VRTX · Insider Trading

Vertex Pharmaceuticals Inc

Every open-market purchase and sale reported by VRTX officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
0
code P
Sales
21
code S
Reporting Insiders
24
current holders
VRTX — Recent Form 4 Transactions (latest 2026-09-10)
FiledInsiderRole TypeSharesValue
2026-09-10 Jasper van Grunsven EVP, CP and NPPO A +8,682 —
2026-09-01 Kristen Ambrose SVP & Chief Accounting Officer A +5,000 —
2026-08-31 Bruce I Sachs Director G −6,000 —
2026-07-23 Amit Sachdev EVP Chief Patient & Ext Af Off A +8,251 —
2026-07-23 Ourania Tatsis EVP, Chief Reg. & Quality Off. A +8,251 —
2026-07-17 Alan M Garber Director A +31 deriv. —
2026-07-17 Bruce I Sachs Director A +99 deriv. —
2026-07-07 Duncan McKechnie EVP, Chief Commercial Officer Sell −1,541 −$799.78K
2026-07-07 Ourania Tatsis EVP, Chief Reg. & Quality Off. Sell −1,500 −$787.49K
2026-07-06 Joy Liu EVP and Chief Legal Officer Sell −828 −$416.24K
2026-06-23 Carmen Bozic EVP and CMO Sell −1,020 −$471.41K
2026-06-17 Carmen Bozic EVP and CMO Sell −4,062 −$1.83M
2026-06-09 Carmen Bozic EVP and CMO Sell −1,745 −$785.25K
2026-06-03 Joy Liu EVP and Chief Legal Officer Sell −828 −$364.25K
2026-06-02 Carmen Bozic EVP and CMO Sell −1,974 −$888.30K
2026-05-19 Carmen Bozic EVP and CMO Sell −1,354 −$613.97K
2026-05-19 Mark E. Bunnage EVP, Chief Scientific Officer Sell −33 −$14.96K
2026-05-14 Carmen Bozic EVP and CMO Sell −6,988 −$3.14M
2026-05-05 Sangeeta N. Bhatia Director MIXED +625 −$134.75K
2026-05-05 Lloyd Carney Director A +2,866 deriv. —
2026-05-05 Alan M Garber Director A +472 —
2026-05-05 Michel Lagarde Director A +2,866 deriv. —
2026-05-05 Joy Liu EVP and Chief Legal Officer Sell −1,104 −$469.22K
2026-05-05 Diana McKenzie Director MIXED +147 —
2026-05-05 Bruce I Sachs Director A +2,866 deriv. —
2026-05-05 Jennifer Schneider Director MIXED −324 —
2026-05-05 Nancy Thornberry Director MIXED +74 —
2026-05-05 Suketu Upadhyay Director D −796 —
2026-04-17 Alan M Garber Director A +33 deriv. —
2026-04-17 Bruce I Sachs Director A +107 deriv. —
2026-04-17 Suketu Upadhyay Director A +80 deriv. —
2026-04-03 Joy Liu EVP and Chief Legal Officer Sell −978 −$439.29K
2026-03-31 Carmen Bozic EVP and CMO Sell −2,329 −$1.05M
2026-03-17 Carmen Bozic EVP and CMO Sell −2,329 −$1.12M
2026-03-13 Duncan McKechnie EVP, Chief Commercial Officer Sell −2,633 −$1.31M
2026-03-06 Duncan McKechnie EVP, Chief Commercial Officer Sell −2,437 −$1.16M
2026-03-04 Joy Liu EVP and Chief Legal Officer Sell −892 −$442.40K
2026-03-03 Carmen Bozic EVP and CMO Sell −2,329 −$1.12M
2026-03-03 Reshma Kewalramani CEO & President Sell −40,000 −$19.74M
2026-03-02 Kristen Ambrose SVP & Chief Accounting Officer Sell −357 −$172.56K
2026-02-26 Kristen Ambrose SVP & Chief Accounting Officer MIXED −769 −$373.33K
2026-02-26 Edward Morrow Atkinson III EVP, Chief Technical Ops. Off. MIXED −2,295 −$1.11M
2026-02-26 Jonathan Biller EVP and Chief Legal Officer MIXED −2,089 −$1.01M
2026-02-26 Carmen Bozic EVP and CMO F −1,453 −$704.86K
2026-02-26 Mark E. Bunnage EVP, Chief Scientific Officer MIXED −1,202 −$583.87K
2026-02-26 Reshma Kewalramani CEO & President F −4,981 −$2.42M
2026-02-26 Jeffrey M Leiden Executive Chairman F −3,547 −$1.72M
2026-02-26 Duncan McKechnie EVP, Chief Commercial Officer MIXED −5,783 −$2.82M
2026-02-26 Amit Sachdev EVP Chief Patient & Ext Af Off MIXED −3,364 −$1.63M
2026-02-26 Ourania Tatsis EVP, Chief Reg. & Quality Off. MIXED −1,887 −$915.72K
VRTX — Current Insider Holders
InsiderRole Shares HeldValue
Reshma Kewalramani CEO & President 127,596 $65.08M
Amit Sachdev EVP Chief Patient & Ext Af Off 73,149 $37.31M
Stuart A Arbuckle EVP, COO 63,508 $32.39M
Ourania Tatsis EVP, Chief Reg. & Quality Off. 53,572 $27.33M
Charles F Wagner Jr EVP, CO & FO 47,042 $24.00M
Bruce I Sachs Director 39,000 $19.89M
Jeffrey M Leiden Executive Chairman 35,237 $17.97M
David Altshuler EVP, Chief Scientific Officer 31,149 $15.89M
Joy Liu EVP and Chief Legal Officer 19,131 $9.76M
Edward Morrow Atkinson III EVP, Chief Technical Ops. Off. 19,100 $9.74M
Carmen Bozic EVP and CMO 15,933 $8.13M
Jonathan Biller EVP and Chief Legal Officer 14,604 $7.45M
Kristen Ambrose SVP & Chief Accounting Officer 11,624 $5.93M
Duncan McKechnie EVP, Chief Commercial Officer 11,001 $5.61M
Jasper van Grunsven EVP, CP and NPPO 8,682 $4.43M
Alan M Garber Director 7,344 $3.75M
Mark E. Bunnage EVP, Chief Scientific Officer 7,284 $3.72M
Lloyd Carney Director 6,315 $3.22M
Sangeeta N. Bhatia Director 4,924 $2.51M
Diana McKenzie Director 3,381 $1.72M
Jennifer Schneider Director 2,190 $1.12M
Nancy Thornberry Director 2,109 $1.08M
Suketu Upadhyay Director 1,558 $794.70K
Michel Lagarde Director 1,132 $577.41K
VRTX Insider Trading FAQ
Who are the insiders at VRTX?
24 officers, directors and 10%+ beneficial owners currently report holdings in VRTX via SEC Form 4.
Are VRTX insiders buying or selling?
Across the 50 most recent Form 4 filings for VRTX, 0 were open-market purchases (code P) and 21 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is VRTX insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent VRTX filing is dated 2026-09-10.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the VRTX quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.