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SECTORAL ASSET MANAGEMENT INC — 13F Holdings & Portfolio

CIK 1274413 · latest 13F-HR filed 2026-08-14

Backtest portfolio

SECTORAL ASSET MANAGEMENT INC manages $143.3M in 13F-reported U.S. long-equity assets across 82 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are CTNM (8.32%), SI (6.09%), LLY (5.32%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 15 new positions and exited 10; 31 existing positions rose in reported value and 22 fell.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM
$143.3M

Long-equity book

Holdings
82

Distinct positions

Period
2026-06-30

Filed 2026-08-14

Q/Q Activity
+15 / −10 / ↑31 / ↓22

vs 2026-03-31

Portfolio charts

Latest quarter's book, what changed, and how the portfolio has evolved across filings.

Portfolio map

Q2 26
CTNM8.3% · 0%SI6.1% · 0%LLY5.3% · 0%UNH3.8% · -12%JNJ3.2% · 0%ORKA2.8% · newBNTX2.7% · +89%DFTX2.6% · newDXCM2.4% · +118%RCUS2.4% · +146%AMGN2.3% · 0%SMMT2.2% · +216%IRTC2.2% · newABBV2.1% · 0%MRK1.9% · 0%AVBP1.9% · +163%VRTX1.9% · -22%ARGX1.8% · -21%GILD1.8% · -25%INSM1.7% · +18%TECX1.7% · +273%ISRG1.6% · +11%IMTX1.6% · +237%SYK1.6% · +21%AVTX1.5% · newCBIO1.5% · newROIV1.5% · +88%IQV1.5% · +31%PLSE1.3% · newDHR1.3% · 0%TMO1.2% · 0%ABT1.1% · -29%ATEC1.1% · newBSX1.1% · +4%TMDX1.0% · newCYTK1.0% · +124%REGN0.9% · -26%CVS0.9% · newEW0.9% · -14%TRVI0.9% · -12%BMY0.8% · 0%VERA0.8% · 0%COGT0.7% · +21%MDT0.6% · 0%TARS0.6% · +18%KURA0.5% · 0%CNC0.5% · newUTHR0.5% · -20%HNGE0.5% · -29%NKTR0.5% · -7%ALNY0.5% · 0%ASND0.5% · -8%PFE0.5% · 0%ARDX0.4% · 0%PRVA0.4% · -11%PTCT0.4% · +12%IONS0.4% · 0%AGMB0.4% · 0%BMRN0.4% · 0%ONC0.4% · 0%

Box size = position value; colour = change in share count vs the prior quarter (green added, red trimmed, blue new). Rows split across managers or share classes are combined. Click a box for the stock.

Sector mix

% of 13F value

Sectors from each company's SIC code; funds and ETFs grouped separately.

Biggest buys and sells

Q1 26 → Q2 26

Estimated from the change in shares held × the quarter-end price, so price moves alone don't count as buying. New and exited positions are included.

13F assets and positions

4 quarters

Total reported 13F value (bars) and number of positions (line) each quarter. Value changes include market moves.

Top positions over time

reported value

The eight largest current positions, valued at each quarter end.

Concentration

top 10 = 39.6%

Cumulative share of the portfolio held in the largest N positions.

Firm Profile & Key People
Assets Under Management
$331.4M
Discretionary
$331.4M
Employees
20
Accounts
8
Address
1010 SHERBROOKE STREET, WEST
SUITE 1610
MONTREAL, QUEBEC H3A 2R7
Canada
Phone
(514) 849-8777
Website
Name Title / Status Ownership Type
LALAKIN, MARINA ControlCHIEF COMPLIANCE OFFICERLess than 5%Individual
Marcotte, Marc-Andre ControlPARTNER & HEAD OF VENTURE CAPITALLess than 5%Individual
PFUND, JEROME, GEORGES ControlCO-FOUNDER AND CEOLess than 5%Individual
PFUND, JEROME, GEORGES ControlSHAREHOLDER75% or moreIndividual
SECTORAL ASSET MANAGEMENT HOLDING LTD. ControlSHAREHOLDER75% or moreForeign Entity

Quarter-over-quarter changes

Changes in reported position value vs the prior 13F, so price moves count too, not just shares bought or sold.

SECTORAL ASSET MANAGEMENT INC Holdings (2026-06-30)

