PYXS (Pyxis Oncology, Inc. Common Stock)

Insider Trading Activity

Every open-market purchase and sale reported by PYXS officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Form 4 Filings
50
most recent
Open-Market Buys
7
code P
Sales
1
code S
Reporting Insiders
15
current holders
PYXS — Recent Form 4 Transactions (latest 2026-08-20)
FiledInsiderRole TypeSharesValue
2026-08-20 Jakob Dupont Director A
2026-08-14 Thomas Civik Interim CEO A
2026-07-02 Jakob Dupont Director MIXED
2026-03-25 RACHEL HUMPHREY Director A
2026-03-25 Santhosh Palani Director A
2026-03-25 Michael A Metzger Director A
2026-03-25 Freda C Lewis-Hall Director A
2026-03-25 RACHEL HUMPHREY Director Sell
2026-03-25 JOHN L FLAVIN Director A
2026-03-25 Darren S Cline Director A
2026-03-25 Jitendra Wadhane Prin Fin & Acct Officer A
2026-03-25 Jakob Dupont Director A
2026-02-05 Thomas Civik Interim CEO A
2025-04-02 Jitendra Wadhane SVP, Chief Accounting Officer A
2025-04-02 Freda C Lewis-Hall Director A
2025-04-02 RACHEL HUMPHREY Director A
2025-04-02 Santhosh Palani Director A
2025-04-02 Michael A Metzger Director A
2025-04-02 Lara Sullivan President ,CEO & CMO A
2025-04-02 Darren S Cline Director A
2025-04-02 Jakob Dupont Director A
2025-04-02 Thomas Civik Director A
2025-04-02 Pamela Ann Connealy CFO & COO A
2025-04-02 JOHN L FLAVIN Director A
2024-12-23 Pamela Ann Connealy CFO & COO A
2024-12-23 Lara Sullivan Chief Executive Officer A
2024-12-23 Jitendra Wadhane SVP, Chief Accounting Officer A
2024-11-27 Pamela Ann Connealy CFO & COO Buy
2024-06-10 Michael A Metzger Director A
2024-06-07 Santhosh Palani Director A
2024-03-28 Lara Sullivan Chief Executive Officer A
2024-03-28 Thomas Civik Director A
2024-03-28 JOHN L FLAVIN Director A
2024-03-28 RACHEL HUMPHREY Director A
2024-03-28 Freda C Lewis-Hall Director A
2024-03-28 Jakob Dupont Director A
2024-03-28 Pamela Ann Connealy CFO & COO A
2024-03-28 Darren S Cline Director A
2024-03-28 Jitendra Wadhane SVP, Chief Accounting Officer A
2024-03-13 Santhosh Palani Director A
2023-12-29 Ken Kobayashi Chief Medical Officer A
2023-11-30 Pamela Ann Connealy CFO and COO F
2023-11-17 Jitendra Wadhane Chief Accounting Officer A
2023-09-28 Pamela Ann Connealy CFO and COO Buy
2023-09-27 Pamela Ann Connealy CFO and COO Buy
2023-09-27 Jitendra Wadhane Chief Accounting Officer Buy
2023-09-26 Jakob Dupont Director A
2023-09-25 Pamela Ann Connealy CFO and COO Buy
2023-09-25 Jitendra Wadhane Chief Accounting Officer Buy
2023-09-22 Pamela Ann Connealy CFO and COO Buy
PYXS — Current Insider Holders
InsiderRole Shares HeldValue
10%+ Owner 7,032,770
2,742,338
President ,CEO & CMO 2,412,423
CFO & COO 2,226,036
Chief Medical Officer 730,345
Director 668,854
Prin Fin & Acct Officer 512,882
Director 413,015
Director 251,405
Director 241,405
Interim CEO 221,886
Director 95,405
Director 66,831
Director 38,741
Director 6,000
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the PYXS quote page; the site-wide leaderboard is on the insider transactions hub.