ORBIMED ADVISORS LLC
CIK 1055951 · last filed 2026-07-09
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
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Disclosed Exposure
$3.63B
Companies
74
Total Filings
229
Lifetime Open-Market Net
-$1.58B
Holdings By Company
Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| SION | Director | 2,469,959 | $46.55 | $114.98M | -$78.99M | 7 | 2026-07-09 |
| ELVN | 10%+ Owner | 220,882 | $53.76 | $11.87M | -$117.04M | 1 | 2026-06-24 |
| IMRA | Director | 7,388,902 | $14.49 | $107.07M | $11.99M | 4 | 2026-06-17 |
| PASG | 10%+ Owner | 385,918 | $4.57 | $1.76M | $5.69M | 4 | 2024-12-06 |
| MBX | Director | 653,787 | $60.06 | $39.27M | $36.00M | 1 | 2024-09-17 |
| scPharmaceuticals Inc. (SCPH) Delisted | 10%+ Owner | 252,858 | $5.67 | $1.43M | $42.00M | 2 | 2024-08-15 |
| KROS | Director | 119,522 | $10.07 | $1.20M | -$33.01M | 1 | 2024-08-15 |
| Terns Pharmaceuticals, Inc. (TERN) Delisted | Director | 755,635 | $52.95 | $40.01M | -$2.81M | 1 | 2024-07-17 |
| IRON | Director | 608,611 | $74.65 | $45.43M | -$76.34M | 3 | 2024-06-20 |
| NPCE | 10%+ Owner | 3,411,009 | $15.31 | $52.22M | -$17.22M | 5 | 2024-05-03 |
| ALPINE IMMUNE SCIENCES, INC. (ALPN) Delisted | Director | 2,416,181 | $64.97 | $156.98M | $11.40M | 3 | 2024-01-16 |
| ImageneBio, Inc. (IKNA) Delisted | Director | 13,107 | $17.16 | $224.9K | $40.65M | 3 | 2023-09-14 |
| Damora Therapeutics, Inc. (GLTO) Delisted | 10%+ Owner | 84,236 | $28.69 | $2.42M | -$3.71M | 2 | 2023-08-02 |
| Turnstone Biologics Corp. (TSBX) Delisted | Director | 2,682,599 | $0.35 | $952.3K | $10.00M | 1 | 2023-07-24 |
| Theseus Pharmaceuticals, Inc. (THRX) Delisted | Director | 17,063,000 | $4.06 | $69.28M | $4.39M | 1 | 2023-07-19 |
| TELA | 10%+ Owner | 2,891,542 | $0.67 | $1.94M | -$3.58M | 1 | 2023-04-21 |
| Verona Pharma plc (VRNA) Delisted | Director | 35,294,568 | $106.91 | $3.77B | -$272.00M | 1 | 2022-12-27 |
| Third Harmonic Bio, Inc. (THRD) Delisted | Director | 5,479,071 | $5.38 | $29.48M | $10.20M | 1 | 2022-09-21 |
| XTNT | Director | 215,415 | $0.43 | $91.7K | $6.81M | 5 | 2022-08-17 |
| EWTX | Director | 13,497,456 | $40.35 | $544.62M | $2.98M | 1 | 2022-05-20 |
| ARQT | 10%+ Owner | 3,937,764 | $28.42 | $111.91M | -$54.49M | 1 | 2022-04-08 |
| JANX | Director | 231,098 | $15.00 | $3.47M | -$2.46M | 1 | 2021-12-30 |
| Tricida, Inc. (TCDA) Delisted | Director | 27,584 | $0.11 | $3.0K | -$106.00M | 3 | 2021-11-17 |
| CMPX | Director | 3,571,428 | $2.04 | $7.29M | $56.25M | 1 | 2021-11-08 |
| CRVS | Director | 6,943,654 | $13.31 | $92.42M | $23.04M | 8 | 2021-09-22 |
| Repare Therapeutics Inc. (RPTX) Delisted | Director | 96,216 | $2.65 | $255.0K | -$2.69M | 2 | 2021-09-08 |
