PRAX · Insider Trading
Praxis Precision Medicines, Inc. Common Stock
Every open-market purchase and sale reported by PRAX officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.
| Filed | Insider | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-08 | Marcio Souza | Chief Executive Officer | G | −23,121 | — |
| 2026-06-26 | Jill DeSimone | Director | MIXED | — | −$2.79M |
| 2026-06-12 | Merit Ester Cudkowicz | Director | A | +1,371 | — |
| 2026-06-12 | Stuart A Arbuckle | Director | A | +1,371 | — |
| 2026-06-12 | Gregory Norden | Director | A | +1,371 | — |
| 2026-06-12 | Jeffrey Chodakewitz | Director | A | +1,371 | — |
| 2026-06-12 | William D Young | Director | A | +1,371 | — |
| 2026-06-12 | Jeffrey B Kindler | Director | A | +1,371 | — |
| 2026-06-12 | Dean J Mitchell | Director | A | +1,371 | — |
| 2026-06-12 | Jill DeSimone | Director | A | +1,371 | — |
| 2026-05-19 | Lauren Mastrocola | Principal Accounting Officer | A | +127 | +$21.33K |
| 2026-05-19 | Megan Sniecinski | Chief Operating Officer | A | +89 | +$14.95K |
| 2026-05-19 | Timothy Edwin Kelly | Chief Financial Officer | A | +121 | +$20.32K |
| 2026-05-19 | Alex Nemiroff | General Counsel and Secretary | A | +78 | +$13.10K |
| 2026-05-19 | Marcio Souza | Chief Executive Officer | A | +126 | +$21.16K |
| 2026-02-10 | Stuart A Arbuckle | Director | A | +1,166 | — |
| 2026-02-10 | Jeffrey B Kindler | Director | A | +1,166 | — |
| 2026-01-13 | Megan Sniecinski | Chief Operating Officer | F | −885 | −$244.03K |
| 2026-01-13 | Alex Nemiroff | General Counsel and Secretary | F | −768 | −$211.77K |
| 2026-01-13 | Lauren Mastrocola | Principal Accounting Officer | F | −344 | −$94.85K |
| 2026-01-13 | Timothy Edwin Kelly | Chief Financial Officer | F | −943 | −$260.02K |
| 2026-01-12 | Timothy Edwin Kelly | Chief Financial Officer | MIXED | +7,465 | −$385.08K |
| 2026-01-12 | Marcio Souza | Chief Executive Officer | MIXED | +23,388 | −$1.23M |
| 2026-01-12 | Alex Nemiroff | General Counsel and Secretary | MIXED | +5,958 | −$264.51K |
| 2026-01-12 | Megan Sniecinski | Chief Operating Officer | MIXED | +8,538 | −$313.55K |
| 2026-01-12 | Lauren Mastrocola | Principal Accounting Officer | MIXED | +3,383 | −$105.86K |
| 2026-01-09 | Alex Nemiroff | General Counsel and Secretary | F | −89 | −$26.04K |
| 2026-01-09 | Marcio Souza | Chief Executive Officer | F | −405 | −$118.52K |
| 2026-01-09 | Lauren Mastrocola | Principal Accounting Officer | F | −35 | −$10.24K |
| 2026-01-09 | Timothy Edwin Kelly | Chief Financial Officer | F | −139 | −$40.68K |
| 2025-12-31 | Marcio Souza | Chief Executive Officer | G | −400 | — |
| 2025-11-21 | Timothy Edwin Kelly | Chief Financial Officer | A | +384 | +$12.14K |
| 2025-11-21 | Alex Nemiroff | General Counsel and Secretary | MIXED | — | −$3.00M |
| 2025-11-21 | Lauren Mastrocola | Principal Accounting Officer | MIXED | — | −$1.78M |
| 2025-10-17 | Adage Capital Management, L.P. | 10%+ Owner | Sell | +941,730 | +$99.59M |
| 2025-09-25 | Dean J Mitchell | Director | M | +12,251 | +$483.99K |
| 2025-06-27 | Jeffrey Chodakewitz | Director | A | +10,520 deriv. | — |
| 2025-06-27 | Jill DeSimone | Director | A | +10,520 deriv. | — |
| 2025-06-27 | Merit Ester Cudkowicz | Director | A | +10,520 deriv. | — |
| 2025-06-27 | Gregory Norden | Director | A | +10,520 deriv. | — |
| 2025-06-27 | Dean J Mitchell | Director | A | +10,520 deriv. | — |
| 2025-06-27 | William D Young | Director | A | +10,520 deriv. | — |
| 2025-05-19 | Timothy Edwin Kelly | Chief Financial Officer | A | +249 | +$7.85K |
| 2025-05-19 | Marcio Souza | Chief Executive Officer | A | +348 | +$10.97K |
| 2025-02-14 | Lauren Mastrocola | Principal Accounting Officer | F | −40 | −$3.42K |
| 2025-02-14 | Marcio Souza | Chief Executive Officer | F | −401 | −$34.25K |
| 2025-02-14 | Alex Nemiroff | General Counsel and Secretary | F | −51 | −$4.36K |
| 2025-01-14 | Lauren Mastrocola | Principal Accounting Officer | MIXED | +4,610 | −$24.63K |
| 2025-01-14 | Marcio Souza | Chief Executive Officer | A | +37,500 | — |
| 2025-01-14 | Timothy Edwin Kelly | Chief Financial Officer | MIXED | +11,824 | −$42.69K |
| Insider | Role | Shares Held | Value |
|---|---|---|---|
| Adage Capital Management, L.P. | 10%+ Owner | 2,359,116 | $570.34M |
| Marcio Souza | Chief Executive Officer | 56,495 | $13.66M |
| Timothy Edwin Kelly | Chief Financial Officer | 31,167 | $7.53M |
| Megan Sniecinski | Chief Operating Officer | 28,664 | $6.93M |
| Alex Nemiroff | General Counsel and Secretary | 26,010 | $6.29M |
| Dean J Mitchell | Director | 18,622 | $4.50M |
| Lauren Mastrocola | Principal Accounting Officer | 13,572 | $3.28M |
| Jill DeSimone | Director | 4,957 | $1.20M |
| William D Young | Director | 3,269 | $790.31K |
| Jeffrey B Kindler | Director | 2,537 | $613.35K |
| Stuart A Arbuckle | Director | 2,537 | $613.35K |
| Gregory Norden | Director | 1,559 | $376.90K |
| Jeffrey Chodakewitz | Director | 1,371 | $331.45K |
| Merit Ester Cudkowicz | Director | 1,371 | $331.45K |
Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.
Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.
Full filing history and per-insider positions are on the PRAX quote page; the site-wide leaderboard is on the insider transactions hub.
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.