Bain Capital Life Sciences Investors, LLC — 13F Holdings & Portfolio

CIK 1703031 · latest 13F-HR filed 2026-08-14

Bain Capital Life Sciences Investors, LLC manages $1.68B in 13F-reported U.S. long-equity assets across 21 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are KLRA (29.58%), HTFL (14.74%), NAMS (7.67%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 2 new positions, exited 1, added to 11, and trimmed 6.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

Filer Information
Address
200 CLARENDON STREET
BOSTON, MA 02116
Phone
(617) 516-2878
Filing Manager
Bain Capital Life Sciences Investors, LLC
Boston, MA
Signatory
Adam Koppel
Partner of Bain Capital Life Sciences Investors, LLC
Loading holdings…
AUM

$1.68B

Long-equity book

Holdings

21

Distinct positions

Period

2026-06-30

Filed 2026-08-14

Q/Q Activity

+2 / −1 / ↑11 / ↓6

vs 2026-03-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • ALKERMES PLC$80.0M +370.7%
  • CABALETTA BIO INC$27.6M +106.0%
  • SOLID BIOSCIENCES INC$27.4M +38.7%
  • PHARVARIS N V$16.9M +22.4%
  • C4 THERAPEUTICS INC$14.6M +77.6%
Show all 11 →

Top Trims

  • NEWAMSTERDAM PHARMA COMPANY-$104.9M -44.8%
  • OLEMA PHARMACEUTICALS INC-$22.8M -20.5%
  • RAPID MICRO BIOSYSTEMS INC-$4.6M -23.8%
  • UPSTREAM BIO INC-$3.6M -46.7%
  • ANNEXON INC-$3.5M -12.3%
Show all 6 →

New Positions

  • KAILERA THERAPEUTICS INC$497.5M
  • HEMAB THERAPEUTICS HOLDINGS INC$60.6M
Show all 2 →

Exited Positions

  • CENTESSA PHARMACEUTICALS$25.2M
Show all 1 →
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 KAILERA THERAPEUTICS INC KLRA 482931102 $497.5M 29.58% 22,583,268 SH
2 HEARTFLOW INC HTFL 42238D107 $247.9M 14.74% 8,448,158 SH
3 NEWAMSTERDAM PHARMA COMPANY NAMS N62509109 $129.0M 7.67% 3,806,566 SH
4 SAVARA INC SVRA 805111101 $108.4M 6.45% 17,600,621 SH
5 ALKERMES PLC ALKS G01767105 $101.5M 6.04% 1,937,938 SH
6 SOLID BIOSCIENCES INC SLDB 83422E204 $98.0M 5.83% 9,808,819 SH
7 PHARVARIS N V PHVS N69605108 $92.5M 5.50% 2,675,509 SH
8 OLEMA PHARMACEUTICALS INC OLMA 68062P106 $88.6M 5.27% 7,085,249 SH
9 HEMAB THERAPEUTICS HOLDINGS INC COAG 423494103 $60.6M 3.60% 1,650,000 SH
10 CABALETTA BIO INC CABA 12674W109 $53.6M 3.19% 17,241,445 SH
11 X4 PHARMACEUTICALS INC XFOR 98420X202 $37.2M 2.21% 7,967,454 SH
12 DIANTHUS THERAPEUTICS INC DNTH 252828108 $35.3M 2.10% 362,470 SH
13 C4 THERAPEUTICS INC CCCC 12529R107 $33.5M 1.99% 7,171,910 SH
14 KYVERNA THERAPEUTICS INC KYTX 501976104 $25.7M 1.53% 2,885,000 SH
15 ANNEXON INC ANNX 03589W102 $25.3M 1.51% 4,437,731 SH
16 RAPID MICRO BIOSYSTEMS INC RPID 75340L104 $14.6M 0.87% 8,434,560 SH
17 DISC MEDICINE INC IRON 254604101 $10.3M 0.61% 141,234 SH
18 ATEA PHARMACEUTICALS INC AVIR 04683R106 $9.7M 0.57% 2,075,639 SH
19 XILIO THERAPEUTICS INC XLO 98422T209 $6.4M 0.38% 664,021 SH
20 UPSTREAM BIO INC UPB 91678A107 $4.2M 0.25% 600,949 SH
21 NEWAMSTERDAM PHARMA COMPANY NAMSW N62509117 $2.1M 0.13% 99,999 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-14 $1.68B 21 0001193125-26-350470
2026-03-31 2026-05-15 $1.11B 20 0001193125-26-226961
2025-12-31 2026-02-17 $1.31B 19 0001193125-26-054833
2025-09-30 2025-11-14 $1.51B 21 0001193125-25-283094