IRLA IRulya Therapeutics Inc.
XNAS
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
What changed
Recent filings, trades and moves
- Industry (SIC)
- BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836) · industry map
- Exchange
- XNAS
- Market Cap
- $0.4B
- Employees
- 38
- List Date
- 2019-05-09
- CIK
- 0001662774
- Next Earnings
- 2026-11-11
- EPS Forecast
- ($1.39)
- Headquarters
- South San Francisco, CA
- Homepage
- https://www.quincetx.com
IRulya Therapeutics Inc is committed to transforming the lives of patients with serious, underserved diseases by developing disease-modifying therapies. The company is currently developing LAM-001 for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD), bronchiolitis obliterans syndrome post-lung transplant (BOS), and sarcoidosis-associated pulmonary hypertension (SAPH). A Phase 2a study in PH patients has been completed; a Phase 2 clinical study in BOS patients is ongoing; a Phase 2b clinical study in PH-ILD is ongoing; and a Phase 2 clinical study in SA…
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Click Frenzy-Pro™ for an AI analysis of this ticker.
Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.
IRLA Options Activity & IV Rank
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
Calendars: the long leg is valued at the short leg’s expiration (Black-Scholes at its current IV) across the range of prices the short leg’s IV implies, giving the best-case profit (R/R = that over the debit) and P(profit).
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Scanning bull put, bear call, iron condor and calendar spreads…
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Loading the implied volatility surface…
Loading the implied volatility smile…
IRLA Institutional Ownership (13F)
Filings for 2026-06-30 · 6 already for 2026-09-30Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | TUDOR INVESTMENT CORP ET AL | $2.11M | 67.80% | 2026-06-30 |
| 2 | Susquehanna International Group, LLP Custodian | $1.00M | 32.20% | 2026-06-30 |
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | TUDOR INVESTMENT CORP ET AL | $2.14M | 100.00% | 2026-06-30 |
IRLA Board & Officers
As of SEC filings through Oct 19, 2026Directors 12
- Christopher J. Senner · since May 8, 2019
- David Lamond · since May 8, 2019
- Margaret McLoughlin · since May 8, 2019
- Una S Ryan · since May 8, 2019
- Dirk Thye · since May 19, 2022
- Luca Benatti · since Oct 23, 2023
- Rajiv Patni · since Feb 15, 2024
- Brigette Roberts · since May 18, 2026
- Catherine M. Bonuccelli · since Oct 8, 2026
- James Elwood Valentine · since Oct 8, 2026
- John Drayton Wise · since Oct 8, 2026
- Leone D Patterson · since Oct 8, 2026
Officers 5
- Dirk Thye · CEO and CMO · listed since Jun 2025
- Charles S. Ryan · President · since Sep 1, 2023
- John Militello · Chief Financial Officer · since Oct 8, 2026
- Keith R. Fandrick · Chief Operating Officer · since Oct 8, 2026
- Brigette Roberts · Chief Corp. Affairs Officer · since May 18, 2026
Changes in the last 10 years (69)
| Oct 8, 2026 | Leone D Patterson became a director |
| Oct 8, 2026 | Keith R. Fandrick became Chief Operating Officer |
| Oct 8, 2026 | John Militello became Chief Financial Officer |
| Oct 8, 2026 | John Drayton Wise became a director |
| Oct 8, 2026 | James Elwood Valentine became a director |
| Oct 8, 2026 | Catherine M. Bonuccelli became a director |
| Oct 7, 2026 | The company announced the departure of Brendan Hannah as Cbo, COO & Cco in an SEC filing |
| May 18, 2026 | Brigette Roberts became a director |
| May 18, 2026 | Brigette Roberts became Chief Corp. Affairs Officer |
| Jan 30, 2026 | The company announced the departure of June Bray from the board in an SEC filing |
| Jun 23, 2025 | Dirk Thye listed as CEO and CMO (previously CEO and Chief Medical Officer) in SEC filings |
| Feb 11, 2025 | Brendan Hannah listed as Cbo, COO & Cco (previously Chief Business Officer and COO) in SEC filings |
| Feb 15, 2024 | Rajiv Patni became a director |
