CBIO Crescent Biopharma, Inc. Common Stock
XNAS
11.84
Delayed
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Expected move IV rank history Fibonacci levels Insider trading
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
CBIO
$11.84
—
Key stats
$11.84
- 52-Week Range
- $8.72 – $27.41
- YTD
- +6.86%
- IV Rank (30D)
- 66.93
- Straddle Price
- $4.95
- P/C Vol Ratio
- 1.33
- Market Cap
- $0.5B
- Open
- $12.73
- Day Range
- $11.78 – $12.73
- Volume
- 208,178
- Prev Close
- $12.48
Fair Value
MODEL: LONG
A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.
- DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
- Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
- DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
- P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
- Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
- Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
- Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
- Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
| 10-yr Treasury (rf) | 5.21% |
| Beta vs SPY | 1.83 |
| Cost of Equity (CAPM) | 15.27% (VRP-adj) |
| WACC | 15.26% |
| Volatility Risk Premium | +83.4pp (IV − HV30), ERP adj +50bps |
| Effective Tax Rate | 21.0% |
| Rev. Growth (YoY, DCF input) | +3.0% |
| DCF Horizon | 10 years explicit + fade |
| Forward Tilt (NTM/TTM) | ×1.03 (applied to P/E, EV/EBITDA, P/S) |
| Free Cash Flow (TTM) | $-0.1B |
| Return on Equity (TTM) | -89.4% |
| Book / Price | 59.5% — banking bias active (P/B is primary) |
| Gross Margin (TTM) | 100.0% |
| FCF Margin (TTM) | -619.5% |
| Debt / Equity | 0.00 |
| Quality Score | 2/6 — normal (10y DCF) |
| SMA 50 | $16.46 (Market Anchor value) |
| SMA 20 / Bollinger Mid | $14.35 |
| Bollinger Width / SMA20 | 219.3% (drives anchor stability) |
| Net Debt | $-0.2B |
| Market Cap | $0B |
Peers used for multiples: ABT, NVS, PFE
(SIC-code peers; ETF co-membership was sector-incoherent)
60-Day Conviction
97%
20-Day Fair Value
≈ by Nov 16, 2026
$12.05
α +1.8%
rank 73%
conviction
85%
40-Day Fair Value
≈ by Dec 15, 2026
$12.39
α +4.7%
rank 77%
conviction
96%
60-Day Fair Value
≈ by Jan 13, 2027
$12.44
α +5.0%
rank 73%
conviction
97%
| Method | Implied Price | Weight | Detail |
|---|---|---|---|
| DCF | n/a | 0% | |
| DDM (Gordon) | n/a | 0% | |
| Peer P/E | n/a | 0% | median 38.4× · 3 peers |
| Peer EV/EBITDA | n/a | 0% | median 19.1× · 3 peers |
| Peer P/B | $25.93 | 29% | median 3.5× · 3 peers |
| Peer P/S | $2.13 | 29% | median 3.8× · 3 peers |
| Market Anchor (SMA50) | $16.46 | 0% | stability 0% (BB-width) |
| Options Expected (B-L 30d) | $11.31 | 41% | 11 strikes · skew +0.44 |
As of 2026-10-16 · updated
Related
About
- Industry (SIC)
- PHARMACEUTICAL PREPARATIONS (2834) · industry map
- Exchange
- XNAS
- Market Cap
- $0.5B
- Employees
- 44
- List Date
- 2025-06-16
- CIK
- 0001253689
- Next Earnings
- 2026-11-05
- EPS Forecast
- ($0.72) (5 est.)
- Headquarters
- Waltham, MA
- Homepage
- https://www.crescentbiopharma.com
Crescent Biopharma Inc is a biopharmaceutical company developing novel therapeutics to treat solid tumors, led by CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody. Crescent's pipeline product CR-001 has the potential to deliver improved clinical efficacy and safety over pembrolizumab. CR-001 is a new molecular entity designed to replicate the functional properties of ivonescimab, a cooperative bispecific anti-PD-1/anti-VEGF antibody in development by Akeso Biopharma and Summit Therapeutics that delivered improved efficacy in a head-to-head Phase 3 clinical trial versus Keytruda in…
Summary
—
composite
—
No summary data available for this symbol yet.
