ETFs most similar to SBIO
The funds whose holdings overlap ALPS Medical Breakthroughs ETF the most, by weight. as of May 31, 2026SEC filing
By holdings overlap
| Fund | Category | Overlap with SBIO | Fee | Assets | 1Y | Yield | Compare |
|---|---|---|---|---|---|---|---|
| SBIOALPS Medical Breakthroughs ETF | Biotech & Health Innovation | — | 0.50% | $200M | +34.6% | — | |
| BBCVirtus Biotech Clinical Trials ETF | Biotech & Health Innovation | 31% | 0.65% | $42M | +52.3% | 1.49% | side by side |
| XBIState Street SPDR S&P Biotech ETF | Biotech & Health Innovation | 22% | 0.35% | $9.9B | +45.8% | 0.35% | side by side |
| IBRNiShares Neuroscience and Healthcare ETF | Biotech & Health Innovation | 19% | 0.47% | $6.4M | +13.3% | 1.01% | side by side |
| LABUDirexion Daily S&P Biotech Bull 3X ETF | Leveraged Equity | 18% | — | $553M | +123.0% | 0.37% | side by side |
| PTHInvesco Exchange-Traded Fund Trust Invesco Dorsey Wright Healthcare Momentum ETF | Health Care | 17% | 0.60% | $355M | +29.8% | 2.60% | side by side |
Overlap is the sum of the smaller of the two weights across every shared holding. Try any combination in the overlap tool.
Fund data comes from each fund's SEC filings and issuer disclosures and is shown with the date it is as of. SEC portfolio and flow filings become public about 60 days after the period they cover. Nothing here is investment advice; see Terms.