DTIL Precision BioSciences, Inc.

XNAS 9.36 Delayed
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DTIL $9.36 —
Key stats
$9.36
52-Week Range
$3.53 – $11.29
YTD
+128.29%
Straddle Price
$3.72
P/C Vol Ratio
0.36
Market Cap
$0.3B
Open
$9.46
Day Range
$9.25 – $9.59
Volume
18,265
Prev Close
$9.50
Fair Value
MODEL: LONG

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.86%
Beta vs SPY1.21
Cost of Equity (CAPM)11.52% (VRP-adj)
WACC11.03%
Volatility Risk Premium+100.2pp (IV − HV30), ERP adj +50bps
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+3.0%
DCF Horizon10 years explicit + fade
Forward Tilt (NTM/TTM)×1.03 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$-0.1B
Return on Equity (TTM)-80.9%
Book / Price19.9%
Gross Margin (TTM)100.0%
FCF Margin (TTM)-171.7%
Debt / Equity0.43
Quality Score2/6 — normal (10y DCF)
SMA 50$6.97 (Market Anchor value)
SMA 20 / Bollinger Mid$7.39
Bollinger Width / SMA2074.6% (drives anchor stability)
Net Debt$-0.1B
Market Cap$0B
Peers used for multiples: CDNA, GH, GMAB, MRNA, QGEN, RVMD, TECH, VRTX
60-Day Conviction
70%
20-Day Fair Value
≈ by Dec 10, 2026
$9.27
α +0.2% rank 69%
conviction
15%
40-Day Fair Value
≈ by Jan 8, 2027
$9.73
α +5.2% rank 70%
conviction
97%
60-Day Fair Value
≈ by Feb 8, 2027
$9.52
α +3.0% rank 73%
conviction
70%
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0% median 35.1× · 3 peers
Peer EV/EBITDA n/a 0% median 32.6× · 3 peers
Peer P/B $17.91 18% median 9.5× · 5 peers
Peer P/S $17.72 18% median 13.8× · 6 peers
Market Anchor (SMA50) $6.97 64% stability 68% (BB-width)
Options Expected (B-L 30d) $6.85 0% 5 strikes · skew +2.00
As of 2026-11-11 · updated
About
Industry (SIC)
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836) · industry map
Exchange
XNAS
Market Cap
$0.3B
Employees
69
List Date
2019-03-28
CIK
0001357874
Last Earnings
Nov 3 before open · +0.3% vs ±73.7% expected
Next Earnings
~Jan 12, 2027 (estimated)
Headquarters
Durham, NC
Homepage
https://www.precisionbiosciences.com

Precision BioSciences Inc clinical stage gene editing company utilizing its proprietary ARCUS platform to concurrently develop two clinical-stage in vivo gene editing therapies. The ARCUS platform is used to develop in vivo gene editing therapies for sophisticated gene edits, including gene insertion (inserting DNA into gene to cause expression/add function), elimination (removing a genome, e.g. viral DNA), and excision (removing a large portion of a defective gene by delivering two ARCUS nucleases in a single adeno-associated virus ("AAV")).

Summary
—
composite
—
No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
Month'21'22'23'24'25'26Avg
Jan38.20%-38.53%-0.85%1.76%6.82%-3.41%0.67%
Feb-5.23%-13.62%-4.27%62.28%15.42%5.53%10.02%
Mar-19.58%-29.36%-32.71%6.60%-4.60%27.02%-8.77%
Apr-10.07%-39.70%8.46%-32.27%25.61%25.66%-3.72%
May14.46%-20.75%-13.20%23.09%-15.56%-4.26%-2.70%
Jun15.82%5.96%-31.42%-25.73%-16.67%11.97%-6.68%
Jul-22.12%-3.92%7.04%-3.64%15.01%-12.35%-3.33%
Aug26.59%12.59%-20.20%13.69%6.06%8.22%7.83%
Sep-15.70%-17.72%-29.92%-13.85%10.40%-18.06%-14.14%
Oct-18.61%0.00%-7.40%-5.93%50.00%11.53%4.93%
Nov-7.17%-2.84%-11.00%-19.18%-26.09%33.09%*-5.53%
Dec-14.15%-10.53%0.00%-44.54%-16.13%---17.07%
Total-32.31%-85.30%-79.66%-56.62%30.17%101.22%-20.42%
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $7.55
SMA 50: $7.00
SMA 200: $6.73
Current: $9.29
EMA 12: $8.56
EMA 26: $7.77
MACD: 0.7871 | Signal: 0.2923
BULLISH
ADX (14): 28.24
TREND
+DI: 37.28
−DI: 12.03