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
Chart
Seasonality
| Month | '21 | '22 | '23 | '25 | '26 | Avg |
|---|---|---|---|---|---|---|
| Jan | -8.28% | -42.00% | -51.88% | -- | -13.45% | -28.90% |
| Feb | 3.79% | 7.20% | 5.32% | -- | 23.12% | 9.86% |
| Mar | -19.10% | 1.54% | -16.06% | -- | 64.02% | 7.60% |
| Apr | -5.44% | -27.44% | 0.95% | -- | 15.79% | -4.04% |
| May | -14.43% | 162.66% | 9.51% | -- | 14.28% | 43.00% |
| Jun | -0.23% | 49.58% | 65.30% | 2.18% | -8.72% | 21.62% |
| Jul | -6.44% | -2.23% | 8.29% | -23.10% | -16.93% | -8.08% |
| Aug | 10.63% | 11.30% | 55.04% | 20.00% | 11.63% | 21.72% |
| Sep | -14.73% | -74.42% | 6.07% | -13.08% | -18.63% | -22.96% |
| Oct | -18.97% | 3.69% | 4.37% | 7.14% | -16.97%* | -4.15% |
| Nov | -63.64% | -0.09% | -- | 21.86% | -- | -13.96% |
| Dec | -20.52% | -4.09% | -- | -16.89% | -- | -13.83% |
| Total | -87.15% | -50.22% | 44.49% | -11.07% | 32.26% | -14.34% |
Technical Indicators
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
Trend Indicators
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
Volume & Volatility
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
SMA 20: $14.09
SMA 50: $16.37
SMA 200: $15.79
Current: $11.84
EMA 12: $13.51
EMA 26: $14.65
MACD: -1.1376 | Signal: -0.1519
BEARISH
ADX (14): 21.22
WEAK TREND
+DI: 13.68
−DI: 27.34
Momentum Oscillators
RSI (14): 29.28
OVERSOLD
Stoch %K: 7.30
Stoch %D: 11.19
Williams %R: -98.44
Volume & Volatility
BB Upper: $16.28
BB Lower: $11.90
OVERSOLD
OBV: 2,263,185
Vol SMA 20: 376,430
Vol ROC: -26.52%
ATR: $1.19
True Range: $0.95
HV 20: 75.9%
HV 30: 68.0%
HV 60: 74.8%
Data Summary
Data Points: 500
Last Updated:
Date Range: 2023-03-09T00:00:00 – 2026-10-16T00:00:00
AI Analysis
LLM Stock Analysis Report: CBIO
Executive Summary
Overall Assessment: NEUTRAL (Confidence Level: 6/10) Key Drivers:
- Strong technical indicators, with RSI in neutral zone
- Supportive momentum signals from MACD and Bollinger Bands
- Low risk profile, with beta indicating low volatility
Primary Risks:
- Bearish momentum signal from MACD histogram
- Recent news headlines have been neutral, with no significant market-moving events
Investment Thesis: CBIO presents a cautiously optimistic opportunity, driven by technical indicators and low risk profile. However, the bearish momentum signal from MACD warrants caution.
Recent News Sentiment Impact: Neutral news headlines have not had a significant impact on the stock price.
Technical Analysis
Trend Direction:
- Short-term (1-4 weeks): Neutral to Bullish
- Medium-term (1-3 months): Bullish
- Long-term (3-12 months): Neutral
Support/Resistance Levels:
- Upper Bollinger Band: $18.64
- Middle Line: $17.58
- Lower Bollinger Band: $16.53
Momentum Signals:
- RSI: 46.28 (neutral)
- MACD histogram: -0.44 (bearish momentum)
- Bollinger Bands position: neutral (signal)
Volume Analysis:
- Volume SMA 20: 363382.00
- On-Balance Volume (OBV): 777525.84
- Volume Rate of Change: 66.02%
News & Sentiment Analysis
Recent Headlines Summary: Neutral news headlines with no significant market-moving events.
Sentiment Assessment: Neutral sentiment overall, with no dominant positive or negative themes.
Catalyst Identification: No upcoming events or regulatory changes that could significantly impact the stock price.
Market Narrative: Technical indicators and momentum signals are driving the stock price, while recent news headlines have been neutral.
