Bain Capital Life Sciences Investors, LLC — 13F Holdings & Portfolio

CIK 1703031 · latest 13F-HR filed 2026-05-15

Bain Capital Life Sciences Investors, LLC manages $1.11B in 13F-reported U.S. long-equity assets across 20 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are HTFL (22.93%), NAMS (21.09%), OLMA (10.05%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 4 new positions, exited 3, added to 5, and trimmed 8.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

Loading holdings…
AUM

$1.11B

Long-equity book

Holdings

20

Distinct positions

Period

2026-03-31

Filed 2026-05-15

Q/Q Activity

+4 / −3 / ↑5 / ↓8

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • SOLID BIOSCIENCES INC$26.0M +58.3%
  • C4 THERAPEUTICS INC$5.2M +37.7%
  • CABALETTA BIO INC$4.8M +22.8%
  • ATEA PHARMACEUTICALS INC$3.8M +43.1%
  • ANNEXON INC$2.5M +9.6%
Show all 5

Top Trims

  • HEARTFLOW INC-$108.7M -29.9%
  • OLEMA PHARMACEUTICALS INC-$101.3M -47.6%
  • UPSTREAM BIO INC-$28.3M -78.4%
  • NEWAMSTERDAM PHARMA COMPANY-$22.4M -8.8%
  • SAVARA INC-$10.0M -9.5%
Show all 8

New Positions

  • CENTESSA PHARMACEUTICALS$25.2M
  • ALKERMES PLC$21.6M
  • DISC MEDICINE INC$9.0M
  • XILIO THERAPEUTICS INC$5.6M
Show all 4

Exited Positions

  • MERSANA THERAPEUTICS INC$10.0M
  • TANGO THERAPEUTICS INC$5.8M
  • XILIO THERAPEUTICS INC$4.7M
Show all 3
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 HEARTFLOW INC HTFL 42238D107 $254.2M 22.93% 10,448,158 SH
2 NEWAMSTERDAM PHARMA COMPANY NAMS N62509109 $233.9M 21.09% 7,306,566 SH
3 OLEMA PHARMACEUTICALS INC OLMA 68062P106 $111.4M 10.05% 7,473,238 SH
4 SAVARA INC SVRA 805111101 $96.1M 8.67% 17,600,621 SH
5 PHARVARIS N V PHVS N69605108 $75.6M 6.82% 2,675,509 SH
6 SOLID BIOSCIENCES INC SLDB 83422E204 $70.6M 6.37% 9,808,819 SH
7 X4 PHARMACEUTICALS INC XFOR 98420X202 $32.9M 2.97% 7,967,454 SH
8 DIANTHUS THERAPEUTICS INC DNTH 252828108 $30.4M 2.74% 362,470 SH
9 ANNEXON INC ANNX 03589W102 $28.9M 2.60% 5,212,674 SH
10 KYVERNA THERAPEUTICS INC KYTX 501976104 $26.8M 2.42% 3,110,000 SH
11 CABALETTA BIO INC CABA 12674W109 $26.0M 2.35% 9,677,125 SH
12 CENTESSA PHARMACEUTICALS CNTA 152309100 $25.2M 2.27% 635,000 SH
13 ALKERMES PLC ALKS G01767105 $21.6M 1.95% 610,000 SH
14 RAPID MICRO BIOSYSTEMS INC RPID 75340L104 $19.1M 1.73% 8,434,560 SH
15 C4 THERAPEUTICS INC CCCC 12529R107 $18.9M 1.70% 7,171,910 SH
16 ATEA PHARMACEUTICALS INC AVIR 04683R106 $12.7M 1.15% 2,360,638 SH
17 DISC MEDICINE INC IRON 254604101 $9.0M 0.81% 141,234 SH
18 UPSTREAM BIO INC UPB 91678A107 $7.8M 0.70% 867,211 SH
19 XILIO THERAPEUTICS INC XLO 98422T209 $5.6M 0.50% 664,021 SH
20 NEWAMSTERDAM PHARMA COMPANY NAMSW N62509117 $2.0M 0.18% 99,999 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-15 $1.11B 20 0001193125-26-226961
2025-12-31 2026-02-17 $1.31B 19 0001193125-26-054833
2025-09-30 2025-11-14 $1.51B 21 0001193125-25-283094