Momentum Oscillators

RSI (14): 64.48
NEUTRAL
Stoch %K: 64.00
Stoch %D: 71.06
Williams %R: -40.00

Volume & Volatility

BB Upper: $10.35
BB Lower: $4.75
NEUTRAL
OBV: 27,691,275
Vol SMA 20: 414,600
Vol ROC: -91.65%
ATR: $0.77
True Range: $0.34
HV 20: 113.6%
HV 30: 97.9%
HV 60: 82.0%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-11-12T00:00:00 – 2026-11-10T00:00:00
AI Analysis
Written before DTIL’s Nov 3 earnings report, so it doesn’t reflect the results.

LLM Stock Analysis Report

Executive Summary

Overall Assessment: NEUTRAL (Confidence Level: 6/10)

Key Drivers:

  • Technical indicators suggest a consolidation phase, with MACD in bearish territory
  • Recent news headlines have been mixed, with some highlighting the potential of gene editing therapeutics, while others focus on market trends and growth forecasts

Primary Risks:

  • Volatility has increased, with options market pricing a $5.25 move by expiration
  • Beta is above average, indicating amplification of market moves

2-3 Sentence Investment Thesis:

DTIL's recent price action appears to be driven by short-term market sentiment, rather than fundamental changes in its business or industry. As the company continues to navigate the rapidly evolving landscape of gene editing therapeutics, it may benefit from investors seeking exposure to this growth area.

Recent News Sentiment Impact:

The recent news headlines have had a mixed impact on DTIL's price action. The positive sentiment surrounding gene editing therapeutics and clinical trial pipeline developments has contributed to some upward momentum, while the market commentary and earnings forecast releases have led to consolidation and volatility.

Technical Analysis

Trend Direction: Range-bound (Short-term), Consolidation Phase (Medium-term)

Support/Resistance Levels:

  • Upper Bollinger Band: $7.81
  • Middle Line: $7.33
  • Lower Band: $6.84
  • Recent Low: $6.05

Momentum Signals:

  • RSI: 61.92 (Neutral)
  • MACD: Bearish (-0.00 / Signal: 0.06 / Histogram: -0.06)
  • Bollinger Bands: Overbought

Volume Analysis:

  • Volume SMA 20: 243406.15
  • OBV: 24111682.88
  • Volume Rate of Change: -68.75%

News & Sentiment Analysis

Recent Headlines Summary:

The recent news headlines have been focused on the potential of gene editing therapeutics, clinical trial pipeline developments, and market trends.

Sentiment Assessment:

Aggregate news sentiment is NEUTRAL, with some positive and neutral articles offset by more bearish commentary.

Catalyst Identification:

  • Upcoming events: Earnings releases, regulatory approvals
  • Product launches: Gene editing therapies

Market Narrative:

The recent news headlines have driven some short-term market momentum, but the overall narrative remains focused on the company's position within the rapidly evolving landscape of gene editing therapeutics.

Risk & Volatility Assessment

Risk Assessment:

  • Beta: 1.05 (above average)
  • Volatility: 0.70 (above average)
  • Options market pricing a $5.25 move by expiration

Downside Protection:

Support levels: Recent Low ($6.05), Middle Line ($7.33)

Market Context & Positioning

Sector Performance:

DTIL is outperforming its sector peers, with a relative strength of 1.15.

Institutional Activity:

  • Volume patterns suggest institutional interest, with some buying and selling activity.

Correlation Analysis:

DTIL has a moderate correlation (0.19) with the broader market (SPY).

Relative Valuation:

DTIL is positioned within its trading range, with recent price action driven by short-term market sentiment rather than fundamental changes in its business or industry.

Key Levels & Action Items

Critical Price Levels:

  • Support: Recent Low ($6.05), Middle Line ($7.33)
  • Resistance: Upper Bollinger Band ($7.81)

Breakout/Breakdown Levels:

  • Breakout above $7.81 could trigger further upward momentum
  • Breakdown below $6.05 could lead to increased volatility and potential short-term losses

Time-Sensitive Catalysts:

  • Earnings releases, regulatory approvals, product launches

Risk Management:

Stop-loss levels: Consider setting stops around recent lows ($6.05) or middle line ($7.33) Position sizing considerations: Take a cautious approach, given the above-average volatility and beta

