VYNE · Insider Trading

VYNE Therapeutics Inc. Common Stock

Every open-market purchase and sale reported by VYNE officers, directors and 10%+ beneficial owners on SEC Form 4, which must be filed within two business days of the transaction. Sales often reflect scheduled 10b5-1 plans or tax withholding rather than a directional view, so read counts alongside the size and the filer.

Form 4 Filings
50
most recent
Open-Market Buys
1
code P
Sales
0
code S
Reporting Insiders
5
current holders
VYNE — Recent Form 4 Transactions (latest 2026-07-24)
FiledInsiderRole TypeSharesValue
2026-07-24 Iain Stuart CHIEF SCIENTIFIC OFFICER F −15,405 −$13.83K
2026-07-24 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −22,516 −$20.21K
2026-07-24 Tyler Zeronda CHIEF FINANCIAL OFFICER F −22,516 −$20.21K
2026-07-24 David Domzalski PRESIDENT AND CEO F −79,391 −$71.26K
2026-07-02 Iain Stuart CHIEF SCIENTIFIC OFFICER F −2,370 −$1.54K
2026-07-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −3,464 −$2.25K
2026-07-02 David Domzalski PRESIDENT AND CEO F −12,214 −$7.95K
2026-07-02 Tyler Zeronda CHIEF FINANCIAL OFFICER F −3,464 −$2.25K
2026-06-02 David Domzalski PRESIDENT AND CEO A +30,791 +$9.55K
2026-04-02 Tyler Zeronda CHIEF FINANCIAL OFFICER F −4,007 −$2.39K
2026-04-02 David Domzalski PRESIDENT AND CEO F −14,232 −$8.50K
2026-04-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −4,007 −$2.39K
2026-04-02 Iain Stuart CHIEF SCIENTIFIC OFFICER F −2,876 −$1.72K
2026-01-05 Iain Stuart CHIEF SCIENTIFIC OFFICER F −2,448 −$1.42K
2026-01-05 David Domzalski PRESIDENT AND CEO F −12,684 −$7.36K
2026-01-05 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −3,579 −$2.08K
2026-01-05 Tyler Zeronda CHIEF FINANCIAL OFFICER F −7,858 −$4.56K
2025-12-15 Elisabeth Sandoval Little Director A +20,000 deriv. —
2025-12-15 Sharon Barbari Director A +20,000 deriv. —
2025-12-15 Steven L Basta Director A +20,000 deriv. —
2025-12-15 Patrick G Lepore Director A +20,000 deriv. —
2025-10-02 Iain Stuart CHIEF SCIENTIFIC OFFICER F −2,453 −$822
2025-10-02 David Domzalski PRESIDENT AND CEO F −12,676 −$4.25K
2025-10-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −3,581 −$1.20K
2025-10-02 Tyler Zeronda CHIEF FINANCIAL OFFICER F −3,420 −$1.15K
2025-07-02 Iain Stuart CHIEF SCIENTIFIC OFFICER F −2,453 −$4.05K
2025-07-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −3,581 −$5.91K
2025-07-02 David Domzalski PRESIDENT AND CEO F −12,676 −$20.92K
2025-07-02 Tyler Zeronda CHIEF FINANCIAL OFFICER F −3,420 −$5.64K
2025-06-03 David Domzalski PRESIDENT AND CEO A +8,681 +$7.03K
2025-06-03 Mutya Harsch CHIEF LEGAL OFFICER AND GC A +1,145 +$927
2025-04-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −8,828 −$13.95K
2025-04-02 David Domzalski PRESIDENT AND CEO F −30,498 −$48.19K
2025-04-02 Iain Stuart CHIEF SCIENTIFIC OFFICER F −6,044 −$9.55K
2025-04-02 Tyler Zeronda CHIEF FINANCIAL OFFICER F −8,399 −$13.27K
2025-01-23 David Domzalski PRESIDENT AND CEO A +730,000 deriv. —
2025-01-23 Tyler Zeronda CHIEF FINANCIAL OFFICER A +230,000 deriv. —
2025-01-23 Iain Stuart CHIEF SCIENTIFIC OFFICER A +230,000 deriv. —
2025-01-23 Mutya Harsch CHIEF LEGAL OFFICER AND GC A +230,000 deriv. —
2025-01-16 Patrick G Lepore Director Buy +15,000 +$43.80K
2025-01-02 David Domzalski PRESIDENT AND CEO F −24,536 −$82.20K
2025-01-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC F −4,697 −$15.73K
2025-01-02 Tyler Zeronda CHIEF FINANCIAL OFFICER F −4,675 −$15.66K
2025-01-02 Iain Stuart CHIEF SCIENTIFIC OFFICER F −4,857 −$16.27K
2024-12-13 Christine Borowski Director A +20,000 deriv. —
2024-12-13 Sharon Barbari Director A +20,000 deriv. —
2024-12-13 Anthony D Bruno Director A +20,000 deriv. —
2024-12-13 Elisabeth Sandoval Director A +20,000 deriv. —
2024-12-13 Patrick G Lepore Director A +20,000 deriv. —
2024-12-13 Steven L Basta Director A +20,000 deriv. —
VYNE — Current Insider Holders
InsiderRole Shares HeldValue
David Domzalski PRESIDENT AND CEO 6,943 $198.29K
Iain Stuart CHIEF SCIENTIFIC OFFICER 1,919 $54.81K
Mutya Harsch CHIEF LEGAL OFFICER AND GC 1,918 $54.78K
Tyler Zeronda CHIEF FINANCIAL OFFICER 1,498 $42.78K
Patrick G Lepore Director 1,029 $29.39K
VYNE Insider Trading FAQ
Who are the insiders at VYNE?
5 officers, directors and 10%+ beneficial owners currently report holdings in VYNE via SEC Form 4.
Are VYNE insiders buying or selling?
Across the 50 most recent Form 4 filings for VYNE, 1 were open-market purchases (code P) and 0 were sales (code S). Sales frequently reflect scheduled 10b5-1 plans or tax withholding rather than a view on the stock.
How current is VYNE insider data?
Form 4 must be filed within two business days of the transaction, so this is close to real time. The most recent VYNE filing is dated 2026-07-24.
How to read Form 4 activity

Form 4 reports a change in beneficial ownership by an officer, director or 10%+ holder, and must be filed within two business days of the transaction — so this is close to real time, unlike the 45-day-lagged 13F institutional data.

Transaction codes matter more than the raw buy/sell count. Code P is an open-market purchase — an insider choosing to buy with their own money, which is the signal most research treats as informative. Code S is a sale, but sales are frequently pre-scheduled under a 10b5-1 plan or cover tax withholding on vesting equity, so a run of sales often says nothing directional. Codes A and M are grants and option exercises rather than open-market decisions.

Full filing history and per-insider positions are on the VYNE quote page; the site-wide leaderboard is on the insider transactions hub.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.