Risk & Volatility Assessment
Risk Profile:
- Beta: 0.67 (low volatility)
- Alpha: 0.42
- Correlation: 0.11
Volatility Regime:
- Historical volatility: HV20 46.1%, HV30 65.8%, HV60 89.3%
- IV Premium vs HV30: -100.0% (positive)
Options Market Signals:
- IV Rank: 0.0% (Low)
- Current IV: 0.0%
- Expected Move: $2.00 (0 DTE), 7-DTE: $2.00
- Volume Flow: 20 calls vs 0 puts
- Open Interest: 2,772 calls vs 48 puts
Downside Protection:
- Support levels: Lower Bollinger Band ($16.53), SMA 200 ($14.60)
- Risk management considerations: Stop-loss levels and position sizing considerations based on technical indicators and risk profile.
Market Context & Positioning
Sector Performance:
- Relative strength vs sector/market: Neutral
Institutional Activity:
- Volume patterns suggesting institutional interest: Moderate volume flow (363382.00) with some institutional buying/selling activity.
Correlation Analysis:
- R-squared interpretation: Low correlation with market, indicating a relatively independent price movement.
Relative Valuation:
- Position within trading range: Bullish momentum signals suggest the stock is in an uptrend, while recent news headlines have been neutral.
Key Levels & Action Items
Critical Price Levels:
- Support levels: Lower Bollinger Band ($16.53), SMA 200 ($14.60)
- Resistance levels: Upper Bollinger Band ($18.64)
Breakout/Breakdown Levels:
- Technical levels that could trigger significant moves: MACD crossover above signal line (bullish) or below (bearish)
Time-Sensitive Catalysts:
- Earnings dates: No upcoming earnings data available
- FDA approvals: No recent approvals
Risk Management:
- Stop-loss levels and position sizing considerations based on technical indicators and risk profile.
Please note that this analysis is based on the provided data, and actual market conditions may vary. As a professional financial analyst, I would recommend further research and due diligence before making any investment decisions.
Generated
News
All CBIO news →
Earnings History
4 of 4 under expected move
Avg Expected Move
17.49%
Avg Actual Move
3.25%
| Earnings Date | Timing | Expected Move | Actual Move | Ratio | Outcome |
|---|---|---|---|---|---|
| 2022-03-03 | unknown | 19.36% | 8.02% | 0.41x | Within |
| 2022-08-03 | unknown | 2.75% | 1.10% | 0.40x | Within |
| 2025-11-06 | unknown | 14.89% | 0.23% | 0.02x | Within |
| 2026-07-30 | unknown | 32.96% | 3.66% | 0.11x | Within |
Earnings calendar: this week’s reports with expected vs actual moves →
CBIO Options Activity & IV Rank
CBIO IV rank history, 52-week IV rank and IV percentile →
Volatility Metrics
Current IV: 131.7%
7-DTE IV: —
Expected Move: $4.95
7-DTE Move: $4.90
Days to Exp: 35 (2026-11-20)
Options Flow
Call Volume: 3
Put Volume: 4
P/C Volume: 1.333
BEARISH
Call OI: 11
Put OI: 7
P/C OI: 0.636
Total OI: 18
ATM Options Pricing
ATM Call: $2.45
ATM Put: $2.50
Call %: 20.7%
Put %: 21.1%
Chain Summary
Chain Volume: 139
Chain OI: 3,078
Last Updated: 10/16/2026
Spread Scanner GPU
Each spread is ranked by a composite score built in three stages. Full documentation →
Stage 1 — Base Score (GPU scanner)
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
Stage 2 — Skew Adjustment (±25% cap)
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Wing vs ATM
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d
—
—
pts
EXTREME
No data
30 DTE / 10d
—
—
pts
EXTREME
ATM 144.9% / Wing —
Extreme reading.
Historically these have been contrarian — on the small set of observed earnings-day cases, large negative wing-vs-ATM gaps (calls pricing much richer than puts at the same delta) preceded sharp drops in the underlying within 1-12 days. Not financial advice and the dataset is small.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Volatility Surface
Enter a ticker to render the implied volatility surface.
Volatility Smile
Enter a ticker to render the implied volatility smile.
