PYXS · Insider Trading

Pyxis Oncology, Inc. Common Stock

Every open-market purchase and sale reported by PYXS officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
6
code P
Sales
1
code S
Reporting Insiders
11
current holders
PYXS — Recent Form 4 Transactions (latest 2026-10-09)
FiledInsiderRole TypeSharesValue
2026-10-09 GordonMD Long Biased Master Fund LP 10%+ Owner Buy +28,688,000 deriv. —
2026-10-02 GordonMD Global Investments LP 10%+ Owner Buy +22,068,000 —
2026-09-08 Thomas Civik CEO & Chairman of the Board A +2,503,050 deriv. —
2026-08-20 Jakob Dupont Director A +46,000 deriv. —
2026-08-14 Thomas Civik Interim CEO A +250,956 deriv. —
2026-07-02 Jakob Dupont Director MIXED — −$51.10K
2026-03-25 Rachel Humphrey Director A +45,867 deriv. —
2026-03-25 Santhosh Palani Director A +45,867 deriv. —
2026-03-25 Michael A Metzger Director A +45,867 deriv. —
2026-03-25 Freda C Lewis-Hall Director A +45,867 deriv. —
2026-03-25 Rachel Humphrey Director Sell −15,496 −$15.92K
2026-03-25 John L Flavin Director A +45,867 deriv. —
2026-03-25 Darren S Cline Director A +45,867 deriv. —
2026-03-25 Jitendra Wadhane Prin Fin & Acct Officer A +109,461 —
2026-03-25 Jakob Dupont Director A +45,867 deriv. —
2026-02-05 Thomas Civik Interim CEO A +690,131 deriv. —
2025-04-02 Jitendra Wadhane SVP, Chief Accounting Officer A +263,782 deriv. —
2025-04-02 Freda C Lewis-Hall Director A +36,979 deriv. —
2025-04-02 Rachel Humphrey Director A +36,979 deriv. —
2025-04-02 Santhosh Palani Director A +36,979 deriv. —
2025-04-02 Michael A Metzger Director A +36,979 deriv. —
2025-04-02 Lara Sullivan President ,CEO & CMO A +918,308 deriv. —
2025-04-02 Darren S Cline Director A +36,979 deriv. —
2025-04-02 Jakob Dupont Director A +36,979 deriv. —
2025-04-02 Thomas Civik Director A +36,979 deriv. —
2025-04-02 Pamela Ann Connealy CFO & COO A +414,163 deriv. —
2025-04-02 John L Flavin Director A +36,979 deriv. —
2024-12-23 Pamela Ann Connealy CFO & COO A +310,000 deriv. —
2024-12-23 Lara Sullivan Chief Executive Officer A +1,135,000 deriv. —
2024-12-23 Jitendra Wadhane SVP, Chief Accounting Officer A +150,000 deriv. —
2024-11-27 Pamela Ann Connealy CFO & COO Buy +88,850 +$174.36K
2024-06-10 Michael A Metzger Director A +70,683 deriv. —
2024-06-07 Santhosh Palani Director A +6,000 —
2024-03-28 Lara Sullivan Chief Executive Officer A +1,071,242 deriv. —
2024-03-28 Thomas Civik Director A +44,024 deriv. —
2024-03-28 John L Flavin Director A +35,219 —
2024-03-28 Rachel Humphrey Director A +38,741 —
2024-03-28 Freda C Lewis-Hall Director A +35,219 —
2024-03-28 Jakob Dupont Director A +38,741 —
2024-03-28 Pamela Ann Connealy CFO & COO A +328,710 —
2024-03-28 Darren S Cline Director A +35,219 —
2024-03-28 Jitendra Wadhane SVP, Chief Accounting Officer A +131,484 —
2024-03-13 Santhosh Palani Director A +69,760 deriv. —
2023-12-29 Ken Kobayashi Chief Medical Officer A +554,392 deriv. —
2023-11-30 Pamela Ann Connealy CFO and COO F −36,949 −$51.73K
2023-11-17 Jitendra Wadhane Chief Accounting Officer A +40,000 —
2023-09-28 Pamela Ann Connealy CFO and COO Buy +8,000 +$14.96K
2023-09-27 Pamela Ann Connealy CFO and COO Buy +6,426 +$11.87K
2023-09-27 Jitendra Wadhane Chief Accounting Officer Buy +2,500 +$4.67K
2023-09-26 Jakob Dupont Director A +392,461 deriv. —
PYXS — Current Insider Holders
InsiderRole Shares HeldValue
GordonMD Global Investments LP 10%+ Owner 15,541,909 $26.58M
Lara Sullivan President ,CEO & CMO 2,412,423 $4.13M
Pamela Ann Connealy CFO & COO 2,226,036 $3.81M
Jitendra Wadhane Prin Fin & Acct Officer 512,882 $877.03K
John L Flavin Director 413,015 $706.26K
Darren S Cline Director 251,405 $429.90K
Freda C Lewis-Hall Director 241,405 $412.80K
Thomas Civik CEO & Chairman of the Board 221,886 $379.43K
Rachel Humphrey Director 95,405 $163.14K
Jakob Dupont Director 38,741 $66.25K
Santhosh Palani Director 6,000 $10.26K
PYXS Insider Trading FAQ
Who are the insiders at PYXS?
11 officers, directors and 10%+ beneficial owners currently report holdings in PYXS via SEC Form 4.
Are PYXS insiders buying or selling?
Across the 50 most recent Form 4 filings for PYXS, 6 were open-market purchases (code P) and 1 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is PYXS insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent PYXS filing is dated 2026-10-09.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the PYXS quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.