Generated
Earnings History
10 of 14 under expected move
Avg Expected Move
94.63%
Avg Actual Move
3.24%
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2021-01-25 Pre-Market 22.39% 0.00% 0.00x Within
2021-03-18 Pre-Market 11.76% 7.63% 0.65x Within
2021-10-21 Pre-Market 0.55% 0.63% 1.15x Exceeded
2022-01-10 Pre-Market 0.70% 1.68% 2.40x Exceeded
2022-03-15 Pre-Market 9.95% 16.38% 1.65x Exceeded
2022-05-09 Pre-Market 1.37% 9.79% 7.15x Exceeded
2023-11-07 Pre-Market 495.35% 2.48% 0.01x Within
2024-03-27 Pre-Market 370.18% 1.80% 0.00x Within
2024-08-01 Pre-Market 76.60% 0.42% 0.01x Within
2026-01-13 Pre-Market 137.93% 1.23% 0.01x Within
2026-03-12 After-Close 21.60% 0.00% 0.00x Within
2026-05-05 Pre-Market 64.22% 2.36% 0.04x Within
2026-08-06 Pre-Market 38.49% 0.67% 0.02x Within
2026-11-03 Pre-Market 73.74% 0.29% 0.00x Within

Earnings calendar: this week’s reports with expected vs actual moves →

DTIL Options Activity & IV Rank

Volatility Metrics

Current IV: —
7-DTE IV: —
Expected Move: $3.72
7-DTE Move: $3.35
Days to Exp: 37 (2026-12-18)

Options Flow · All expiries

Call Volume: 298
Put Volume: 108
P/C Volume: 0.362
BULLISH
Call OI: 1,275
Put OI: 163
P/C OI: 0.128
Total OI: 1,438

ATM Options Pricing

ATM Call: $1.18
ATM Put: $2.55
Call %: 12.6%
Put %: 27.2%

Chain Summary

Chain Volume: 406
Chain OI: 1,438
Last Updated: 11/11/2026
Spread Scanner

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
Calendars: the long leg is valued at the short leg’s expiration (Black-Scholes at its current IV) across the range of prices the short leg’s IV implies, giving the best-case profit (R/R = that over the debit) and P(profit).

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Scanning bull put, bear call, iron condor and calendar spreads…

Dealer Positioning
LOW γ vs HISTORY

Estimated net dealer gamma is at the 2nd percentile of this name's own daily history, near the low end of its range. This describes current positioning; it is not a forecast or a trading signal.

Gamma percentile
2%
vs own history
GEX tilt
+0.09
OI-weighted, today
Vanna tilt
+0.33
δ-sensitivity to IV
Charm tilt
+0.02
δ-decay vs time
Vanna tilt +0.33: the estimated dealer exposure leans positive, so the modeled hedge would shift noticeably if implied volatility changed.

Net dealer gamma is an estimate of the aggregate gamma held by options market makers across this name's option chain, weighted by open interest. Dealer positions aren't public, so it uses a standard simplifying assumption: dealers are treated as long the calls and short the puts that are open. Actual dealer books can differ.

Gamma percentile ranks today's estimate against this name's own daily history, from 0% (the lowest reading on record) to 100% (the highest). Raw gamma scales with how much open interest a chain carries, so it isn't comparable across names; the percentile is. The badge marks the bottom 20% as low and the top 20% as high.

Tilts run from −1 to +1 and show how lopsided the estimated dealer exposure is. GEX tilt compares call gamma with put gamma. Vanna tilt describes how the hedge would shift if implied volatility changed, and charm tilt how it would shift with the passage of time.

This card describes estimated positioning and where it sits historically. It is not a forecast of price direction or volatility and not a trading signal. Market-wide view: Dealer positioning screener.

· 3 ATM contracts, 0k total OI
Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
No data
30 DTE / 10d —
— pts EXTREME
No data

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Loading the implied volatility surface…

Volatility Smile

Loading the implied volatility smile…

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)$3.72Nov 11
Beta Analysis

Risk Metrics

Beta: 0.4008
Alpha: 65.67%
Correlation: 0.0744
R-Squared: 0.6%
Stock Volatility: 73.7%
Market Volatility: 13.7%

Analysis Details

Benchmark: SPY
Data Points: 251
Period: 252 trading days
Interpretation:
Low volatility - stock moves less than market
Beta & Alpha Over Time
Notable investors who own DTIL
4 of 37 tracked investors
InvestorValueShare of their portfolioRankQ/Q sharesSource
Renaissance Technologies Hedge fund
Jim Simons
$539K
0.00%
#2579 of 3138-69.3%13F
Citadel Hedge fund
Ken Griffin
$539K
0.00%
#4388 of 6285-40.9%13F
Point72 Hedge fund
Steve Cohen
$111K
0.00%
#1833 of 1945-60.4%13F
Rockefeller Capital Management Family office
Rockefeller family
$8K
0.00%
#4102 of 47290.0%13F

Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions

DTIL Institutional Ownership (13F)

Filings for 2026-06-30 · 33 already for 2026-09-30
Diluted shares outstanding: 21,063,956 (as of 2026-09-30)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

101 filers17,593,409 shares$132.60M value83.52% of float
# Filer Shares Value % of Total % of Float Period
1 Bleichroeder LP 2,018,190 $15.86M 11.96% 9.58% 2026-06-30
2 Aberdeen Group plc 2,230,178 $13.96M 10.53% 10.59% 2026-09-30
3 Octagon Capital Advisors LP 1,350,000 $10.61M 8.00% 6.41% 2026-06-30
4 BOOTHBAY FUND MANAGEMENT, LLC 1,346,004 $10.58M 7.98% 6.39% 2026-06-30
5 BlackRock, Inc. Custodian 1,172,873 $9.22M 6.95% 5.57% 2026-06-30
6 Vanguard Capital Management LLC 1,116,241 $8.77M 6.62% 5.30% 2026-06-30
7 Lynx1 Capital Management LP 950,466 $7.47M 5.63% 4.51% 2026-06-30
8 Driehaus Capital Management LLC 946,707 $7.44M 5.61% 4.49% 2026-06-30
9 Empery Asset Management, LP 776,093 $6.10M 4.60% 3.68% 2026-06-30
10 Affinity Asset Advisors, LLC 646,576 $5.08M 3.83% 3.07% 2026-06-30
11 Geode Capital Management, LLC Custodian 634,158 $3.97M 2.99% 3.01% 2026-09-30
12 State Street Corp 427,325 $3.36M 2.53% 2.03% 2026-06-30
13 ACADIAN ASSET MANAGEMENT LLC 305,759 $2.40M 1.81% 1.45% 2026-06-30
14 ArrowMark Colorado Holdings LLC 274,140 $2.15M 1.62% 1.30% 2026-06-30
15 Corient Private Wealth LP 245,058 $1.93M 1.45% 1.16% 2026-06-30
16 Two Sigma Investments, LP Custodian 237,863 $1.87M 1.41% 1.13% 2026-06-30
17 Northern Trust Corp Custodian 190,188 $1.49M 1.13% 0.90% 2026-06-30
18 MACKENZIE FINANCIAL CORP 235,656 $1.48M 1.11% 1.12% 2026-09-30
19 JPMorgan Chase & Co Custodian 180,452 $1.43M 1.08% 0.86% 2026-06-30
20 Vanguard Fiduciary Trust Co 166,538 $1.31M 0.99% 0.79% 2026-06-30
21 Vanguard Portfolio Management LLC 161,782 $1.27M 0.96% 0.77% 2026-06-30
22 Goldman Sachs Group Inc Custodian 139,828 $1.10M 0.83% 0.66% 2026-06-30
23 Squarepoint Ops LLC 137,106 $1.08M 0.81% 0.65% 2026-06-30
24 Morgan Stanley Custodian 130,536 $1.03M 0.77% 0.62% 2026-06-30
25 Quarry LP 97,915 $769.61K 0.58% 0.46% 2026-06-30
2 filers$90.51K notional
# Filer Notional Value % of Total Period
1 Jane Street Group, LLC Custodian $81.74K 90.32% 2026-06-30
2 Simplex Trading, LLC Custodian $8.76K 9.68% 2026-09-30
1 filers$98.25K notional
# Filer Notional Value % of Total Period
1 Citadel Advisors LLC Custodian $98.25K 100.00% 2026-06-30

DTIL Insider Trading (Form 4)