IV Rank (7 DTE)
IV Rank (30 DTE)66.9MediumOct 16
Straddle Price (30 DTE)$4.95Oct 16
Beta Analysis
Risk Metrics
Beta: 0.9051
Alpha: 13.46%
Correlation: 0.1443
R-Squared: 2.1%
Stock Volatility: 79.9%
Market Volatility: 12.7%
Analysis Details
Benchmark: SPY
Data Points: 251
Period: 252 trading days
Data Points: 251
Period: 252 trading days
Interpretation:
Moderate volatility - stock generally follows market
Moderate volatility - stock generally follows market
Beta & Alpha Over Time
Notable investors who own CBIO
2 of 37 tracked investors
| Investor | Value | Share of their portfolio | Rank | Q/Q shares | Source |
|---|---|---|---|---|---|
| Millennium Management Hedge fund Izzy Englander | $7.3M | #1814 of 3716 | +24.8% | 13F | |
| Point72 Hedge fund Steve Cohen | $5.4M | #956 of 1945 | 0.0% | 13F |
Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions
CBIO Institutional Ownership (13F)
Latest filings — 2026-09-30
? 13F Guide
Diluted shares outstanding: 21,971,857 (as of 2026-06-30)
Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|
| # | Filer | Notional Value | % of Total | Period |
|---|
CBIO Insider Trading (Form 4)
Latest: 2023-10-31Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2023-10-31 | GNI Group Ltd. | 10%+ Owner | Buy (P) | +16,222,222 RSU | — | EDGAR | |
| 2023-10-27 | GNI Hong Kong Ltd | 10%+ Owner | Other (J) | −5,371,304 | — | EDGAR | |
| 2023-09-01 | Seline E. Miller | SVP Finance; Interim CFO & PAO | Disp (D) | −6 | — | EDGAR | |
| 2023-09-01 | Augustine Lawlor | Director | Disp (D) | −48 | — | EDGAR | |
| 2023-09-01 | Nassim Usman | President & CEO | Disp (D) | −34 | — | EDGAR | |
| 2023-09-01 | Andrea Hunt | Director | Disp (D) | −28 | — | EDGAR | |
| 2023-09-01 | GNI Group Ltd. | 10%+ Owner | Disp (D) | −12,533 | — | EDGAR | |
| 2022-08-10 | Grant E. Blouse | Chief Scientific Officer | Buy (P) | +3,250 | $0.47 | $1.5K | EDGAR |
| 2022-08-10 | Seline E. Miller | SVP Finance; Interim CFO & PAO | Buy (P) | +3,250 | $0.47 | $1.5K | EDGAR |
| 2022-08-10 | Nassim Usman | President & CEO | Buy (P) | +3,250 | $0.47 | $1.5K | EDGAR |
| 2022-02-23 | Seline E. Miller | SVP Finance; Interim CFO & PAO | Grant (A) | +107,500 opt | — | EDGAR | |
| 2022-02-23 | Grant E. Blouse | Chief Scientific Officer | Grant (A) | +200,000 opt | — | EDGAR | |
| 2022-02-16 | Seline E. Miller | SVP Finance; Interim CFO & PAO | Buy (P) | +3,250 | $0.46 | $1.5K | EDGAR |
| 2022-02-16 | Grant E. Blouse | Chief Scientific Officer | Buy (P) | +3,250 | $0.46 | $1.5K | EDGAR |
| 2022-02-16 | Nassim Usman | President & CEO | Buy (P) | +3,250 | $0.46 | $1.5K | EDGAR |
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
CBIO Proposed Insider Sales (Form 144)
Latest: 2026-09-17
? Form 144 Guide
Last 30d:
4 filings
· $279K notice value
· Last 90d:
4 filings
· $279K notice value
· 2 unique filers
· 100% under 10b5-1 plans
What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.
How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.
10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.
"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.
Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.
Top 90-day filers:
Joshua T Brumm (2, $188K) · Jonathan McNeill (2, $91K)
| Filed | Filer | Role | Shares | Notice Value | Planned Sale | Broker | Plan | Link |
|---|---|---|---|---|---|---|---|---|
| 2026-09-17 | Joshua T Brumm | Officer, Director | 9,013 | $154.8K | 2026-09-18 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2026-09-17 | Jonathan McNeill | Officer | 4,415 | $75.8K | 2026-09-18 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2026-09-16 | Jonathan McNeill | Officer | 804 | $15.1K | 2026-09-16 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2026-09-16 | Joshua T Brumm | Officer, Director | 1,771 | $33.3K | 2026-09-16 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2023-05-17 | Hahn Brian M. | Officer | 4,313 | — | 2023-05-17 | Merrill Lynch | — | EDGAR |
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed. Market-wide feed: Planned sales (Form 144).
