DFTX · Insider Trading

Definium Therapeutics, Inc. Common Shares

Every open-market purchase and sale reported by DFTX officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
43
most recent
Open-Market Buys
0
code P
Sales
13
code S
Reporting Insiders
11
current holders
DFTX — Recent Form 4 Transactions (latest 2026-09-29)
FiledInsiderRole TypeSharesValue
2026-09-29 Brandi Roberts Chief Financial Officer Sell −3,377 −$123.50K
2026-09-29 Robert Barrow Chief Executive Officer Sell −31,550 −$1.15M
2026-09-29 Daniel Karlin Chief Medical Officer Sell −10,853 −$396.89K
2026-09-29 Mark Sullivan Chief Legal Officer Sell −14,051 −$513.85K
2026-09-29 Matthew T. Wiley Chief Commercial Officer Sell −3,097 −$113.26K
2026-09-18 Andreas Krebs Director M +1,629 +$57.86K
2026-09-18 Carol A Vallone Director M +1,086 +$38.57K
2026-09-14 Matthew T. Wiley Chief Commercial Officer A +125,000 —
2026-09-14 Brandi Roberts Chief Financial Officer A +125,000 —
2026-09-14 Mark Sullivan Chief Legal Officer A +125,000 —
2026-09-14 Robert Barrow Chief Executive Officer A +750,000 —
2026-09-14 Daniel Karlin Chief Medical Officer A +200,000 —
2026-09-04 Robert Barrow Chief Executive Officer MIXED +20,977 −$721.73K
2026-08-12 Matthew T. Wiley Chief Commercial Officer A +62,500 —
2026-08-12 Brandi Roberts Chief Financial Officer A +62,500 —
2026-08-12 Mark Sullivan Chief Legal Officer A +62,500 —
2026-08-12 Robert Barrow Chief Executive Officer A +375,000 —
2026-08-12 Daniel Karlin Chief Medical Officer A +100,000 —
2026-06-26 Daniel Karlin Chief Medical Officer Sell −10,035 −$451.88K
2026-06-26 Mark Sullivan Chief Legal Officer Sell −13,008 −$585.75K
2026-06-26 Matthew T. Wiley Chief Commercial Officer Sell −2,867 −$129.10K
2026-06-26 Robert Barrow Chief Executive Officer Sell −29,208 −$1.32M
2026-06-26 Brandi Roberts Chief Financial Officer Sell −3,013 −$135.68K
2026-06-22 Daniel Karlin Chief Medical Officer A +100,000 —
2026-06-22 Mark Sullivan Chief Legal Officer A +62,500 —
2026-06-22 Matthew T. Wiley Chief Commercial Officer A +62,500 —
2026-06-22 Brandi Roberts Chief Financial Officer A +62,500 —
2026-06-22 Robert Barrow Chief Executive Officer A +375,000 —
2026-06-15 Andreas Krebs Director A +4,666 —
2026-06-15 Roger Crystal Director A +4,666 —
2026-06-15 Carol A Vallone Director A +4,666 —
2026-06-15 Roger Adsett Director A +3,555 —
2026-06-15 Suzanne Louise Bruhn Director A +4,666 —
2026-06-15 David W Gryska Director A +4,666 —
2026-03-26 Daniel Karlin Chief Medical Officer Sell −8,018 −$148.09K
2026-03-26 Robert Barrow Chief Executive Officer Sell −24,431 −$451.24K
2026-03-26 Mark Sullivan Chief Legal Officer Sell −10,702 −$197.67K
2026-02-05 Brandi Roberts Chief Financial Officer A +150,000 —
2026-02-05 Robert Barrow Chief Executive Officer A +320,000 —
2026-02-05 Mark Sullivan Chief Legal Officer A +125,000 —
2026-02-05 Daniel Karlin Chief Medical Officer A +150,000 —
2026-02-05 Matthew T. Wiley Chief Commercial Officer A +115,000 —
2026-01-29 Roger Adsett Director A +50,000 deriv. —
DFTX — Current Insider Holders
InsiderRole Shares HeldValue
Robert Barrow Chief Executive Officer 2,213,090 $72.97M
Daniel Karlin Chief Medical Officer 792,846 $26.14M
Mark Sullivan Chief Legal Officer 494,228 $16.29M
Brandi Roberts Chief Financial Officer 394,528 $13.01M
Matthew T. Wiley Chief Commercial Officer 359,036 $11.84M
Suzanne Louise Bruhn Director 24,289 $800.81K
Roger Crystal Director 24,289 $800.81K
Carol A Vallone Director 22,296 $735.10K
Andreas Krebs Director 21,402 $705.62K
David W Gryska Director 19,900 $656.10K
Roger Adsett Director 3,555 $117.21K
DFTX Insider Trading FAQ
Who are the insiders at DFTX?
11 officers, directors and 10%+ beneficial owners currently report holdings in DFTX via SEC Form 4.
Are DFTX insiders buying or selling?
Across the 43 most recent Form 4 filings for DFTX, 0 were open-market purchases (code P) and 13 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is DFTX insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent DFTX filing is dated 2026-09-29.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the DFTX quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.