| SpringWorks Therapeutics, Inc. (SWTX) Delisted | 10%+ Owner | 6,185,936 | $46.99 | $290.68M | -$8.20M | 1 | 2021-06-09 |
| SYNLOGIC, INC. (SYBX) Delisted | Director | 246,444 | $0.69 | $170.0K | $0 | 1 | 2021-04-22 |
| ORIC | Director | 2,395,334 | $11.91 | $28.53M | -$20.06M | 2 | 2021-03-26 |
| Decibel Therapeutics, Inc. (DBTX) Delisted | Director | 218,568 | $4.91 | $1.07M | $120.00M | 1 | 2021-02-19 |
| ACET | Director | 56,430 | $8.20 | $462.7K | $0 | 1 | 2021-02-18 |
| CTI BIOPHARMA CORP (CTIC) Delisted | 10%+ Owner | 7,520,600 | $9.09 | $68.36M | -$14.00M | 1 | 2021-01-11 |
| Whitehawk Therapeutics, Inc. (ARPO) Delisted | Director | 1,427 | $33.00 | $47.1K | $5.90M | 2 | 2020-12-10 |
| PRLD | Director | 917,412 | $4.64 | $4.26M | $70.50M | 2 | 2020-09-30 |
| CalciMedica, Inc. (GRAY) Delisted | 10%+ Owner | 4,163,347 | $5.50 | $22.90M | $18.00M | 1 | 2020-09-29 |
| 89bio, Inc. (ETNB) Delisted | Director | 1,864,721 | $14.84 | $27.67M | -$30.80M | 1 | 2020-09-23 |
| INSP | Director | 2,175,264 | $51.97 | $113.05M | -$145.13M | 4 | 2020-08-19 |
| Fusion Pharmaceuticals Inc. (FUSN) Delisted | Director | 2,224,770 | $21.55 | $47.94M | $45.80M | 1 | 2020-07-02 |
| Prevail Therapeutics Inc. (PRVL) Delisted | Director | 13,822,463 | — | — | $30.00M | 1 | 2019-06-26 |
| NXTC | Director | 37,156 | $5.42 | $201.4K | $10.50M | 1 | 2019-05-13 |
| Turning Point Therapeutics, Inc. (TPTX) Delisted | Director | 1,120,730 | $76.01 | $85.19M | $12.96M | 1 | 2019-04-24 |
| Synthorx, Inc. (THOR) Delisted | Director | 1,363,636 | — | — | $30.00M | 1 | 2018-12-13 |
| SIBN | Director | 785,368 | $17.93 | $14.08M | $6.00M | 1 | 2018-10-19 |
| GH | 10%+ Owner | 1,525,492 | $143.62 | $219.09M | $0 | 1 | 2018-10-11 |
| ViewRay, Inc. (VRAY) Delisted | 10%+ Owner | 74,555 | $0.03 | $1.9K | -$59.33M | 7 | 2018-08-21 |
| ASND | Director | 4,901,310 | $254.44 | $1.25B | -$29.24M | 3 | 2018-06-06 |
| RYTM | 10%+ Owner | 2,769,659 | $108.04 | $299.23M | -$8.13M | 1 | 2018-05-21 |
| BOLD | Director | 3,616,700 | $2.47 | $8.93M | -$40.86M | 3 | 2018-03-12 |
| PALVELLA THERAPEUTICS, INC. (PIRS) Delisted | 10%+ Owner | 617 | $13.60 | $8.4K | -$141.8K | 1 | 2018-02-15 |
| KALA | 10%+ Owner | 1,346 | $0.66 | $889 | $18.52M | 2 | 2018-02-02 |
| ARMO BioSciences, Inc. (ARMO) Delisted | Director | 409,547 | — | — | $0 | 1 | 2018-01-30 |
| Loxo Oncology, Inc. (LOXO) Delisted | Director | 941,000 | — | — | -$98.10M | 2 | 2017-12-12 |
| Roka BioScience, Inc. (ROKA) Delisted | Director | 6,379 | — | — | -$719.9K | 3 | 2017-09-28 |
| GKOS | Director | 1,249,793 | $151.33 | $189.13M | -$114.29M | 3 | 2017-09-05 |
| Spyre Therapeutics, Inc. (AGLE) Delisted | 10%+ Owner | 1,469,524 | $12.01 | $17.65M | $1.69M | 1 | 2017-02-21 |