ETF Holders
20 ETFs hold CBIO
20 shown · $41.35M total exposure · 0.01% AUM-weighted avg weight
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|---|---|---|---|---|---|
| 1 | VTI Vanguard Morningstar Total Stock Market ETF | Vanguard | 0.00% | $13.2M | — | 2026-09-30 |
| 2 | IWM iShares Russell 2000 ETF | iShares (BlackRock) | 0.01% | $9.6M | $78.9B | 2026-10-14 |
| 3 | VXF Vanguard Extended Market ETF | Vanguard | 0.01% | $4.9M | — | 2026-09-30 |
| 4 | XBI State Street® SPDR® S&P® Biotech ETF | SPDR (State Street) | 0.04% | $4.4M | $10.1B | 2026-10-14 |
| 5 | IWO iShares Russell 2000 Growth ETF | iShares (BlackRock) | 0.03% | $3.4M | $13.6B | 2026-10-14 |
| 6 | VTWO Vanguard Russell 2000 ETF | Vanguard | 0.01% | $2.5M | — | 2026-09-30 |
| 7 | IWC iShares Micro-Cap ETF | iShares (BlackRock) | 0.09% | $1.2M | $1.3B | 2026-10-14 |
| 8 | VHT Vanguard Health Care ETF | Vanguard | 0.00% | $913,057 | — | 2026-09-30 |
| 9 | VTWG Vanguard Russell 2000 Growth ETF | Vanguard | 0.03% | $462,182 | — | 2026-09-30 |
| 10 | VFMO Vanguard U.S. Momentum Factor ETF | Vanguard | 0.01% | $267,702 | — | 2026-10-14 |
| 11 | LABU Direxion Daily S&P Biotech Bull 3X ETF | Direxion | 0.03% | $185,769 | — | 2026-10-15 |
| 12 | RSSL Global X Russell 2000 ETF | Global X | 0.01% | $173,048 | — | 2026-10-15 |
| 13 | IWV iShares Russell 3000 ETF | iShares (BlackRock) | 0.00% | $146,683 | $20.5B | 2026-10-14 |
| 14 | VTHR Vanguard Russell 3000 ETF | Vanguard | 0.00% | $41,757 | — | 2026-09-30 |
| 15 | DFSU Dimensional US Sustainability Core 1 ETF | Dimensional | 0.00% | $33,626 | $2.4B | 2026-10-14 |
| 16 | ITWO ProShares Russell 2000 High Income ETF | ProShares | 0.01% | $21,141 | — | 2026-10-15 |
| 17 | URTY ProShares UltraPro Russell2000 | ProShares | 0.01% | $16,711 | — | 2026-10-15 |
| 18 | UWM ProShares Ultra Russell2000 | ProShares | 0.00% | $9,947 | — | 2026-10-15 |
| 19 | HDG ProShares Hedge Replication ETF | ProShares | 0.00% | $437 | — | 2026-10-15 |
| 20 | RB ProShares Russell 2000 Dynamic Buffer ETF | ProShares | 0.01% | $150 | — | 2026-10-15 |
Fundamentals
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
Metrics
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.
Trailing P/E
—
TTM Diluted EPS
$-7.63
TTM Revenue
$11.88M
TTM Net Income
$-145.95M
TTM Op. Cash Flow
$-72.68M
Quarterly figures (12 quarters)
| Quarter | Period End | Revenue | Net Income | Diluted EPS | Op. Cash Flow |
|---|---|---|---|---|---|
| Q2 '26 | 2026-06-30 | — | $-22.69M | $-0.74 | $-19.46M |
| Q1 '26 | 2026-03-31 | $1.04M | $-21.26M | $-0.70 | $-8.94M |
| Q4 '25 | 2025-12-31 | $10.84M | $-81.06M | $-4.92 | $-26.74M |
| Q3 '25 | 2025-09-30 | — | $-20.95M | $-1.27 | $-17.54M |
| Q2 '25 | 2025-06-30 | — | $-19.00M | $-4.93 | $-16.40M |
| Q3 '23 | 2023-09-30 | $32.04M | $3.98M | $0.05 | $7.58M |
| Q2 '23 | 2023-06-30 | $29.33M | $1.85M | $0.02 | $4.53M |
| Q1 '23 | 2023-03-31 | $24.93M | $2.24M | $0.03 | $10.42M |
| Q4 '22 | 2022-12-31 | $101.50M | $-29.91M | $-15.27 | $42.30M |
| Q3 '22 | 2022-09-30 | — | $-4.88M | $-2.40 | $-7.28M |
| Q2 '22 | 2022-06-30 | — | $51.63M | $24.60 | $-12.29M |
| Q1 '22 | 2022-03-31 | $794.00K | $-14.54M | $-6.90 | $-12.05M |
Q2 2026 • period ending 2026-06-30 • filed 2026-07-30
Valuation
Ratios derived from TTM financials and the current market price, sampled daily. History chart shows how expensive the stock is today relative to its own recent past.