| Feb 2, 2024 | Dirk Thye listed as CEO and Chief Medical Officer (previously Chief Executive Officer) in SEC filings |
| Oct 26, 2023 | Brendan Hannah listed as Chief Business Officer and COO (previously Chief Business Officer) in SEC filings |
| Oct 23, 2023 | Luca Benatti became a director |
| Oct 23, 2023 | Guenter Janhofer became Chief Scientific Officer |
| Sep 1, 2023 | Charles S. Ryan became President |
| Jul 24, 2023 | The company announced the departure of Karen L. Smith as Chief Medical Officer in an SEC filing |
| Mar 27, 2023 | The company announced the departure of Philip S Low from the board in an SEC filing |
| Mar 1, 2023 | The company announced the departure of Ted Monohon as Chief Accounting Officer & VP in an SEC filing |
| Sep 28, 2022 | The company announced the departure of Marwan Sabbagh from the board in an SEC filing |
| Jul 20, 2022 | The company announced the departure of Leslie Holsinger as EVP, Preclinical Development in an SEC filing |
| Jun 9, 2022 | June Bray became a director |
| Jun 8, 2022 | The company announced the departure of Christopher P. Lowe as COO & Chief Financial Officer in an SEC filing |
| May 20, 2022 | The company announced the departure of Caryn Gordon McDowell as Chief Legal & Adm. Officer in an SEC filing |
| May 19, 2022 | Philip S Low became a director |
| May 19, 2022 | Karen L. Smith became Chief Medical Officer |
| May 19, 2022 | Dirk Thye became a director |
| May 19, 2022 | Dirk Thye became Chief Executive Officer |
| May 19, 2022 | Brendan Hannah became Chief Business Officer |
| Apr 26, 2022 | The company announced the departure of Michael J. Detke as Chief Medical Officer in an SEC filing |
| Mar 14, 2022 | Marwan Sabbagh became a director |
| Mar 4, 2022 | Ted Monohon listed as Chief Accounting Officer & VP (previously Chief Accounting Officer) in SEC filings |
| Mar 4, 2022 | Leslie Holsinger listed as EVP, Preclinical Development (previously Executive Vice President) in SEC filings |
| Feb 1, 2022 | The company announced the departure of Casey Lynch from the board in an SEC filing |
| Feb 1, 2022 | The company announced the departure of Casey Lynch as Chief Executive Officer in an SEC filing |
| Jan 28, 2022 | The company announced the departure of Stephen S. Dominy from the board in an SEC filing |
| Feb 11, 2021 | Christopher P. Lowe listed as COO & Chief Financial Officer (previously Chief Financial Officer) in SEC filings |
| Feb 9, 2021 | Ted Monohon became Chief Accounting Officer |
| Jun 4, 2020 | Pfizer Ventures (US) LLC reported in an SEC filing no longer being a 10% owner |
| Jun 4, 2020 | Pfizer Strategic Investment Holdings LLC reported in an SEC filing no longer being a 10% owner |
| Jun 4, 2020 | Pfizer Inc reported in an SEC filing no longer being a 10% owner |
| May 5, 2020 | Caryn Gordon McDowell became Chief Legal & Adm. Officer |
| Aug 19, 2019 | Chad Boeding no longer listed as a 10% owner in SEC filings |
| Aug 15, 2019 | Kristen Gafric listed as SVP, Legal & Administration (previously VP Operations) in SEC filings |
| May 9, 2019 | Chad Boeding became a 10% owner |
| May 8, 2019 | Una S Ryan became a director |
| May 8, 2019 | Takeda Ventures, Inc. became a 10% owner |
| May 8, 2019 | Takeda Pharmaceuticals U.S.A., Inc. became a 10% owner |
| May 8, 2019 | Takeda Pharmaceuticals International AG became a 10% owner |
| May 8, 2019 | Takeda Pharmaceutical Co Ltd became a 10% owner |
| May 8, 2019 | Stephen S. Dominy became a director |
| May 8, 2019 | Stephen S. Dominy became Chief Scientific Officer |
| May 8, 2019 | Pierre Lamond became a 10% owner |
| May 8, 2019 | Pfizer Ventures (US) LLC became a 10% owner |
| May 8, 2019 | Pfizer Strategic Investment Holdings LLC became a 10% owner |
| May 8, 2019 | Pfizer Inc became a 10% owner |
| May 8, 2019 | Michael J. Detke became Chief Medical Officer |
| May 8, 2019 | Margaret McLoughlin became a director |
| May 8, 2019 | Leslie Holsinger became Executive Vice President |
| May 8, 2019 | Kristen Gafric became VP Operations |