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 CONTINEUM THERAPEUTICS CTNM 21217B100 $11.9M 8.32% 727,587 SH
2 SHOULDER INNOVATIONS SI 82537J108 $8.7M 6.09% 430,407 SH
3 ELI LILLY & CO LLY 532457108 $7.6M 5.32% 6,354 SH
4 UNITEDHEALTH GRP INC UNH 91324P102 $5.5M 3.84% 13,235 SH
5 JOHNSON & JOHNSON JNJ 478160104 $4.6M 3.23% 18,218 SH
6 ORUKA THERAPEUTICS INC ORKA 687604108 $4.0M 2.79% 41,987 SH
7 BIONTECH SE BNTX 09075V102 $3.9M 2.72% 41,869 SH
8 DEFINIUM THERAPEUTICS INC DFTX 24477V105 $3.7M 2.57% 78,310 SH
9 DEXCOM INC DXCM 252131107 $3.4M 2.39% 50,756 SH
10 ARCUS BIOSCIENCES RCUS 03969F109 $3.4M 2.39% 110,870 SH
11 AMGEN INC AMGN 031162100 $3.3M 2.33% 9,210 SH
12 SUMMIT THERAPEUTICS SMMT 86627T108 $3.2M 2.24% 220,180 SH
13 IRHYTHM HOLDINGS INC IRTC 450056106 $3.1M 2.16% 26,070 SH
14 ABBVIE INC ABBV 00287Y109 $3.1M 2.14% 12,200 SH
15 MERCK & CO INC MRK 58933Y105 $2.8M 1.94% 21,480 SH
16 ARRIVENT BIOPHARMA AVBP 04272N102 $2.7M 1.92% 79,043 SH
17 VERTEX PHARMA VRTX 92532F100 $2.7M 1.88% 5,432 SH
18 ARGENX SE ARGX 04016X101 $2.6M 1.83% 2,831 SH
19 GILEAD SCIENCES INC GILD 375558103 $2.6M 1.82% 20,620 SH
20 INSMED INC INSM 457669307 $2.5M 1.73% 23,216 SH
21 TECTONIC THERAPEUTIC TECX 878972108 $2.4M 1.70% 71,009 SH
22 INTUITIVE SURGIC INC ISRG 46120E602 $2.3M 1.62% 5,850 SH
23 IMMATICS NV IMTX N44445109 $2.3M 1.59% 224,928 SH
24 STRYKER CORP SYK 863667101 $2.2M 1.57% 7,129 SH
25 AVALO THERAPEUTICS INC AVTX 05338F306 $2.2M 1.55% 119,923 SH
26 CRESCENT BIOPHARMA INC. CBIO G2545C104 $2.2M 1.52% 121,300 SH
27 ROIVANT SCIENCES LTD ROIV G76279101 $2.2M 1.51% 61,100 SH
28 IQVIA HOLDINGS INC IQV 46266C105 $2.1M 1.46% 10,848 SH
29 PULSE BIOSCIENCES INC PLSE 74587B101 $1.9M 1.31% 67,895 SH
30 DANAHER CORP DHR 235851102 $1.8M 1.28% 9,597 SH
31 THERMO FISHER SCIENTIFIC TMO 883556102 $1.8M 1.23% 3,508 SH
32 ABBOTT LABS ABT 002824100 $1.6M 1.14% 18,080 SH
33 ALPHATEC HLDGS INC ATEC 02081G201 $1.6M 1.12% 185,900 SH
34 BOSTON SCIENTIFIC BSX 101137107 $1.6M 1.08% 36,330 SH
35 TRANSMEDICS GROUP INC TMDX 89377M109 $1.5M 1.02% 21,950 SH
36 CYTOKINETICS INC CYTK 23282W605 $1.4M 0.97% 16,330 SH
37 REGENERON PHARMCTCLS REGN 75886F107 $1.4M 0.94% 2,169 SH
38 CVS HEALTH CORP CVS 126650100 $1.3M 0.94% 13,000 SH
39 EDWARDS LIFESCIENCES EW 28176E108 $1.3M 0.94% 14,826 SH
40 TREVI THERAPEUTICS TRVI 89532M101 $1.2M 0.85% 65,596 SH
41 BRISTOL MYERS SQUIBB BMY 110122108 $1.2M 0.85% 21,150 SH
42 VERA THERAPEUTICS VERA 92337R101 $1.1M 0.77% 25,573 SH
43 COGENT BIOSCIENCES COGT 19240Q201 $1.0M 0.72% 26,740 SH
44 MEDTRONIC PLC MDT G5960L103 $876.3K 0.61% 11,100 SH
45 TARSUS PHARMACEUTICALS TARS 87650L103 $836.2K 0.58% 13,285 SH
46 KURA ONCOLOGY INC KURA 50127T109 $784.1K 0.55% 71,480 SH
47 CENTENE CORP DEL CNC 15135B101 $770.3K 0.54% 12,000 SH
48 UNITED THERAPEUTICS UTHR 91307C102 $742.3K 0.52% 1,370 SH
49 HINGE HEALTH INC HNGE 433313103 $725.8K 0.51% 8,744 SH
50 NEKTAR THERAPEUTICS NKTR 640268306 $705.8K 0.49% 10,111 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-14 $143.3M 82 0001104659-26-096554
2026-03-31 2026-05-15 $120.7M 77 0001104659-26-062046
2025-12-31 2026-02-09 $124.8M 74 0001104659-26-011921
2025-09-30 2025-11-14 $162.0M 82 0001104659-25-112082
Filer Information
Address
1010 SHERBROOKE ST., WEST
SUITE 1610
MONTREAL, A8 H3A 2R7
Phone
(514) 849-8777
Filing Manager
SECTORAL ASSET MANAGEMENT INC
MONTREAL, A8
Signatory
Jerome Pfund
Co-Founder, CEO & CCO