HOWARD HUGHES MEDICAL INSTITUTE — 13F Holdings & Portfolio
CIK 810386 · latest 13F-HR filed 2026-05-15
HOWARD HUGHES MEDICAL INSTITUTE manages $415.8M in 13F-reported U.S. long-equity assets across 31 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are SPY (13.79%), NVDA (13.51%), AAPL (12.13%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 3 new positions, exited 472, added to 27, and trimmed 1.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
$415.8M
Long-equity book
31
Distinct positions
2026-03-31
Filed 2026-05-15
+3 / −472 / ↑27 / ↓1
vs 2025-12-31
| Name | Title / Status | Ownership | Type |
|---|
Top Adds (vs prior quarter)
- NVIDIA CORPORATION$55.2M +5669.1%
- APPLE INC$49.6M +5727.4%
- ALPHABET INC$40.9M +10459.1%
- MICROSOFT CORP$37.1M +4794.5%
- AMAZON COM INC$27.2M +5628.2%
Exited Positions
- ALPHABET INC$313.8K
- BERKSHIRE HATHAWAY INC DEL$198.5K
- JPMORGAN CHASE & CO.$189.5K
- ELI LILLY & CO$183.8K
- VISA INC$127.7K
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | STATE STR SPDR S&P 500 ETF T | SPY | 78462F103 | $57.4M | 13.79% | 88,185 | SH |
| 2 | NVIDIA CORPORATION | NVDA | 67066G104 | $56.2M | 13.51% | 322,105 | SH |
| 3 | APPLE INC | AAPL | 037833100 | $50.4M | 12.13% | 198,755 | SH |
| 4 | ALPHABET INC | GOOGL | 02079K305 | $41.3M | 9.94% | 143,665 | SH |
| 5 | MICROSOFT CORP | MSFT | 594918104 | $37.9M | 9.11% | 102,314 | SH |
| 6 | AMAZON COM INC | AMZN | 023135106 | $27.7M | 6.66% | 132,871 | SH |
| 7 | TAIWAN SEMICONDUCTOR MANUFAC | TSM | 874039100 | $22.6M | 5.43% | 66,773 | SH |
| 8 | BROADCOM INC | AVGO | 11135F101 | $20.1M | 4.84% | 65,028 | SH |
| 9 | META PLATFORMS INC | META | 30303M102 | $17.6M | 4.24% | 30,787 | SH |
| 10 | TESLA INC | TSLA | 88160R101 | $15.3M | 3.68% | 41,177 | SH |
| 11 | ASML HLDG NV | ASML | N07059210 | $7.1M | 1.72% | 5,405 | SH |
| 12 | NETFLIX INC. | NFLX | 64110L106 | $5.6M | 1.36% | 58,670 | SH |
| 13 | MICRON TECHNOLOGY INC | MU | 595112103 | $5.3M | 1.28% | 15,704 | SH |
| 14 | ADVANCED MICRO DEVICES INC | AMD | 007903107 | $4.6M | 1.11% | 22,624 | SH |
| 15 | PALANTIR TECHNOLOGIES INC | PLTR | 69608A108 | $4.5M | 1.08% | 30,757 | SH |
| 16 | CISCO SYS INC | CSCO | 17275R102 | $3.9M | 0.94% | 50,326 | SH |
| 17 | APPLIED MATLS INC | AMAT | 038222105 | $3.8M | 0.90% | 10,984 | SH |
| 18 | LAM RESEARCH CORP | LRCX | 512807306 | $3.7M | 0.89% | 17,396 | SH |
| 19 | ORACLE CORP | ORCL | 68389X105 | $3.5M | 0.84% | 23,851 | SH |
| 20 | INTERNATIONAL BUSINESS MACHS | IBM | 459200101 | $3.2M | 0.76% | 13,023 | SH |
| 21 | KLA CORP | KLAC | 482480100 | $2.7M | 0.65% | 1,825 | SH |
| 22 | SAP SE | SAP | 803054204 | $2.5M | 0.61% | 14,868 | SH |
| 23 | INTEL CORP | INTC | 458140100 | $2.5M | 0.61% | 57,142 | SH |
| 24 | TEXAS INSTRS INC | TXN | 882508104 | $2.5M | 0.59% | 12,645 | SH |
| 25 | DISNEY WALT CO | DIS | 254687106 | $2.4M | 0.57% | 24,660 | SH |
| 26 | SALESFORCE INC | CRM | 79466L302 | $2.4M | 0.57% | 12,612 | SH |
| 27 | UBER TECHNOLOGIES INC | UBER | 90353T100 | $2.1M | 0.50% | 28,895 | SH |
| 28 | QUALCOMM INC | QCOM | 747525103 | $1.9M | 0.46% | 14,838 | SH |
| 29 | BOOKING HOLDINGS INC | BKNG | 09857L108 | $1.9M | 0.45% | 444 | SH |
| 30 | ACCENTURE PLC IRELAND | ACN | G1151C101 | $1.7M | 0.41% | 8,607 | SH |
| 31 | INTUIT | INTU | 461202103 | $1.6M | 0.39% | 3,794 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-03-31 | 2026-05-15 | $415.8M | 31 | 0001193125-26-225362 |
| 2025-12-31 | 2026-02-17 | $174.7M | 500 | 0001193125-26-052983 |
| 2025-09-30 | 2025-11-14 | $170.6M | 500 | 0001193125-25-281376 |