Latest: 2026-09-30
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-09-30 Stanley Frankel Director Buy (P) +1,000 $6.00 $6.0K EDGAR
2026-09-29 Melinda Brown Director Buy (P) +1,135 $6.27 $7.1K EDGAR
2026-09-29 Geno J Germano Director Buy (P) +2,609 $6.28 $16.4K EDGAR
2026-06-05 Shari Lisa Pire Director Grant (A) +20,979 RSU — EDGAR
2026-06-05 Melinda Brown Director Grant (A) +20,979 RSU — EDGAR
2026-06-05 Stanley Frankel Director Grant (A) +20,979 RSU — EDGAR
2026-06-05 Kevin Buehler Director Grant (A) +20,979 RSU — EDGAR
2026-06-05 Geno J Germano Director Grant (A) +20,979 RSU — EDGAR
2026-06-03 Dario Scimeca General Counsel and Secretary Grant (A) +107,604 RSU — EDGAR
2026-06-03 John Alexander Kelly Chief Financial Officer Grant (A) +193,688 RSU — EDGAR
2026-06-03 Michael Amoroso President and CEO Grant (A) +573,888 RSU — EDGAR
2026-06-03 J. Jefferson Smith Chief Research Officer Grant (A) +57,389 RSU — EDGAR
2026-05-22 Kevin Buehler Director Exer (M) +21,000 — EDGAR
2026-05-22 Stanley Frankel Director Exer (M) +21,000 — EDGAR
2026-05-22 Shari Lisa Pire Director Exer (M) +21,000 — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.

DTIL Insider Holdings

9 insiders · @ $9.29
Officers, directors, and 10%+ owners who have filed a Form 4 in the past two years, ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Michael Amoroso President and CEO 263,951 $2.45M -$616.5K 21 2026-06-03
2 J. Jefferson Smith Chief Research Officer 129,857 $1.21M -$122.6K 16 2026-06-03
3 John Alexander Kelly Chief Financial Officer 125,883 $1.17M $88.3K 32 2026-06-03
4 Dario Scimeca General Counsel and Secretary 61,382 $570.2K -$169.1K 25 2026-06-03
5 Kevin Buehler Director 49,137 $456.5K $63.3K 15 2026-06-05
6 Geno J Germano Director 47,492 $441.2K $64.0K 13 2026-09-29
7 Melinda Brown Director 45,481 $422.5K $50.2K 13 2026-09-29
8 Stanley Frankel Director 41,478 $385.3K $32.1K 11 2026-09-30
9 Shari Lisa Pire Director 35,028 $325.4K $0 8 2026-06-05
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.

DTIL Board & Officers

As of SEC filings through Sep 30, 2026

Directors 6

Officers 6

  • Michael Amoroso · President and CEO · since Oct 15, 2021
  • Naresh Haresh Tanna · Chief Financial Officer · since Aug 1, 2026
  • J. Jefferson Smith · Chief Research Officer · listed since Sep 2022
  • Cassandra Louise Gorsuch · Chief Scientific Officer · since Aug 1, 2026
  • Dario Scimeca · General Counsel and Secretary · listed since Jun 2020
  • Mei Zhang Lu Burris · Chielf Accounting Officer · since Aug 1, 2026
Changes in the last 10 years (56)
Aug 1, 2026Naresh Haresh Tanna became Chief Financial Officer
Aug 1, 2026Mei Zhang Lu Burris became Chielf Accounting Officer
Aug 1, 2026Cassandra Louise Gorsuch became Chief Scientific Officer
Jan 23, 2025The company announced the departure of Samuel C. Wadsworth from the board in an SEC filing
Sep 9, 2024The company announced the departure of Alan List as Chief Medical Officer in an SEC filing
Aug 31, 2023The company announced the departure of Shane Barton as VP & Corporate Controller in an SEC filing
Sep 9, 2022J. Jefferson Smith no longer listed as a 10% owner in SEC filings
Sep 9, 2022J. Jefferson Smith first listed as Chief Research Officer in an SEC filing
Sep 1, 2022The company announced the departure of Derek Jantz from the board in an SEC filing
Jun 15, 2022Novartis Pharma Ag became a 10% owner
Jun 15, 2022Novartis Ag became a 10% owner
May 26, 2022Melinda Brown became a director
Nov 8, 2021Shari Lisa Pire became a director
Nov 8, 2021Samuel C. Wadsworth became a director
Oct 15, 2021Michael Amoroso became a director
Oct 15, 2021Michael Amoroso became President and CEO
Jun 9, 2021John Alexander Kelly listed as Chief Financial Officer (previously Interim CFO) in SEC filings
Apr 26, 2021Alan List became Chief Medical Officer
Apr 12, 2021Stanley Frankel became a director
Jan 1, 2021Shane Barton became VP & Corporate Controller
Not reported recently (12)
  • John Alexander Kelly · Last reported as Chief Financial Officer in an SEC filing dated Jun 3, 2026
  • Novartis Ag · Last reported as a 10% owner in an SEC filing dated Jun 27, 2022
  • Novartis Pharma Ag · Last reported as a 10% owner in an SEC filing dated Jun 27, 2022
  • Derek Jantz · Last reported as Chief Scientific Officer in an SEC filing dated Jun 9, 2022
  • Raymond F Schinazi · Last reported as a director in an SEC filing dated May 12, 2022
  • David S. Thomson · Last reported as Chief Operating Officer in an SEC filing dated Jun 25, 2021
  • Matthew R. Kane · Last reported as a director in an SEC filing dated Jun 11, 2021
  • Fayaz Khazi · Last reported as CEO of Elo Life Systems in an SEC filing dated Jun 9, 2021
  • Shalini Sharp · Last reported as a director in an SEC filing dated May 12, 2021
  • Abid Ansari · Last reported as Chief Financial Officer in an SEC filing dated Jun 17, 2020
  • Christopher Heery · Last reported as Chief Medical Officer in an SEC filing dated Jun 10, 2020
  • Tony Dung Ling Yao · Last reported as a director in an SEC filing dated Apr 4, 2019
Compiled from SEC filings by the company and its directors and officers. Dates are as stated in those filings. Where no filing says when someone left, we show the last filing that listed them.

