ORBIMED ADVISORS LLC
CIK 1055951 · last filed 2026-05-11
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
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Disclosed Exposure
$3.11B
Companies
73
Total Filings
162
Lifetime Open-Market Net
-$1.41B
Holdings By Company
Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| SION | Director | 2,856,461 | $35.92 | $102.60M | -$60.73M | 5 | 2026-05-11 |
| PASG | 10%+ Owner | 7,718,369 | $5.81 | $44.84M | $5.69M | 4 | 2024-12-06 |
| MBX | Director | 653,787 | $35.51 | $23.22M | $36.00M | 1 | 2024-09-17 |
| scPharmaceuticals Inc. (SCPH) Delisted | 10%+ Owner | 252,858 | $5.67 | $1.43M | $42.00M | 2 | 2024-08-15 |
| KROS | Director | 119,522 | $10.15 | $1.21M | -$33.01M | 1 | 2024-08-15 |
| Terns Pharmaceuticals, Inc. (TERN) Delisted | Director | 755,635 | $52.95 | $40.01M | -$2.81M | 1 | 2024-07-17 |
| IRON | Director | 608,611 | $67.99 | $41.38M | -$76.34M | 3 | 2024-06-20 |
| NPCE | 10%+ Owner | 3,411,009 | $15.64 | $53.35M | -$17.22M | 5 | 2024-05-03 |
| ALPINE IMMUNE SCIENCES, INC. (ALPN) Delisted | Director | 2,416,181 | $64.97 | $156.98M | $11.40M | 3 | 2024-01-16 |
| ImageneBio, Inc. (IKNA) Delisted | Director | 157,288 | $17.16 | $2.70M | $40.65M | 3 | 2023-09-14 |
| Damora Therapeutics, Inc. (GLTO) Delisted | 10%+ Owner | 2,105,909 | $28.69 | $60.42M | -$3.71M | 2 | 2023-08-02 |
| Turnstone Biologics Corp. (TSBX) Delisted | Director | 2,682,599 | $0.35 | $952.3K | $10.00M | 1 | 2023-07-24 |
| Theseus Pharmaceuticals, Inc. (THRX) Delisted | Director | 17,063,000 | $4.06 | $69.28M | $4.39M | 1 | 2023-07-19 |
| IMRA | Director | 288,114 | $17.02 | $4.90M | $50.00M | 3 | 2023-05-19 |
| TELA | 10%+ Owner | 2,891,542 | $0.86 | $2.49M | -$3.58M | 1 | 2023-04-21 |
| Verona Pharma plc (VRNA) Delisted | Director | 35,294,568 | $106.91 | $3.77B | -$272.00M | 1 | 2022-12-27 |
| Third Harmonic Bio, Inc. (THRD) Delisted | Director | 5,479,071 | $5.38 | $29.48M | $10.20M | 1 | 2022-09-21 |
| XTNT | Director | 215,415 | $0.44 | $94.8K | $6.81M | 5 | 2022-08-17 |
| EWTX | Director | 13,497,456 | $34.83 | $470.12M | $2.98M | 1 | 2022-05-20 |
| ARQT | 10%+ Owner | 3,937,764 | $24.38 | $96.00M | -$54.49M | 1 | 2022-04-08 |
| JANX | Director | 231,098 | $13.56 | $3.13M | -$2.46M | 1 | 2021-12-30 |
| Tricida, Inc. (TCDA) Delisted | Director | 27,584 | $0.11 | $3.0K | -$106.00M | 3 | 2021-11-17 |
| CMPX | Director | 3,571,428 | $2.03 | $7.25M | $56.25M | 1 | 2021-11-08 |
| CRVS | Director | 6,943,654 | $11.93 | $82.84M | $23.04M | 8 | 2021-09-22 |
| Repare Therapeutics Inc. (RPTX) Delisted | Director | 96,216 | $2.65 | $255.0K | -$2.69M | 2 | 2021-09-08 |
| SpringWorks Therapeutics, Inc. (SWTX) Delisted | 10%+ Owner | 6,185,936 | $46.99 | $290.68M | -$8.20M | 1 | 2021-06-09 |
