seller over the disclosed history. Current disclosed insider exposure totals $5.78B across reported positions. The firm reports its address in New York, NY. 555 SEC filings were submitted jointly with BAKER BROS. ADVISORS LP.
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
$5.78B
20
66
-$227.62M
Filer Profile
3RD FLOOR
NEW YORK, NY 10014
Holdings By Company
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| KYMR | Director | — | $114.96 | — | $0 | 2 | 2026-06-25 |
| DNLI | Director | 3,422,366 | $21.09 | $72.18M | $0 | 1 | 2026-06-05 |
| TRDA | 10%+ Owner | 4,541,670 | $6.80 | $30.88M | $6.54M | 2 | 2025-11-12 |
| CELC | 10%+ Owner | 7,211,484 | $83.45 | $601.80M | $38.29M | 1 | 2025-09-10 |
| KOD | Director | 15,142,074 | $32.89 | $498.02M | $402.01M | 6 | 2025-07-02 |
| INCY | Director | 28,468,279 | $121.47 | $3.46B | $1.13B | 12 | 2025-06-12 |
| KNSA | Director | 138,912 | $76.27 | $10.59M | $0 | 2 | 2024-06-07 |
| MDGL | Director | 1,668,553 | $534.49 | $891.82M | $284.55M | 4 | 2023-12-14 |
| IGM Biosciences, Inc. (IGMS) Delisted | Director | 274,006 | $1.27 | $348.0K | $0 | 2 | 2023-07-05 |
| BeOne Medicines Ltd. (BGNE) Delisted | Director | 93,414 | $184.71 | $17.25M | $0 | 1 | 2023-06-20 |
| PRLD | Director | 876,061 | $4.59 | $4.02M | $0 | 2 | 2023-05-24 |
| TCRX | Director | 253,327 | $0.32 | $81.2K | $15.35M | 1 | 2022-05-12 |
| Seagen Inc. (SGEN) Delisted | Director | 4,103,889 | $228.74 | $938.72M | -$2.33B | 10 | 2021-12-02 |
| ACAD | Director | 3,566,625 | $27.83 | $99.26M | $201.91M | 1 | 2020-03-18 |
| GENOMIC HEALTH INC (GHDX) Delisted | Director | 1,333,275 | — | — | -$256.29M | 8 | 2019-04-03 |
| Invitae Corp (NVTA) Delisted | 10%+ Owner | 845,858 | $0.09 | $75.4K | $20.00M | 1 | 2018-03-29 |
| RYTM | 1,081,051 | $104.71 | $113.20M | $60.18M | 1 | 2017-10-06 | |
| Aceragen, Inc. (IDRA) Delisted | Director | 59,879 | $7.22 | $432.6K | $0 | 3 | 2017-06-08 |
| Mirati Therapeutics, Inc. (MRTX) Delisted | 10%+ Owner | 30,140 | $58.70 | $1.77M | $40.39M | 3 | 2016-06-09 |
| Neurogene Inc. (AQXP) Delisted | 10%+ Owner | 6,376,467 | — | — | $160.86M | 2 | 2016-01-20 |
Recent Filings
66 filings| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2026-06-25 | KYMR | Grant (A) | — | $0 | EDGAR |
| 2026-06-05 | DNLI | Grant (A) | +76,896 | $0 | EDGAR |
| 2025-11-12 | TRDA | Buy (P) | +712,176 | $5.41M | EDGAR |
| 2025-09-10 | CELC | Buy (P) | +680,400 | $38.29M | EDGAR |
| 2025-07-02 | KOD | Grant (A) | — | $0 | EDGAR |
| 2025-06-12 | INCY | Grant (A) | +30,216 | $0 | EDGAR |
| 2024-06-07 | KNSA | Grant (A) | +76,152 | $0 | EDGAR |
| 2024-04-01 | KYMR | Grant (A) | — | $0 | EDGAR |
| 2023-12-14 | MDGL | Buy (P) | +207,468 | $45.29M | EDGAR |
| 2023-11-24 | — | Exer (X) | +8,465,396 | $847 |
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.