DTIL Proposed Insider Sales (Form 144)

Latest: 2026-11-10
Last 30d: 3 filings · $109K notice value  ·  Last 90d: 3 filings · $109K notice value · 2 unique filers · 100% under 10b5-1 plans

What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.

How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.

10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.

"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.

Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.

Top 90-day filers: SMITH J. JEFFERSON (2, $81K) · Scimeca Dario (1, $28K)
Filed Filer Role Shares Notice Value Planned Sale Broker Plan Link
2026-11-10 Scimeca Dario Officer 2,821 $27.5K 2026-11-10 Fidelity Brokerage Services LLC 10b5-1 EDGAR
2026-11-06 SMITH J. JEFFERSON Officer 875 $9.0K 2026-11-06 Fidelity Brokerage Services LLC 10b5-1 EDGAR
2026-11-05 SMITH J. JEFFERSON Officer 7,056 $72.4K 2026-11-05 Fidelity Brokerage Services LLC 10b5-1 EDGAR
2026-02-18 SMITH J. JEFFERSON Officer 4,925 $18.9K 2026-02-18 Fidelity Brokerage Services LLC — EDGAR
2026-02-18 Scimeca Dario Officer 4,925 $18.9K 2026-02-18 Fidelity Brokerage Services LLC — EDGAR
2026-02-18 Amoroso Michael Officer, Director 20,559 $79.0K 2026-02-18 Fidelity Brokerage Services LLC — EDGAR
2026-02-18 Kelly John Alexander Officer 8,149 $31.3K 2026-02-18 Fidelity Brokerage Services LLC — EDGAR
2026-01-22 Amoroso Michael Officer, Director 34,799 $145.2K 2026-01-22 Fidelity Brokerage Services LLC — EDGAR
2026-01-21 Scimeca Dario Officer 8,854 $35.7K 2026-01-21 Fidelity Brokerage Services LLC — EDGAR
2026-01-21 SMITH J. JEFFERSON Officer 10,200 $41.1K 2026-01-21 Fidelity Brokerage Services LLC — EDGAR
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed. Market-wide feed: Planned sales (Form 144).
Recent SEC Filings
Latest: 2026-11-09
Current reports — material events the company must disclose within 4 business days (earnings releases, M&A, executive changes, etc.).
Filing Date Event Link
2026-11-09 Other events EDGAR
2026-11-06 Other events EDGAR
2026-11-05 Regulation FD disclosure · Other events EDGAR
2026-11-03 Earnings results EDGAR
2026-08-24 Regulation FD disclosure · Other events EDGAR
2026-08-06 Earnings results EDGAR
2026-07-27 Director or officer change · Regulation FD disclosure EDGAR
2026-07-01 Regulation FD disclosure · Other events EDGAR
2026-06-16 Material agreement · New debt obligation EDGAR
Annual report — audited financial statements, MD&A, risk factors. Filed 60–90 days after fiscal year-end.
Filing Date Accession Link
Quarterly report — unaudited financials and MD&A. Filed 40–45 days after each of the first three fiscal quarters.
Filing Date Accession Link
2026-11-03 0001628280-26-069092 EDGAR
2026-08-06 0001628280-26-053837 EDGAR
ETF Holders
25 ETFs hold DTIL
25 shown · $19.63M total exposure · 0.01% AUM-weighted avg weight
# ETF Provider Weight $ Exposure ETF AUM As Of
1 IWM iShares Russell 2000 ETF iShares (BlackRock) 0.01% $5.8M $77.8B 2026-11-09
2 VTI Vanguard Morningstar Total Stock Market ETF Vanguard 0.00% $4.9M — 2026-09-30
3 IWN iShares Russell 2000 Value ETF iShares (BlackRock) 0.02% $2.3M $14.1B 2026-11-09
4 VXF Vanguard Extended Market ETF Vanguard 0.00% $1.9M — 2026-09-30
5 FESM Fidelity Enhanced Small Cap Core ETF Fidelity 0.02% $1.2M $6.8B 2026-11-09
6 VTWO Vanguard Russell 2000 ETF Vanguard 0.00% $869,282 — 2026-09-30
7 IWC iShares Micro-Cap ETF iShares (BlackRock) 0.06% $708,218 $1.2B 2026-11-09
8 AVSC Avantis U.S. Small Cap Equity ETF Avantis 0.01% $355,140 $3.2B 2026-11-09
9 GSSC Goldman Sachs ActiveBeta U.S. Small Cap Equity ETF Goldman 0.03% $355,120 $1.1B 2026-11-09
10 DFAS Dimensional US Small Cap ETF Dimensional 0.00% $330,020 — 2026-11-09
11 DFMC Dimensional US Micro Cap ETF Dimensional 0.00% $222,843 — 2026-11-09
12 QQQS Invesco NASDAQ Future Gen 200 ETF Invesco 0.71% $149,053 — 2026-11-09
13 VTWV Vanguard Russell 2000 Value ETF Vanguard 0.01% $137,958 — 2026-09-30
14 RSSL Global X Russell 2000 ETF Global X 0.01% $110,257 — 2026-11-10
15 DXUV Dimensional US Vector Equity ETF Dimensional 0.00% $81,893 — 2026-11-09
16 DFAC Dimensional US Core Equity 2 ETF Dimensional 0.00% $56,396 — 2026-11-09
17 DCOR Dimensional US Core Equity 1 ETF Dimensional 0.00% $28,527 — 2026-11-09
18 DFAU Dimensional US Core Equity Market ETF Dimensional 0.00% $27,917 $12.9B 2026-11-09
19 VTHR Vanguard Russell 3000 ETF Vanguard 0.00% $13,897 — 2026-09-30
20 ITWO ProShares Russell 2000 High Income ETF ProShares 0.01% $12,711 — 2026-11-10
21 URTY ProShares UltraPro Russell2000 ProShares 0.00% $9,500 — 2026-11-10
22 UWM ProShares Ultra Russell2000 ProShares 0.00% $6,156 — 2026-11-10
23 GNMX Corgi Genomics & Precision Medicine ETF Corgi 0.39% $4,988 $1.3M 2026-11-10
24 HDG ProShares Hedge Replication ETF ProShares 0.00% $285 — 2026-11-10
25 RB ProShares Russell 2000 Dynamic Buffer ETF ProShares 0.01% $66 — 2026-11-10
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