| SYBX | Director | 3,696,662 | $0.69 | $2.55M | $0 | 1 | 2021-04-22 |
| ORIC | Director | 2,395,334 | $8.27 | $19.81M | -$20.06M | 2 | 2021-03-26 |
| Decibel Therapeutics, Inc. (DBTX) Delisted | Director | 218,568 | $4.91 | $1.07M | $120.00M | 1 | 2021-02-19 |
| ACET | Director | 902,885 | $8.05 | $7.27M | $0 | 1 | 2021-02-18 |
| CTI BIOPHARMA CORP (CTIC) Delisted | 10%+ Owner | 7,520,600 | $9.09 | $68.36M | -$14.00M | 1 | 2021-01-11 |
| Whitehawk Therapeutics, Inc. (ARPO) Delisted | Director | 21,400 | $33.00 | $706.2K | $5.90M | 2 | 2020-12-10 |
| PRLD | Director | 917,412 | $4.49 | $4.12M | $70.50M | 2 | 2020-09-30 |
| CalciMedica, Inc. (GRAY) Delisted | 10%+ Owner | 4,163,347 | $5.50 | $22.90M | $18.00M | 1 | 2020-09-29 |
| 89bio, Inc. (ETNB) Delisted | Director | 1,864,721 | $14.84 | $27.67M | -$30.80M | 1 | 2020-09-23 |
| INSP | Director | 2,175,264 | $42.70 | $92.88M | -$145.13M | 4 | 2020-08-19 |
| Fusion Pharmaceuticals Inc. (FUSN) Delisted | Director | 2,224,770 | $21.55 | $47.94M | $45.80M | 1 | 2020-07-02 |
| Prevail Therapeutics Inc. (PRVL) Delisted | Director | 13,822,463 | — | — | $30.00M | 1 | 2019-06-26 |
| NXTC | Director | 445,866 | $2.08 | $925.2K | $10.50M | 1 | 2019-05-13 |
| Turning Point Therapeutics, Inc. (TPTX) Delisted | Director | 1,120,730 | $76.01 | $85.19M | $12.96M | 1 | 2019-04-24 |
| Synthorx, Inc. (THOR) Delisted | Director | 1,363,636 | — | — | $30.00M | 1 | 2018-12-13 |
| SIBN | Director | 785,368 | $15.42 | $12.11M | $6.00M | 1 | 2018-10-19 |
| GH | 10%+ Owner | 1,525,492 | $131.62 | $200.79M | $0 | 1 | 2018-10-11 |
| ViewRay, Inc. (VRAY) Delisted | 10%+ Owner | 74,555 | $0.03 | $1.9K | -$59.33M | 7 | 2018-08-21 |
| ASND | Director | 4,901,310 | $218.06 | $1.07B | -$29.24M | 3 | 2018-06-06 |
| RYTM | 10%+ Owner | 2,769,659 | $88.38 | $244.78M | -$8.13M | 1 | 2018-05-21 |
| BOLD | Director | 3,616,700 | $1.41 | $5.10M | -$40.86M | 3 | 2018-03-12 |
| PALVELLA THERAPEUTICS, INC. (PIRS) Delisted | 10%+ Owner | 49,328 | $13.60 | $670.9K | -$141.8K | 1 | 2018-02-15 |
| KALA | 10%+ Owner | 3,362,160 | $2.63 | $8.84M | $18.52M | 2 | 2018-02-02 |
| ARMO BioSciences, Inc. (ARMO) Delisted | Director | 409,547 | — | — | $0 | 1 | 2018-01-30 |
| Loxo Oncology, Inc. (LOXO) Delisted | Director | 941,000 | — | — | -$98.10M | 2 | 2017-12-12 |
| Roka BioScience, Inc. (ROKA) Delisted | Director | 6,379 | — | — | -$719.9K | 3 | 2017-09-28 |
| GKOS | Director | 1,249,793 | $126.81 | $158.49M | -$114.29M | 3 | 2017-09-05 |
| Spyre Therapeutics, Inc. (AGLE) Delisted | 10%+ Owner | 1,469,524 | $12.01 | $17.65M | $1.69M | 1 | 2017-02-21 |
| Relypsa Inc (RLYP) Delisted | 10%+ Owner | 3,356,400 | — | — | -$388.16M | 1 | 2016-07-26 |