Price Multiples
- P/E — price / TTM earnings. Rough market rule: 10–15 value, 15–25 market, >30 growth/premium. Negative when earnings are negative.
- P/B — price / book value. Useful for financials and asset-heavy names; meaningless for asset-light software.
- P/S — price / TTM revenue. Useful when earnings are negative or noisy (early-stage growth).
- EV/EBITDA — capital-structure-neutral. <10 cheap, 10–15 reasonable, >20 rich. Good for comparing across leverage profiles.
- EV/Sales — like P/S but accounts for debt + cash. Compare within sector.
Profitability & Yields
- ROE — return on equity. >15% strong, >25% exceptional. Caution: high leverage inflates ROE.
- ROA — return on assets. Leverage-neutral; >5% solid, >10% exceptional.
- Div Yield — annual dividend / price. Compare to 10Y Treasury; sustained yield >6% often signals distress.
- FCF Yield — free cash flow / market cap. >5% is attractive; negative means burning cash.
Balance Sheet
- Debt/Equity — leverage. <1 conservative, >2 aggressive. Sector-dependent (utilities naturally high, tech low).
- Current Ratio — short-term liquidity. >1.5 comfortable, <1 raises short-term solvency flags.
Reading the history chart
- Compare current level to the 3-year band: near the high end = relatively expensive; near the low = relatively cheap.
- Multiples expanding while earnings are flat = sentiment-driven rally.
- Multiples compressing while earnings grow = value coming from fundamentals.
P/E
—
P/B
1.59
P/S
21.89
EV/EBITDA
—
EV/Sales
7.45
ROE
-89.4%
ROA
-79.9%
Div Yield
0.00%
FCF Yield
-27.94%
Debt/Equity
0.00
Current Ratio
—
Market Cap
$260.15M
as of 2026-10-16
Short Interest & Float
Regulatory short-interest reports publish on a bi-weekly settlement cadence; short-volume is reported daily by the trade-reporting facilities. Float is derived from insider-ownership filings.
Metric definitions
- Short Interest — total shares currently sold short as of the settlement date. Lags real time by ~8 business days.
- SI % of Float — short interest / free float. The key crowding metric.
- Days to Cover — short interest / avg daily volume. How many full trading days it would take shorts to buy back. High DTC + catalyst = squeeze fuel.
- Short Vol Ratio — today's short-sale volume / total volume. Intraday selling pressure proxy (not the same as short interest).
- Free Float — shares available for public trading (total shares minus insider / restricted).
- Float % — free float / shares outstanding. <50% = tightly held, more prone to squeezes.
How to read the signals
- SI % of Float < 5% — typical, no particular signal.
- 5–15% — elevated; watch for catalysts (earnings, guidance, macro).
- 15–30% — heavily shorted; tight-float names in this range have produced notable squeezes historically.
- >30% — extreme; borrow is likely expensive and squeeze risk is material.
- Days to Cover > 5 combined with high SI% amplifies squeeze potential.
History chart
- Trend matters more than level. Rapidly rising short interest often precedes negative catalysts or heavy hedging.
- A sudden drop in SI after a rally may indicate a squeeze in progress.
Short interest is reported mid-month and end-of-month; short volume is daily.
Short Interest
4.78M
SI % of Float
22.90%
Days to Cover
6.85
Short Vol Ratio
69.3%
Free Float
20.86M
Float %
75.7%
Short interest 2026-09-30 • Short volume 2026-10-16 • Float 2026-08-14