Trailing P/E
—
TTM Diluted EPS
$-2.33
TTM Revenue
$34.22M
TTM Net Income
$-41.88M
TTM Op. Cash Flow
—
Quarterly figures (12 quarters)
QuarterPeriod EndRevenueNet IncomeDiluted EPSOp. Cash Flow
Q3 '262026-09-30$0.00$-7.59M$-0.28—
Q1 '272026-06-30—$-32.65M$-1.26—
Q1 '262026-03-31$10.84M$-18.44M$-0.75$-11.94M
Q4 '252025-12-31$34.20M$20.13M$2.58$-11.25M
Q3 '252025-09-30$13.00K$-21.77M$-1.84$-15.27M
Q1 '262025-06-30$18.00K$-23.52M$-2.13$-20.27M
Q1 '252025-03-31$29.00K$-20.57M$-2.21$-19.05M
Q4 '242024-12-31$638.00K$-17.75M$-2.74$-18.68M
Q3 '242024-09-30$576.00K$-16.43M$-2.25$-5.91M
Q2 '242024-06-30$49.90M$32.75M$4.67$-14.87M
Q1 '242024-03-31$17.58M$8.59M$1.70$-18.98M
Q4 '232023-12-31$7.04M$-16.29M$-4.06$-8.42M
Q3 2026 • period ending 2026-09-30 • filed 2026-11-03
Valuation

Ratios derived from TTM financials and the current market price, sampled daily. History chart shows how expensive the stock is today relative to its own recent past.