| Cartesian Therapeutics, Inc. (SELB) Delisted | Director | 12,193 | $0.88 | $10.7K | $23.10M | 1 | 2016-06-29 |
| OTONOMY, INC. (OTIC) Delisted | Director | 1,850,684 | $0.08 | $142.5K | $2.43M | 2 | 2015-11-30 |
| Dimension Therapeutics, Inc. (DMTX) Delisted | Director | 3,250,085 | — | — | $7.80M | 1 | 2015-10-29 |
| INTERCEPT PHARMACEUTICALS, INC. (ICPT) Delisted | Director | 1,271,901 | $19.00 | $24.17M | -$438.39M | 7 | 2015-03-30 |
| Mirati Therapeutics, Inc. (MRTX) Delisted | 10%+ Owner | 1,176,717 | $58.70 | $69.07M | -$413.2K | 2 | 2014-07-01 |
| ACCELERON PHARMA INC (XLRN) Delisted | 498,739 | $178.75 | $89.15M | $0 | 1 | 2013-09-26 | |
| AMBIT BIOSCIENCES CORP (AMBI) Delisted | 10%+ Owner | 1,464,322 | $0.54 | $790.1K | $700.5K | 1 | 2013-05-24 |
| SUPN | 10%+ Owner | 858,100 | $44.41 | $38.11M | -$6.84M | 1 | 2013-02-14 |
| AMRN | Director | 1,188,600 | $15.24 | $18.11M | -$35.03M | 4 | 2012-06-19 |
| PCRX | 10%+ Owner | 2,588,200 | $22.99 | $59.50M | -$7.77M | 2 | 2012-02-03 |
| Anthera Pharmaceuticals Inc (ANTH) Delisted | Director | 2,915,000 | — | — | -$8.54M | 5 | 2011-11-18 |
| ATHERSYS, INC / NEW (ATHX) Delisted | Director | 1,608,075 | $0.01 | $21.7K | -$1.16M | 4 | 2011-04-29 |
| NxStage Medical, Inc. (NXTM) Delisted | Director | 2,690,476 | — | — | -$14.97M | 9 | 2010-12-13 |
| GNOM | 10%+ Owner | 39,211 | $48.95 | $1.92M | $5.43M | 1 | 2010-11-16 |
| ARYx Therapeutics, Inc. (ARYX) Delisted | Director | 1,340,139 | — | — | -$10.00M | 3 | 2009-05-26 |
| ALBIREO PHARMA, INC. (BIOD) Delisted | Director | 1,812,892 | — | — | -$4.46M | 2 | 2008-02-14 |
| CRYOCOR INC (CRYO) Delisted | 10%+ Owner | 389,432 | — | — | $0 | 1 | 2007-06-19 |
| PODD | Director | 1,568,841 | $149.70 | $234.86M | $0 | 1 | 2007-05-18 |
Recent Filings · Page 5 of 17
162 filingsForm 4 transactions across all companies, newest first.
| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2021-08-25 | Repare Therapeutics Inc. (RPTX) Delisted | Sell (S) | −54,645 | -$1.87M | EDGAR |
| 2021-07-23 | IMRA | Buy (P) | +3,333,332 | $20.00M | EDGAR |
| 2021-06-09 | SpringWorks Therapeutics, Inc. (SWTX) Delisted | Sell (S) | −96,106 | -$8.20M | EDGAR |
| 2021-04-22 | SYBX | Grant (A) | +3,333,332 | $10.00M | EDGAR |
| 2021-04-13 | ImageneBio, Inc. (IKNA) Delisted | Mixed | +22,569,591 | $20.32M | EDGAR |
| 2021-04-01 | ImageneBio, Inc. (IKNA) Delisted | Mixed | +22,569,591 | $20.32M | EDGAR |
| 2021-03-26 | ORIC | Sell (S) | −224,596 | -$5.51M | EDGAR |
| 2021-03-15 | ORIC | Sell (S) | −476,564 | -$14.55M | EDGAR |
| 2021-02-19 | Decibel Therapeutics, Inc. (DBTX) Delisted | Mixed | +19,780,768 | $120.00M | EDGAR |
| 2021-02-19 | CRVS | Buy (P) | +2,571,428 | $9.00M | EDGAR |
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.