BBC vs LABU
Virtus Biotech Clinical Trials ETF against Direxion Daily S&P Biotech Bull 3X ETF: cost, size, returns, what they hold and how much of it is the same.
Overlap by weight
28%
75 shared positions
Fee gap
—
same fee
1-year return gap
70.6 pts
LABU is ahead
Larger fund
LABU
$553M
Side by side
| BBC | LABU | |
|---|---|---|
| Fund | Virtus Biotech Clinical Trials ETF | Direxion Daily S&P Biotech Bull 3X ETF |
| Issuer | Virtus | Direxion |
| Category | Biotech & Health Innovation | Leveraged Equity |
| Expense ratio | 0.65% | — |
| Assets | $42M | $553M |
| Average daily dollar volume | $866K | $105M |
| Listed | Dec 16, 2014 | May 28, 2015 |
| FrenzyCap score | 44 | 84 |
| 1-month return | −11.6% | −8.6% |
| 3-month return | −14.0% | −10.9% |
| Year to date | +14.5% | +52.5% |
| 1-year return | +52.3% | +123.0% |
| 30-day volatility | 32.2% | 81.8% |
| Worst drawdown, 1 year | −22.8% | −34.7% |
| Trailing 12-month yield | 1.49% | 0.37% |
| Holdings | 125 | 173 |
| Top 10 weight | 16.2% | 248.9% |
| Look-through P/E | — | — |
| Holdings vs fair value | +16.7% | +5.8% |
| Holdings above 200-day average | 46% | 62% |
| Net flow, latest 3 reported months | +$5.1M thru Jul 2026 | −$198M thru Jul 2026 |
| 30-day implied volatility | 43.3% | 94.0% |
| Holdings as of | as of Apr 30, 2026SEC filing | as of Oct 9, 2026issuer data |
Returns are price returns and exclude distributions. Flows are each fund's own latest reported months and may not cover the same period.
Largest shared holdings
62% of BBC · 30% of LABU| Holding | BBC | LABU |
|---|---|---|
| SYRE | 1.64% | 1.09% |
| RVMD | 1.35% | 1.07% |
| ERAS | 2.19% | 1.04% |
| ORKA | 1.68% | 1.00% |
| KOD | 1.35% | 0.97% |
| PCVX | 0.95% | 1.03% |
| DNTH | 1.54% | 0.91% |
| PRAX | 0.88% | 0.90% |
| CGON | 1.21% | 0.78% |
| PTGX | 0.77% | 1.13% |
| CYTK | 0.75% | 0.99% |
| TNGX | 1.71% | 0.73% |
| RLAY | 1.19% | 0.68% |
| BEAM | 0.82% | 0.68% |
| KYMR | 0.67% | 0.94% |
| CELC | 0.85% | 0.65% |
| COGT | 0.63% | 0.94% |
| VKTX | 0.62% | 0.76% |
| SRRK | 0.73% | 0.61% |
| DYN | 0.67% | 0.57% |
| RXRX | 0.59% | 0.53% |
| IMVT | 0.76% | 0.51% |
| SMMT | 0.90% | 0.50% |
| IDYA | 0.63% | 0.46% |
| DNLI | 0.77% | 0.46% |
Sector mix of the stock holdings
| Sector | BBC | LABU | Gap |
|---|---|---|---|
| Health Care | 92.6% | 77.2% | +15.4% |
| Technology | 0.6% | 0.0% | +0.6% |
| Financials | 0.0% | 0.5% | −0.5% |
More: full overlap table · BBC holdings · LABU holdings
Fund data comes from each fund's SEC filings and issuer disclosures and is shown with the date it is as of. SEC portfolio and flow filings become public about 60 days after the period they cover. Nothing here is investment advice; see Terms.