| Relypsa Inc (RLYP) Delisted | 10%+ Owner | 3,356,400 | — | — | -$388.16M | 1 | 2016-07-26 |
| Cartesian Therapeutics, Inc. (SELB) Delisted | Director | 12,193 | $0.88 | $10.7K | $23.10M | 1 | 2016-06-29 |
| OTONOMY, INC. (OTIC) Delisted | Director | 1,850,684 | $0.08 | $142.5K | $2.43M | 2 | 2015-11-30 |
| Dimension Therapeutics, Inc. (DMTX) Delisted | Director | 3,250,085 | — | — | $7.80M | 1 | 2015-10-29 |
| INTERCEPT PHARMACEUTICALS, INC. (ICPT) Delisted | Director | 1,271,901 | $19.00 | $24.17M | -$438.39M | 7 | 2015-03-30 |
| Mirati Therapeutics, Inc. (MRTX) Delisted | 10%+ Owner | 1,176,717 | $58.70 | $69.07M | -$413.2K | 2 | 2014-07-01 |
| ACCELERON PHARMA INC (XLRN) Delisted | 498,739 | $178.75 | $89.15M | $0 | 1 | 2013-09-26 | |
| AMBIT BIOSCIENCES CORP (AMBI) Delisted | 10%+ Owner | 1,464,322 | $0.54 | $790.1K | $700.5K | 1 | 2013-05-24 |
| SUPN | 10%+ Owner | 858,100 | $47.73 | $40.96M | -$6.84M | 1 | 2013-02-14 |
| AMRN | Director | 59,430 | $13.95 | $829.0K | -$35.03M | 4 | 2012-06-19 |
| PCRX | 10%+ Owner | 2,588,200 | $26.81 | $69.39M | -$7.77M | 2 | 2012-02-03 |
| Anthera Pharmaceuticals Inc (ANTH) Delisted | Director | 45,547 | — | — | -$8.54M | 5 | 2011-11-18 |
| ATHERSYS, INC / NEW (ATHX) Delisted | Director | 64,323 | $0.01 | $868 | -$1.16M | 4 | 2011-04-29 |
| NxStage Medical, Inc. (NXTM) Delisted | Director | 2,690,476 | — | — | -$14.97M | 9 | 2010-12-13 |
| GNOM | 10%+ Owner | 9,803 | $53.90 | $528.4K | $5.43M | 1 | 2010-11-16 |
| ARYx Therapeutics, Inc. (ARYX) Delisted | Director | 1,340,139 | — | — | -$10.00M | 3 | 2009-05-26 |
| ALBIREO PHARMA, INC. (BIOD) Delisted | Director | 60,430 | — | — | -$4.46M | 2 | 2008-02-14 |
| CRYOCOR INC (CRYO) Delisted | 10%+ Owner | 389,432 | — | — | $0 | 1 | 2007-06-19 |
| PODD | Director | 1,568,841 | $167.47 | $262.73M | $0 | 1 | 2007-05-18 |
Recent Filings · Page 4 of 23
229 filingsInsider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2025-03-10 | IRON | Notice (144) | −299,200 | -$16.66M | EDGAR |
| 2025-02-10 | SION | Mixed | +7,409,918 | $19.80M | EDGAR |
| 2025-01-06 | PASG | Notice (144) | −1,140,740 | -$945.7K | EDGAR |
| 2024-12-06 | PASG | Sell (S) | −194,206 | -$154.7K | EDGAR |
| 2024-12-04 | PASG | Notice (144) | −2,985,518 | -$2.66M | EDGAR |
| 2024-09-17 | MBX | Mixed | +11,436,645 | $36.00M | EDGAR |
| 2024-09-16 | PASG | Notice (144) | −927,572 | -$748.6K | EDGAR |
| 2024-08-15 | KROS | Sell (S) | −750,000 | -$33.01M | EDGAR |
| 2024-08-15 | scPharmaceuticals Inc. (SCPH) Delisted | Buy (P) | +1,500,000 | $6.00M | EDGAR |
| 2024-08-13 | KROS | Notice (144) | −29,400 | -$1.32M | EDGAR |
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.