OPK (Opko Health Inc.)
Insider Trading Activity
Every open-market purchase and sale reported by OPK officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
| Filed | Insider | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-28 | Steven D Rubin | Executive VP-Administration | F | — | — |
| 2026-07-28 | Adam Logal | Sr. Vice President, CFO | F | — | — |
| 2026-06-22 | JOHN A PAGANELLI | Director | A | — | — |
| 2026-06-22 | ROGER MD MEDEL | Director | A | — | — |
| 2026-06-22 | Alice Lin-Tsing Yu | Director | A | — | — |
| 2026-06-22 | SUBBARAO V UPPALURI | Director | A | — | — |
| 2026-06-22 | Prem A Lachman | Director | A | — | — |
| 2026-06-22 | RICHARD C JR PFENNIGER | Director | A | — | — |
| 2026-03-20 | SUBBARAO V UPPALURI | Director | A | — | — |
| 2026-03-20 | JOHN A PAGANELLI | Director | Buy | — | — |
| 2025-11-21 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-11-20 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-11-19 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-11-18 | PHILLIP MD ET AL FROST | CEO & Chairman | MIXED | — | — |
| 2025-10-31 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2025-08-19 | Frost Gamma Investments Trust | 10%+ Owner | G | — | — |
| 2025-08-08 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-05-29 | Adam Logal | Sr. Vice President, CFO | A | — | — |
| 2025-05-29 | PHILLIP MD ET AL FROST | CEO & Chairman | A | — | — |
| 2025-05-29 | JANE PH D HSIAO | Vice Chairman & CTO | A | — | — |
| 2025-05-29 | Gary J. Nabel | Chief Innovation Officer | A | — | — |
| 2025-05-29 | Elias A. Zerhouni | Vice Chairman and President | A | — | — |
| 2025-05-29 | Steven D Rubin | Executive VP-Administration | A | — | — |
| 2025-04-23 | ROGER MD MEDEL | Director | A | — | — |
| 2025-04-23 | RICHARD M KRASNO | Director | A | — | — |
| 2025-04-23 | Alice Lin-Tsing Yu | Director | A | — | — |
| 2025-04-23 | JOHN A PAGANELLI | Director | A | — | — |
| 2025-04-23 | RICHARD C JR PFENNIGER | Director | A | — | — |
| 2025-04-23 | Prem A Lachman | Director | A | — | — |
| 2025-04-10 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-04-08 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-04-01 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2025-03-28 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-03-17 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-03-04 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-03-03 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2025-02-28 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-01-28 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2025-01-17 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2025-01-15 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2024-12-13 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2024-12-11 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2024-11-29 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2024-11-22 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2024-11-20 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2024-11-14 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2024-11-08 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2024-09-27 | Frost Gamma Investments Trust | 10%+ Owner | Buy | — | — |
| 2024-09-27 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| 2024-09-26 | PHILLIP MD ET AL FROST | CEO & Chairman | Buy | — | — |
| Insider | Role | Shares Held | Value |
|---|---|---|---|
| — | 10%+ Owner | 220,275,399 | — |
| — | CEO & Chairman | 33,696,128 | — |
| — | Vice Chairman & CTO | 33,627,284 | — |
| — | 10%+ Owner | 33,026,128 | — |
| — | Executive VP-Administration | 26,663,028 | — |
| — | Vice Chairman and President | 20,367,114 | — |
| — | Director | 4,160,728 | — |
| — | Sr Vice President - CFO | 3,984,869 | — |
| — | Chief Innovation Officer | 1,052,021 | — |
| — | Director | 898,825 | — |
| — | Sr. Vice President, CFO | 563,396 | — |
| — | Director | 403,515 | — |
| — | Director | 325,000 | — |
| — | Director | 324,088 | — |
| — | Director | 312,612 | — |
| — | Director | 190,227 | — |
| — | SVP OPKO; Exec Chairman BRLI | 125,000 | — |
| — | Director | 103,333 | — |
| — | Director | 100,000 | — |
| — | Director | 65,000 | — |
| — | See Remarks | 2,200 | — |
| — | Director | 1,000 | — |
Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.
Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.
Full filing history and per-insider positions are on the OPK quote page; the site-wide leaderboard is on the insider transactions hub.