| May 8, 2019 | Kevin Young became a director |
| May 8, 2019 | David Lamond became a director |
| May 8, 2019 | Christopher P. Lowe became Chief Financial Officer |
| May 8, 2019 | Christopher J. Senner became a director |
| May 8, 2019 | Christine Lamond became a 10% owner |
| May 8, 2019 | Casey Lynch became a director |
| May 8, 2019 | Casey Lynch became Chief Executive Officer |
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Not reported recently (10)
- Guenter Janhofer · Last reported as Chief Scientific Officer in an SEC filing dated Oct 24, 2023
- Stephen S. Dominy · Last reported as Chief Scientific Officer in an SEC filing dated Jan 5, 2022
- Kevin Young · Last reported as a director in an SEC filing dated Jun 9, 2020
- Kristen Gafric · Last reported as SVP, Legal & Administration in an SEC filing dated Feb 10, 2020
- Takeda Pharmaceuticals International AG · Last reported as a 10% owner in an SEC filing dated May 13, 2019
- Takeda Pharmaceutical Co Ltd · Last reported as a 10% owner in an SEC filing dated May 13, 2019
- Takeda Ventures, Inc. · Last reported as a 10% owner in an SEC filing dated May 13, 2019
- Takeda Pharmaceuticals U.S.A., Inc. · Last reported as a 10% owner in an SEC filing dated May 13, 2019
- Christine Lamond · Last reported as a 10% owner in an SEC filing dated May 13, 2019
- Pierre Lamond · Last reported as a 10% owner in an SEC filing dated May 13, 2019
IRLA Proposed Insider Sales (Form 144)
Latest: 2026-11-05What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.
How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.
10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.
"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.
Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.
| Filed | Filer | Role | Shares | Notice Value | Planned Sale | Broker | Plan | Link |
|---|---|---|---|---|---|---|---|---|
| 2026-11-05 | Blue Devil Trust | Former Board Member | 3,471 | $103.5K | 2026-10-09 | Merrill Lynch | — | EDGAR |
| 2026-10-21 | Dirk Thye | Officer | 3,700 | $133.3K | 2026-10-21 | MERRILL | — | EDGAR |
| 2025-12-29 | LUCA BENATTI | OFFICER | 50,000 | $173.2K | 2025-12-26 | MERRILL | — | EDGAR |
| Filing Date | Event | Link |
|---|---|---|
| 2026-10-19 | Regulation FD disclosure | EDGAR |
| 2026-10-09 | Director or officer change · Bylaws or fiscal year change · Regulation FD disclosure · Other events | EDGAR |
| 2026-10-06 | Director or officer change · Bylaws or fiscal year change · Shareholder vote results | EDGAR |
| 2026-10-02 | Director or officer change | EDGAR |
| 2026-09-14 | Acquisition or sale completed · Director or officer change | EDGAR |
| 2026-09-04 | Listing standards notice | EDGAR |
| 2026-08-27 | Director or officer change | EDGAR |
| 2026-08-17 | Other events | EDGAR |
| 2026-08-14 | Earnings results | EDGAR |
| 2026-07-31 | Director or officer change | EDGAR |
| Filing Date | Accession | Link |
|---|
| Filing Date | Accession | Link |
|---|---|---|
| 2026-08-14 | 0001193125-26-352201 | EDGAR |
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.
IRLA vs Peers
Related companies, largest first| Company | Market cap | P/E | Revenue growth | YTD | IV rank |
|---|---|---|---|---|---|
| AMGN Amgen Inc | $251.6B | 26.9 | +8.2% | +41.3% | 35 |
| GILD Gilead Sciences Inc | $210.0B | — | +6.5% | +39.7% | 45 |
| MRNA Moderna, Inc. Common Stock | $108.8B | — | −27.6% | +711.0% | 46 |
| ARGX argenx SE American Depositary Shares | $60.5B | — | — | +15.1% | 57 |
| RVMD Revolution Medicines, Inc. Common Stock | $43.3B | — | — | +143.2% | 59 |
| BIIB Biogen Inc. Common Stock | $37.7B | 107.6 | +2.3% | +41.6% | 100 |
| BNTX BioNTech SE American Depositary Share | $21.7B | — | — | −10.0% | 42 |
| EXEL Exelixis Inc | $17.5B | 21.0 | +9.1% | +61.3% | 23 |
| IRLA IRulya Therapeutics Inc. Common Stock | $366M | — | — | — | — |
| Peer median | $51.9B | 26.9 | +6.5% | +41.5% | 46 |
P/E uses the latest reported trailing-12-month diluted EPS; "—" means no positive earnings or no data.