Price Multiples
  • P/E — price / TTM earnings. Rough market rule: 10–15 value, 15–25 market, >30 growth/premium. Negative when earnings are negative.
  • P/B — price / book value. Useful for financials and asset-heavy names; meaningless for asset-light software.
  • P/S — price / TTM revenue. Useful when earnings are negative or noisy (early-stage growth).
  • EV/EBITDA — capital-structure-neutral. <10 cheap, 10–15 reasonable, >20 rich. Good for comparing across leverage profiles.
  • EV/Sales — like P/S but accounts for debt + cash. Compare within sector.
Profitability & Yields
  • ROE — return on equity. >15% strong, >25% exceptional. Caution: high leverage inflates ROE.
  • ROA — return on assets. Leverage-neutral; >5% solid, >10% exceptional.
  • Div Yield — annual dividend / price. Compare to 10Y Treasury; sustained yield >6% often signals distress.
  • FCF Yield — free cash flow / market cap. >5% is attractive; negative means burning cash.
Balance Sheet
  • Debt/Equity — leverage. <1 conservative, >2 aggressive. Sector-dependent (utilities naturally high, tech low).
  • Current Ratio — short-term liquidity. >1.5 comfortable, <1 raises short-term solvency flags.
Reading the history chart
  • Compare current level to the 3-year band: near the high end = relatively expensive; near the low = relatively cheap.
  • Multiples expanding while earnings are flat = sentiment-driven rally.
  • Multiples compressing while earnings grow = value coming from fundamentals.
P/E
—
P/B
3.14
P/S
4.16
EV/EBITDA
—
EV/Sales
2.30
ROE
-127.6%
ROA
-45.9%
Div Yield
0.00%
FCF Yield
—
Debt/Equity
0.49
Current Ratio
—
Market Cap
$142.33M
as of 2026-11-11

DTIL vs Peers

Related companies, largest first
Company Market cap P/E Revenue growth YTD IV rank
VRTX Vertex Pharmaceuticals Inc $139.7B 34.8 +10.5% +19.6% 62
MRNA Moderna, Inc. Common Stock $108.8B — −27.6% +711.0% 46
RVMD Revolution Medicines, Inc. Common Stock $43.3B — — +143.2% 59
GMAB Genmab A/S ADS $34.3B — — +66.0% 15
GH Guardant Health, Inc. Common Stock $21.5B — +42.7% +57.5% 21
TECH Bio-Techne Corp. $11.4B 63.3 −0.4% +22.1% 36
QGEN QIAGEN N.V. $10.4B — — +11.4% 10
CDNA CareDx, Inc. $4.4B 34.8 +38.9% +334.8% 35
DTIL Precision BioSciences, Inc. Common Stock $270M — +4802.1% +126.6% 7
Peer median $27.9B 34.8 +10.5% +61.7% 36

P/E uses the latest reported trailing-12-month diluted EPS; "—" means no positive earnings or no data.

Short Interest & Float

Regulatory short-interest reports publish on a bi-weekly settlement cadence; short-volume is reported daily by the trade-reporting facilities. Float is derived from insider-ownership filings.

Metric definitions
  • Short Interest — total shares currently sold short as of the settlement date. Lags real time by ~8 business days.
  • SI % of Float — short interest / free float. The key crowding metric.
  • Days to Cover — short interest / avg daily volume. How many full trading days it would take shorts to buy back. High DTC + catalyst = squeeze fuel.
  • Short Vol Ratio — today's short-sale volume / total volume. Intraday selling pressure proxy (not the same as short interest).
  • Free Float — shares available for public trading (total shares minus insider / restricted).
  • Float % — free float / shares outstanding. <50% = tightly held, more prone to squeezes.
How to read the signals
  • SI % of Float < 5% — typical, no particular signal.
  • 5–15% — elevated; watch for catalysts (earnings, guidance, macro).
  • 15–30% — heavily shorted; tight-float names in this range have produced notable squeezes historically.
  • >30% — extreme; borrow is likely expensive and squeeze risk is material.
  • Days to Cover > 5 combined with high SI% amplifies squeeze potential.
History chart
  • Trend matters more than level. Rapidly rising short interest often precedes negative catalysts or heavy hedging.
  • A sudden drop in SI after a rally may indicate a squeeze in progress.

Short interest is reported mid-month and end-of-month; short volume is daily.

Short Interest
2.36M
SI % of Float
9.08%
Days to Cover
9.35
Short Vol Ratio
55.7%
Free Float
25.95M
Float %
94.0%
Short interest 2026-10-15 • Short volume 2026-11-10 • Float 2026-08-14